Zobrazeno 1 - 10
of 111
pro vyhledávání: '"K E L McColl"'
Autor:
Emad M. El-Omar, K. E. L. Mccoll
Publikováno v:
Alimentary Pharmacology & Therapeutics. 9:341-347
Gastrin releasing peptide (GRP) has proved to be a particularly valuable tool in detecting disturbances of gastric secretory function associated with duodenal ulcer disease and Helicobacter pylori infection, and it has furthered understanding of the
Publikováno v:
Alimentary Pharmacology & Therapeutics. 2:263-268
The effect of 7 days of oral dosing with 5 mg day-1 and 20 mg day-1 omeprazole on basal and pentagastrin-stimulated gastric acid output was studied in nine duodenal ulcer patients. Basal acid output measured 5-6 h post-dosing was decreased by a mean
Publikováno v:
Alimentary Pharmacology & Therapeutics. 5:391-398
Our previous study demonstrated rebound nocturnal acid hypersecretion after a 4-week course of nizatidine. Nocturnal acid output was increased by 77% two days after discontinuing treatment compared with pretreatment values. To confirm this effect wit
Publikováno v:
Gut. 54:1527-1535
Background and aims: When saliva, with its high nitrite content derived from the enterosalivary recirculation of dietary nitrate, meets acidic gastric juice, the nitrite is converted to nitrous acid, nitrosative species, and nitric oxide. In healthy
Publikováno v:
Alimentary Pharmacology and Therapeutics. 22:539-545
Summary Background : The gastric juice concentration of vitamin C is reduced in subjects with elevated intragastric pH. This is probably because of the fact that the vitamin is unstable at non-acidic pH and undergoes irreversible denaturation. Aim :
Review article: Helicobacter pylori and gastro-oesophageal reflux disease − the European perspective
Autor:
K. E. L. Mccoll
Publikováno v:
Alimentary Pharmacology & Therapeutics. 20:36-39
There is substantive epidemiological evidence of a negative association between Helicobacter pylori infection and reflux disease and its malignant complications. A plausible mechanism by which the infection might protect against reflux disease is by
Publikováno v:
Gut. 53:168-173
Background and aims: Oesophageal pH is conventionally recorded from a point 5 cm above the lower oesophageal sphincter. However, the mucosal changes of reflux oesophagitis and intestinal metaplasia tend to affect the segment of oesophagus distal to t
Autor:
Y Y, Lee, K E L, McColl
Publikováno v:
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. 28(4)
Obesity is a major reason for the recent increase in incidence of reflux disease and cancers at the distal esophagus and gastroesophageal junction (GOJ) and is mediated through a rise in the intra-abdominal pressure (IAP) but the exact mechanisms are
Autor:
K. E. L. Mccoll
Publikováno v:
Alimentary Pharmacology & Therapeutics. 15:10-13
Dyspepsia, and the issue of Helicobacter pylori status, can present significant controversies in clinical management. Both primary physicians and gastroenterologists should be aware of options for the treatment of patients with dyspepsia. This articl
Publikováno v:
Alimentary Pharmacology & Therapeutics. 13:1505-1509
Aims : To determine the prevalence of dyspepsia and associated antisecretory medication usage, and their associations with H. pylori infection in the general population. In addition, to compare the importance of H. pylori infection relative to other