Zobrazeno 1 - 10
of 31
pro vyhledávání: '"K David Li"'
Autor:
Sabarinath V. Radhakrishnan, Tim Luetkens, Sandra D. Scherer, Patricia Davis, Erica R. Vander Mause, Michael L. Olson, Sara Yousef, Jens Panse, Yasmina Abdiche, K. David Li, Rodney R. Miles, William Matsui, Alana L. Welm, Djordje Atanackovic
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
CD229 is expressed on the surface of multiple myeloma cells, as well as B and T lymphocytes. Here, the authors engineer CD229-specific CAR T cells and, using patient samples and mouse models, show that treatment with these cells reduces tumour burden
Externí odkaz:
https://doaj.org/article/4e432057e84c4bb2853dee941535a21e
Autor:
Adam M Kase, Catherine Bullock, Ricardo Parrondo, Muhamad Alhaj Moustafa, Madiha Iqbal, K David Li, Ephraim Parent, Han Tun
Publikováno v:
Blood and Lymphatic Cancer: Targets and Therapy. 12:17-21
Autor:
Jessica Corean, K. David Li
Publikováno v:
Case Reports in Hematology, Vol 2018 (2018)
Anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK+ LBCL) is a very rare and aggressive subtype of diffuse large B-cell lymphoma characterized by ALK rearrangement. Immunophenotypically, the tumor cells are typically negative for common B
Externí odkaz:
https://doaj.org/article/afc4b37468e64c5abb774185a0b4cb78
Autor:
Sandra D. Scherer, Alana L. Welm, Sara Yousef, Tim Luetkens, Rodney R. Miles, Yasmina Noubia Abdiche, Sabarinath Venniyil Radhakrishnan, K. David Li, Djordje Atanackovic, Erica R. Vander Mause, William Matsui, Patricia Davis, Jens Panse, Michael L. Olson
Publikováno v:
Journal of the National Comprehensive Cancer Network. 18:YIA20-003
Autor:
Jay Patel, Philippe Szankasi, Jonathan A. Schumacher, K. David Li, Mohamed E. Salama, Anna P. Matynia, Xinjie Xu, Elaine P.S. Gee, Ashini Bolia, Michael Liew, Todd W. Kelley
Publikováno v:
Journal of Hematopathology. 12:121-133
Balanced translocations have diagnostic and prognostic value in B-cell lymphoproliferative disorders (LPDs). Most of these translocations involve the juxtaposition of a strong immunoglobulin (Ig) enhancer to proto-oncogenes, such as BCL2, BCL6, and M
Autor:
Jens Panse, Sandra D. Scherer, Rodney R. Miles, William Matsui, Michael Olson, Yasmina Noubia Abdiche, Erica R. Vander Mause, Alana L. Welm, Patricia Davis, K. David Li, Sabarinath Venniyil Radhakrishnan, Sara Yousef, Djordje Atanackovic, Tim Luetkens
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
Multiple myeloma (MM) is a plasma cell malignancy and most patients eventually succumb to the disease. Chimeric antigen receptor (CAR) T cells targeting B-Cell Maturation Antigen (BCMA) on MM cells have shown high-response rates, but limited durabili
Autor:
K. David Li, Mohamed E. Salama
Publikováno v:
Surgical Pathology Clinics. 9:177-187
This article highlights the most common morphologic features identified in the bone marrow after chemotherapy for hematologic malignancies, growth-stimulating agents, and specific targeted therapies. The key is to be aware of these changes while revi
Autor:
Ron Thomason, Lorinda Soma, Sindhu Cherian, Jonathan R. Fromm, Kerstin L. Edlefsen, Jing Du, Amanda Moklebust, K David Li
Publikováno v:
American Journal of Clinical Pathology. 154:S1-S1
Background B-lymphoblastic leukemia (BLL) is a B lineage neoplasm that expresses typical immature B cell markers, but may also express myeloid-associated antigens. Myeloperoxidase (MPO) is a heme-containing peroxidase, which has been used as the sing
Autor:
Mohamed E. Salama, Michael Liew, Anna P. Matynia, Philippe Szankasi, K. David Li, Todd W. Kelley, Jonathan A. Schumacher
Publikováno v:
Archives of pathologylaboratory medicine. 143(1)
Context.—B-cell lymphomas exhibit balanced translocations that involve immunoglobulin loci and result from aberrant V(D)J recombination, class switch recombination, or somatic hypermutation. Although most of the breakpoints in the immunoglobulin lo
Publikováno v:
Fetal and pediatric pathology. 36(2)
There is a known association of primary nonseminomatous mediastinal germ cell tumors (NSMGCT) and hematologic malignancy in younger males not linked to treatment. When combined these two rare entities convey a very poor prognosis. Here we report a 16