Zobrazeno 1 - 10
of 21
pro vyhledávání: '"K E, Mostov"'
Publikováno v:
Traffic (Copenhagen, Denmark). 1(6)
Quantitative confocal microscopic analyses of living, polarized MDCK cells demonstrate different pH profiles for apical and basolateral endocytic pathways, despite a rapid and extensive intersection between the two. Three-dimensional characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d26381ede2ade32ce184850e5395ada
https://pubmed.ncbi.nlm.nih.gov/11208134
https://pubmed.ncbi.nlm.nih.gov/11208134
Publikováno v:
The Journal of biological chemistry. 275(40)
Protease-activated receptor-1 (PAR1), a G protein-coupled receptor (GPCR) for thrombin, is irreversibly activated by a proteolytic mechanism, then internalized and degraded in lysosomes. The latter is critical for temporal fidelity of thrombin signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f93d551b50c82008d283572ecf9150bc
https://pubmed.ncbi.nlm.nih.gov/10893235
https://pubmed.ncbi.nlm.nih.gov/10893235
Publikováno v:
The Journal of biological chemistry. 275(27)
Caveolin-1 is a principal component of caveolae membranes that may function as a transformation suppressor. For example, the human caveolin-1 gene is localized to a suspected tumor suppressor locus (D7S522; 7q31.1) that is deleted in human cancers, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cd71404a8447003dde69b97e220e711
https://pubmed.ncbi.nlm.nih.gov/10748172
https://pubmed.ncbi.nlm.nih.gov/10748172
Publikováno v:
The Journal of biological chemistry. 273(26)
Brefeldin A (BFA) treatment of Caco-2 cells (5 microg/ml for 12 h) reduced by 90% the cholesterol, but not the phospholipid (PL), levels of the basolateral membrane (BLM), thus altering its PL/cholesterol molar ratio from 2.6 to 22.0, and decreasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58bae6fe1f424a34592549c2f9c07bba
https://pubmed.ncbi.nlm.nih.gov/9632671
https://pubmed.ncbi.nlm.nih.gov/9632671
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(2)
Polymeric IgA (pIgA) is transcytosed across epithelial cells and into external secretions by the polymeric Ig receptor (pIgR). Binding of dimeric IgA (dIgA) to the pIgR stimulates transcytosis of the pIgR. The pIgA in secretions is found as dimers (d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11a19ebc428f5432d25464285e7904c9
https://pubmed.ncbi.nlm.nih.gov/7608549
https://pubmed.ncbi.nlm.nih.gov/7608549
Autor:
K E, Mostov
Publikováno v:
Histology and histopathology. 10(2)
The plasma membrane of polarized epithelial cells is divided into apical and basolateral surfaces with different compositions. Proteins can be sent directly from the trans Golgi network (TGN) to either surface, or can be sent first to one surface and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1cd8458e153debcff98a52e4e502bd04
https://pubmed.ncbi.nlm.nih.gov/7599439
https://pubmed.ncbi.nlm.nih.gov/7599439
Publikováno v:
The Journal of biological chemistry. 269(22)
S726 of the cytoplasmic domain of the polymeric immunoglobulin receptor (pIgR) resides within a consensus sequence for phosphorylation by protein kinases A, G, and C, and casein kinase II. Mutation of S726 to Ala and expression of this mutant pIgR in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96caaae656d19197a627e6dfe7b838ba
https://pubmed.ncbi.nlm.nih.gov/8195218
https://pubmed.ncbi.nlm.nih.gov/8195218
Autor:
M, Bomsel, K E, Mostov
Publikováno v:
The Journal of biological chemistry. 268(34)
In endosomes the polymeric immunoglobulin receptor (pIgR) is sorted into transcytotic vesicles. Transcytosis of the pIgR in polarized Madin-Darby canine kidney (MDCK) cells is regulated both by phosphorylation of Ser664 and by binding of ligand, dime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de0774b5881bc1a651981180b8fc44ec
https://pubmed.ncbi.nlm.nih.gov/8245019
https://pubmed.ncbi.nlm.nih.gov/8245019
Autor:
G, Apodaca, K E, Mostov
Publikováno v:
The Journal of biological chemistry. 268(31)
Two signals are known that regulate the entry of the polymeric immunoglobulin receptor (pIgR) into the transcytotic pathway: binding of the ligand, dimeric IgA, and phosphorylation of Ser664 in the cytoplasmic domain of the receptor. Mutation of Ser6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7983144440f60dcbf622afcc8c7c209
https://pubmed.ncbi.nlm.nih.gov/8226896
https://pubmed.ncbi.nlm.nih.gov/8226896
Publikováno v:
The Journal of biological chemistry. 268(16)
In the classical secretory pathway proteins containing a signal peptide are translocated from the cytoplasm of the cell into the lumen of the endoplasmic reticulum (ER). From the ER they are transported to the Golgi apparatus and finally to the plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59be9fbeb1cbd0faf4bfa6cb5889381c
https://pubmed.ncbi.nlm.nih.gov/8505302
https://pubmed.ncbi.nlm.nih.gov/8505302