Zobrazeno 1 - 10
of 21
pro vyhledávání: '"K E Paulson"'
Publikováno v:
Oncogene. 29:5083-5094
Oncogene-mediated premature senescence has emerged as a potential tumor-suppressive mechanism in early cancer transitions. Many studies showed that Ras and p38 mitogen-activated protein kinase (MAPK) participate in premature senescence. Our previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87532ffe98eff5a9e8949c2728114639
https://doi.org/10.1038/onc.2010.252
https://doi.org/10.1038/onc.2010.252
Publikováno v:
The Journal of Immunology. 159:2445-2451
Macrophages (Mphi) from old mice produce more PGE2 than those from young mice, contributing to the dysregulation of the immune and inflammatory responses with age. This study was conducted to determine the mechanisms of the age-associated increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::085b645909f8d5b8b793d009345081f6
https://doi.org/10.4049/jimmunol.159.5.2445
https://doi.org/10.4049/jimmunol.159.5.2445
Autor:
R. S. Peterson, Derek E. Clevidence, A. Porcella, D. G. Overdier, Honggang Ye, K. E. Paulson, Robert H. Costa
Publikováno v:
Developmental Biology. 166:195-209
The hepatocyte nuclear factor-3 (HNF-3)/forkhead (fkh) proteins consist of an extensive family of tissue-specific and developmental gene regulators which share homology within the winged helix DNA binding motif. We report on the isolation of a new fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86ed3760f8a42c46c2d5b5f98aac7c1
https://doi.org/10.1006/dbio.1994.1307
https://doi.org/10.1006/dbio.1994.1307
Publikováno v:
Molecular and Cellular Biology. 10:1841-1852
In situ hybridization and other data showed that all hepatocytes express glutathione-S-transferase (GST) Ya mRNA but that specifically pericentral cells can be induced 15- to 20-fold with 3-methylcholanthrene (3-MC). In order to identify DNA sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14ee259f3ce32f1dc4247467cba039b3
https://doi.org/10.1128/mcb.10.5.1841
https://doi.org/10.1128/mcb.10.5.1841
Regulation of PDGF production and ERK activation by estrogen is associated with TSC2 gene expression
Publikováno v:
American journal of physiology. Cell physiology. 285(2)
Mechanisms that regulate the growth response to estrogen (17β-estradiol, E2) are poorly understood. Recently, loss of function of the tuberous sclerosis complex 2 ( TSC2) gene has been associated with E2-related conditions that are characterized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f799863b61c41179917b531cc94183e
https://pubmed.ncbi.nlm.nih.gov/12700139
https://pubmed.ncbi.nlm.nih.gov/12700139
Publikováno v:
The Journal of biological chemistry. 274(16)
The proliferative potential of the liver has been well documented to decline with age. However, the molecular mechanism of this phenomenon is not well understood. Cellular proliferation is the result of growth factor-receptor binding and activation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de5c624107cc78b3b6cf8b964d497099
https://pubmed.ncbi.nlm.nih.gov/10196236
https://pubmed.ncbi.nlm.nih.gov/10196236
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(5)
Macrophages (Mphi) from old mice produce more PGE2 than those from young mice, contributing to the dysregulation of the immune and inflammatory responses with age. This study was conducted to determine the mechanisms of the age-associated increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02fa886302dc758b081d8c871190d052
https://pubmed.ncbi.nlm.nih.gov/9278337
https://pubmed.ncbi.nlm.nih.gov/9278337
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(1)
Because of its critical role in the control of cell proliferation and differentiation, we postulated that E2F-1 could have a role in murine development. To this end, the organ and developmental expression of the E2F-1 transcription factor was analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88e10e92dba1acf5314ae9c846df9f9b
https://pubmed.ncbi.nlm.nih.gov/8788032
https://pubmed.ncbi.nlm.nih.gov/8788032
The rat glutathione S-transferase Ya gene xenobiotic response element (XRE) has both constitutive and xenobiotic-inducible activity. We present evidence that the XRE is regulated by both the constitutive C/EBP transcription factor and the xenobiotic-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb99c823b8560fdc3927c872a8c2e64
https://europepmc.org/articles/PMC359997/
https://europepmc.org/articles/PMC359997/
Publikováno v:
Gene expression. 3(3)
We have examined the dynamics of positional gene expression in mouse liver using the carbohydrate induction of lipogenic genes as a model. Using a protocol of fasting and refeeding a high-carbohydrate, no-fat diet to obtain maximal induction, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d0b416480a21a25f49ed97702e813a8
https://pubmed.ncbi.nlm.nih.gov/8019127
https://pubmed.ncbi.nlm.nih.gov/8019127