Bumetanide Prevents Brain Trauma-Induced Depressive-Like Behavior

Autor: Emmanuelle Goubert, Marc Altvater, Marie-Noelle Rovira, Ilgam Khalilov, Morgane Mazzarino, Anne Sebastiani, Michael K. E. Schaefer, Claudio Rivera, Christophe Pellegrino

Publikováno v: Frontiers in Molecular Neuroscience, Vol 12 (2019)

Brain trauma triggers a cascade of deleterious events leading to enhanced incidence of drug resistant epilepsies, depression, and cognitive dysfunctions. The underlying mechanisms leading to these alterations are poorly understood and treatment that

Externí odkaz: https://doaj.org/article/0ee257e4b57d4e2cb4b70871dff66cd6

Bumetanide prevents brain trauma-induced depressive-like behavior

Autor: Emmanuelle Goubert, Marc Altvater, Marie-Noelle Rovira, Ilgam Khalilov, Morgane Mazzarino, Anne Sebastiani, Michael K. E. Schaefer, Claudio Rivera, Christophe Pellegrino

Publikováno v: Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Frontiers Media, 2019, 12, pp.12. ⟨10.3389/fnmol.2019.00012⟩
Frontiers in Molecular Neuroscience, Vol 12 (2019)

Brain trauma triggers a cascade of deleterious events leading to enhanced incidence of drug resistant epilepsies, depression and cognitive dysfunctions. The underlying mechanisms leading to these alterations are poorly understood and treatment that a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2275f470678119a8c2b345dfa0c241

Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival

Autor: Anastasia Ludwig, Ilona Chudotvorova, Michael K. E. Schaefer, Igor Medina, Severine Corby, Christophe Pellegrino, Piotr Bregestovski, Marat Mukhtarov, Yuriy Salyha, Hélène Becq, Olena Gubkina, Sergey Salozhin

Publikováno v: The Journal of Physiology. 589:2475-2496

KCC2 is a neuron-specific potassium-chloride co-transporter controlling intracellular chloride homeostasis in mature and developing neurons. It is implicated in the regulation of neuronal migration, dendrites outgrowth and formation of the excitatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8d15798cb5d3d134113548426de13c6
https://doi.org/10.1113/jphysiol.2010.203703

Progressive motor neuronopathy: a critical role of the tubulin chaperone TBCE in axonal tubulin routing from the Golgi apparatus

Autor: Jean-Louis Guénet, Georg Haase, Natalia Martin, Michael K. E. Schaefer, Henning Schmalbruch, C. Lopez, Emmanuelle Buhler

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, 2007, 27 (33), pp.8779-89. ⟨10.1523/JNEUROSCI.1599-07.2007⟩
Journal of Neuroscience, Society for Neuroscience, 2007, 27 (33), pp.8779-89. ⟨10.1523/JNEUROSCI.1599-07.2007⟩

Axonal degeneration represents one of the earliest pathological features in motor neuron diseases. We here studied the underlying molecular mechanisms in progressive motor neuronopathy (pmn) mice mutated in the tubulin-specific chaperone TBCE. We dem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c597103e87c59039529d8a57b94d13e6
https://www.hal.inserm.fr/inserm-00195963

Chromatin alterations surrounding the BCR/ABL fusion gene in K562 cells

Autor: K E, Schaefer-Rego, D, Leibowitz, J G, Mears

Publikováno v: Oncogene. 5(11)

Chronic myelogenous leukemia (CML) is characterized by the presence of a novel fusion gene comprised of portions of the BCR gene from chromosome (ch) 22 and the ABL gene from ch 9. The present study was designed to identify regulatory DNA regions as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8cd09477403b42ba53956fde2149f9ac
https://pubmed.ncbi.nlm.nih.gov/2267134