Zobrazeno 1 - 10 of 29 pro vyhledávání: '"K Deaton"'
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Akademický článek
Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease
Autor: Florine E.M. Scholte, Marko Zivcec, John V. Dzimianski, Michelle K. Deaton, Jessica R. Spengler, Stephen R. Welch, Stuart T. Nichol, Scott D. Pegan, Christina F. Spiropoulou, Éric Bergeron
Publikováno v: Cell Reports, Vol 20, Iss 10, Pp 2396-2407 (2017)
Antiviral responses are regulated by conjugation of ubiquitin (Ub) and interferon-stimulated gene 15 (ISG15) to proteins. Certain classes of viruses encode Ub- or ISG15-specific proteases belonging to the ovarian tumor (OTU) superfamily. Their activi
Externí odkaz: https://doaj.org/article/2913f622b2624efda670531f1ee47f80
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3
Divining God's Favour and Diverting his Wrath
Autor: Andrew K. Deaton
Publikováno v: Miracles, Political Authority and Violence in Medieval and Early Modern History ISBN: 9781003168294
Miracles, Political Authority and Violence in Medieval and Early Modern History
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4255565471fac45f8c0390bc1ac583cf
https://doi.org/10.4324/9781003168294-6
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4
G336(P) Inpatient management of medically unstable restrictive eating disorders
Autor: E Allison, K Deaton
Publikováno v: British association for paediatric nephrology.
Aims Serious short and long term complications as well as a significant mortality risk result from the prolonged semi starvation associated with restrictive eating disorders unless prompt and early medical treatment and refeeding are provided. To aud
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91d447dfd1fa17c27db3d9b43f840791
https://doi.org/10.1136/archdischild-2020-rcpch.289
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5
The vOTU domain of highly-pathogenic porcine reproductive and respiratory syndrome virus displays a differential substrate preference
Autor: Allyn Spear, Michelle K. Deaton, Scott D. Pegan, Kay S. Faaberg
Publikováno v: Virology. :247-253
Arterivirus genus member Porcine reproductive and respiratory syndrome virus (PRRSV) causes an economically devastating disease, recently exacerbated by the emergence of highly pathogenic strains (HP-PRRSV). Within the nonstructural protein 2 of PRRS
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3945d924848cbc177b2dcbb8216f63
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6
Diversity of Ubiquitin and ISG15 Specificity among Nairoviruses' Viral Ovarian Tumor Domain Proteases
Autor: Michelle K. Deaton, Glenn C. Capodagli, Erica A. Baker, Scott D. Pegan, Ryan J. Lumpkin
Publikováno v: Journal of Virology
Nairoviruses are responsible for numerous diseases that affect both humans and animal. Recent work has implicated the viral ovarian tumor domain (vOTU) as a possible nairovirus virulence factor due to its ability to edit ubiquitin (Ub) bound to cellu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da6a7e860a15ee1f83b3151fb099891
https://doi.org/10.1128/jvi.03252-12
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7
Biochemical and Structural Insights into the Preference of Nairoviral DeISGylases for Interferon-Stimulated Gene Product 15 Originating from Certain Species
Autor: Eric Bergeron, N. J. Mank, Scott D. Pegan, Courtney M. Daczkowski, Michelle K. Deaton, M. M. Parham, G. K. Whitney, John V. Dzimianski
Publikováno v: Journal of Virology
The regulation of the interferon type I (IFN-I) response has been shown to rely on posttranslational modification by ubiquitin (Ub) and Ub-like interferon-stimulated gene product 15 (ISG15) to stabilize, or activate, a variety of IFN-I signaling and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f42ba64815ae63c362dbe6215266f2c
https://europepmc.org/articles/PMC5008091/
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8
Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency-Associated Mutation
Autor: Kingshuk Ghosh, Stephen P. Ray, Glenn C. Capodagli, Scott D. Pegan, Lucas Sawle, Lauren A. F. Calkins, David Patterson, Michelle K. Deaton
Publikováno v: Biochemistry. 51:6701-6713
Adenylosuccinate lyase (ADSL) deficiency is a rare autosomal recessive disorder, which causes a defect in purine metabolism resulting in neurological and physiological symptoms. ADSL executes two nonsequential steps in the de novo synthesis of AMP: t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977db4cf748188bccda82c1b29e2d571
https://doi.org/10.1021/bi300796y
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9
A Broadband Ocean-Bottom Seismometer System Based on a 1-Hz Natural Period Geophone
Autor: T. K. Deaton, Jacques C. Lemire, Spahr C. Webb
Publikováno v: Bulletin of the Seismological Society of America. 91:304-312
Recent work with broadband sensors has demonstrated that useful data can be obtained from seismic sensors deployed on the deep seafloor for periods as long as 300 sec, but ocean-bottom seismometer (OBS) systems using conventional broadband sensors ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e21162bcd232b60f50506d25aed7e1cc
https://doi.org/10.1785/0120000110
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10
Heterogeneous nuclear ribonucleoprotein K, an RNA-binding protein, is required for optic axon regeneration in Xenopus laevis
Autor: Sarah K. Deaton, Hurong Yu, Yuanyuan Liu, Ben G. Szaro
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(10)
Axotomized optic axons ofXenopus laevis, in contrast to those of mammals, retain their ability to regenerate throughout life. To better understand the molecular basis for this successful regeneration, we focused on the role of an RNA-binding protein,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16440942e6e742baf1c04904cd4e4ab8
https://pubmed.ncbi.nlm.nih.gov/22399778
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