Zobrazeno 1 - 10
of 16
pro vyhledávání: '"K E, Chapman"'
Autor:
I, Sánchez Fernández, M, Gaínza-Lein, N S, Abend, A E, Anderson, R, Arya, J N, Brenton, J L, Carpenter, K E, Chapman, J, Clark, W D, Gaillard, T A, Glauser, J L, Goldstein, H P, Goodkin, A R, Helseth, M C, Jackson, K, Kapur, Y-C, Lai, T L, McDonough, M A, Mikati, A, Nayak, K, Peariso, J J, Riviello, R C, Tasker, D, Tchapyjnikov, A A, Topjian, M S, Wainwright, A, Wilfong, K, Williams, T, Loddenkemper, William, Gaillard
Publikováno v:
Neurology. 90:e1692-e1701
ObjectiveTo identify factors associated with treatment delays in pediatric patients with convulsive refractory status epilepticus (rSE).MethodsThis prospective, observational study was performed from June 2011 to March 2017 on pediatric patients (1 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b67ab0949d68962e5d18d60b14bd631
https://doi.org/10.1212/wnl.0000000000005488
https://doi.org/10.1212/wnl.0000000000005488
Decreasing case fatality rate following invasive pneumococcal disease, North East England, 2006–2016
Publikováno v:
Epidemiology and Infection
Declining mortality following invasive pneumococcal disease (IPD) has been observed concurrent with a reduced incidence due to effective pneumococcal conjugate vaccines. However, with IPD now increasing due to serotype replacement, we undertook a sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b602899bfd7667ef5eac4b623c7551
https://doi.org/10.1017/s0950268819000657
https://doi.org/10.1017/s0950268819000657
Publikováno v:
Epidemiology and Infection
SUMMARYInvasive pneumococcal disease (IPD), caused by infection with Streptococcus pneumoniae, has a substantial global burden. There are over 90 known serotypes of S. pneumoniae with a considerable body of evidence supporting serotype-specific morta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065578129d0144d346ee80c07af81aae
https://doi.org/10.1017/s0950268816000856
https://doi.org/10.1017/s0950268816000856
Publikováno v:
Journal of Public Health. 35:558-569
Background Some communicable diseases disproportionately affect poor and vulnerable groups. Invasive pneumococcal disease (IPD) is an important cause of morbidity and mortality; however, the relationship between IPD and deprivation has not been well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4376505ff257c18800070de507b563
https://doi.org/10.1093/pubmed/fdt011
https://doi.org/10.1093/pubmed/fdt011
Publikováno v:
Epidemiol Infect
SUMMARYThe 7-valent pneumococcal conjugate vaccine (PCV7) has been included in the routine childhood immunization programme in the UK since September 2006. A population-based study of serotypes causing invasive pneumococcal disease (IPD) post-PCV7 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f14e938e99135e969f46fa6f886349
https://doi.org/10.1017/s0950268812000763
https://doi.org/10.1017/s0950268812000763
Autor:
E A, Rog-Zielinska, M-A, Craig, J R, Manning, R V, Richardson, G J, Gowans, D R, Dunbar, K, Gharbi, C J, Kenyon, M C, Holmes, D G, Hardie, G L, Smith, K E, Chapman
Publikováno v:
Cell Death and Differentiation
Glucocorticoid levels rise dramatically in late gestation to mature foetal organs in readiness for postnatal life. Immature heart function may compromise survival. Cardiomyocyte glucocorticoid receptor (GR) is required for the structural and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b71ec597ed1c2a8a488df6ad35a72e3
https://pubmed.ncbi.nlm.nih.gov/25361084
https://pubmed.ncbi.nlm.nih.gov/25361084
Autor:
L J, Williams, V, Lyons, I, MacLeod, V, Rajan, G J, Darlington, V, Poli, J R, Seckl, K E, Chapman
Glucocorticoid action within individual cells is potently modulated by 11beta-hydroxysteroid dehydrogenase (11beta-HSD), which, by interconverting active and inert glucocorticoids, determines steroid access to receptors. Type 1 11beta-HSD (11beta-HSD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c1bcdf68c038fb88b4d23b42a2917284
http://hdl.handle.net/2318/33902
http://hdl.handle.net/2318/33902
Publikováno v:
Bioelectromagnetics. 20(2)
Drosophila larvae reared inside a micro-metal box with an internal field strength 0.004 microT, were treated with a magnetic field of 50 Hz, 8 microT. for 20 min. Control experienced 0.004 microT. Cellular transcript levels were assessed using slot b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aaf45b86689f5a399dfef19dd833d9e3
https://pubmed.ncbi.nlm.nih.gov/10029140
https://pubmed.ncbi.nlm.nih.gov/10029140
Autor:
J R, Seckl, K E, Chapman
Publikováno v:
European journal of biochemistry. 249(2)
11Beta-hydroxysteroid dehydrogenases (11beta-HSD) catalyse the interconversion of active glucocorticoids (cortisol, corticosterone) and their inert 11-keto derivatives (cortisone, 11-dehydrocorticosterone). The type-2 isozyme (11beta-HSD-2) is a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9feb1ea078146d6590bd0779c469a252
https://pubmed.ncbi.nlm.nih.gov/9370341
https://pubmed.ncbi.nlm.nih.gov/9370341
Publikováno v:
Annals of the Rheumatic Diseases. 72:A421.1-A421
Background It is established that Vitamin D deficiency is common in patients with Rheumatoid Arthritis (RA)[1], and that the prevalence of chronic infection is increased in RA [2]. Vitamin D deficiency has been proposed as a factor in the increased p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b8aa806c5e612fa8a98828ececa455
https://doi.org/10.1136/annrheumdis-2013-eular.1277
https://doi.org/10.1136/annrheumdis-2013-eular.1277