Zobrazeno 1 - 10 of 137 pro vyhledávání: '"K E, Willard"'
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Akademický článek
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HTLV-I infection of WE17/10 CD4+ cell line leads to progressive alteration of Ca2+ influx that eventually results in loss of CD7 expression and activation of an antiapoptotic pathway involving AKT and BAD which paves the way for malignant transformation
Autor: H, Akl, B M, Badran, N El, Zein, N E, Zein, F, Bex, C, Sotiriou, K E, Willard-Gallo, A, Burny, P, Martiat
Publikováno v: Leukemia. 21:788-796
Adult T-cell leukemia/lymphoma (ATLL) is a malignancy slowly emerging from human T-cell leukemia virus type 1 (HTLV-I)-infected mature CD4(+) T-cells. To characterize the molecular modifications induced by HTLV-I infection, we compared HTLV-I-infecte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9291560a0748c44d7ad0e216b8e06ac1
https://doi.org/10.1038/sj.leu.2404585
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3
Identification and Synthesis of an Oxidation Product of Tilmicosin
Autor: Robin S. Readnour, James Patrick Leeds, K. E. Willard, Douglas E. Kiehl, Christine M. Cleveland, Herbert A. Kirst, Paul R. Klink
Publikováno v: Journal of Agricultural and Food Chemistry. 46:3265-3271
During formulation development of the veterinary macrolide antibiotic tilmicosin, an oxidation product of the parent molecule was identified. Use of liquid chromatography/mass spectrometry and nuclear magnetic resonance spectroscopy characterized the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73b420be13a026ca2f389aa29b6a1407
https://doi.org/10.1021/jf9710746
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4
Comparison of the VIDAS Clostridium difficile toxin A immunoassay with C. difficile culture and cytotoxin and latex tests
Autor: K E Willard, J J Holter, Lance R. Peterson, Carol J. Shanholtzer, Dale N. Gerding, M M Olson
Publikováno v: Journal of Clinical Microbiology. 30:1837-1840
The VIDAS Clostridium difficile toxin A immunoassay (CDA) is a new, automated, enzyme-linked fluorescent-antibody assay for detection of C. difficile toxin A antigen in stool specimens. Simultaneous, parallel testing was performed by using the VIDAS
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5c367ab9304bf9cda13be193c87563
https://doi.org/10.1128/jcm.30.7.1837-1840.1992
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6
Synthesis and structure-activity relationships of new 9-N-alkyl derivatives of 9(S)-erythromycylamine
Autor: H A, Kirst, J A, Wind, J P, Leeds, K E, Willard, M, Debono, R, Bonjouklian, J M, Greene, K A, Sullivan, J W, Paschal, J B, Deeter
Publikováno v: Journal of Medicinal Chemistry. 33:3086-3094
A series of new 9-N-alkyl derivatives of 9(S)-erythromycylamine has been synthesized by reductive alkylation of erythromycylamine with aliphatic aldehydes and sodium cyanoborohydride. Alternative syntheses employing hydrogenation methods have also be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633b1eb921c977519886960bc5c8af08
https://doi.org/10.1021/jm00173a028
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7
Akademický článek
Chemoinformatic regression methods and their applicability domain.
Autor: Dutschmann TM; Institute of Medicinal and Pharmaceutical Chemistry, University of Technology Braunschweig, 38106, Braunschweig, Germany., Schlenker V; Institute of Medicinal and Pharmaceutical Chemistry, University of Technology Braunschweig, 38106, Braunschweig, Germany., Baumann K; Institute of Medicinal and Pharmaceutical Chemistry, University of Technology Braunschweig, 38106, Braunschweig, Germany.
Publikováno v: Molecular informatics [Mol Inform] 2024 Jul; Vol. 43 (7), pp. e202400018. Date of Electronic Publication: 2024 May 28.
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Down-modulation of TCR/CD3 surface complexes after HIV-1 infection is associated with differential expression of the viral regulatory genes
Autor: K E, Willard-Gallo, M, Furtado, A, Burny, S M, Wolinsky
Publikováno v: European journal of immunology. 31(4)
We have investigated the mechanism(s) involved in progressive abrogation of CD3-gamma gene expression after HIV-1 or HIV-2 infection. A comparison of intracellular virus expression with T cell receptor surface density, revealed both high and low leve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8066f64c883a38e316347a254f100ce
https://pubmed.ncbi.nlm.nih.gov/11298321
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9
Closing the clinical laboratory testing loop with information technology
Autor: D P, Connelly, K E, Willard, J H, Hallgren, B H, Sielaff
Publikováno v: American journal of clinical pathology. 105(4 Suppl 1)
Information technology can enhance the effectiveness of the part of the laboratory testing loop that occurs outside of the clinical laboratory. That external component involves the presentation of laboratory results and related information to physici
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fd4a1ec4eef6d60fe0d721c0fc0b9c0e
https://pubmed.ncbi.nlm.nih.gov/8607461
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10
User interface reengineering. Innovative applications of bar coding in a clinical microbiology laboratory
Autor: K E, Willard, C J, Shanholtzer
Publikováno v: Archives of pathologylaboratory medicine. 119(8)
Some clinical laboratory departments (such as microbiology) provide extensive reporting of text and other data not generated by instruments that can be interfaced to a laboratory information system. These data are usually entered into the laboratory
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96972c29a57638afd8f432e29b4d3eab
https://pubmed.ncbi.nlm.nih.gov/7646327
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