Zobrazeno 1 - 10
of 16
pro vyhledávání: '"K D Keef"'
Publikováno v:
The Journal of physiology. 596(22)
KEY POINTS: Inhibitory neuromuscular transmission (NMT) was compared in the internal anal sphincter (IAS) and rectum of the Cynomolgus monkey, an animal with high gene sequence identity to humans. Nitrergic NMT was present in both muscles while purin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9813692f239185b58fe6b7d691addb2b
https://pubmed.ncbi.nlm.nih.gov/30198065
https://pubmed.ncbi.nlm.nih.gov/30198065
Publikováno v:
Neurogastroenterology and Motility. 17:575-584
Adenosine triphosphate (ATP) mediates excitatory junction potentials through P2X receptors in many smooth muscles. However, relatively little is known about postjunctional intestinal P2X receptors. We examined the effect of exogenous ATP on circular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8797d2f3e905987f45935ec76b64921a
https://doi.org/10.1111/j.1365-2982.2005.00670.x
https://doi.org/10.1111/j.1365-2982.2005.00670.x
Publikováno v:
The Journal of physiology. 592(17)
The internal anal sphincter (IAS) develops tone and is important for maintaining a high anal pressure while tone in the rectum is less. The mechanisms responsible for tone generation in the IAS are still uncertain. The present study addressed this qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9de8fa3316d9a20306d5ccaee6f9f6f1
https://pubmed.ncbi.nlm.nih.gov/24951622
https://pubmed.ncbi.nlm.nih.gov/24951622
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 75:1116-1122
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c2c914e419584f7fdb34c35218094f0
https://doi.org/10.1139/y97-143
https://doi.org/10.1139/y97-143
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 24(1)
Intramuscular interstitial cells of Cajal (ICC-IM) have been shown to participate in nitrergic neuromuscular transmission (NMT) in various regions of the gastrointestinal (GI) tract, but their role in the internal anal sphincter (IAS) is still uncert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b44b0af4957c2b1ff1e29ac1dae79920
https://pubmed.ncbi.nlm.nih.gov/22074497
https://pubmed.ncbi.nlm.nih.gov/22074497
Publikováno v:
The Journal of physiology. 531(Pt 1)
1. Previous studies have shown that purified G protein alphas and betagamma subunits stimulate vascular L-type Ca2+ channels through protein kinase A and C (PKA and PKC), respectively. The present study tested whether activation of endogenous G prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4de4b4ed11034083c15a0c5cf8be8a9e
https://pubmed.ncbi.nlm.nih.gov/11179395
https://pubmed.ncbi.nlm.nih.gov/11179395
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(2)
The characteristics of the Ca(2+) entry pathways that are activated by protein kinase C (PKC) in canine splenic artery were investigated. Phorbol 12, 13-dibutyrate (PDB) contracted tissues and increased Ca(2+) influx. PDB-induced contraction was redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a3edb984815a15fcf51359f0d1603fb
https://pubmed.ncbi.nlm.nih.gov/10525105
https://pubmed.ncbi.nlm.nih.gov/10525105
Publikováno v:
British journal of pharmacology. 126(7)
1. The gastric adaptation reflex is activated by the release of non-adrenergic, non-cholinergic (NANC) inhibitory transmitters, including nitric oxide (NO) and vasoactive intestinal polypeptide (VIP). The role of NO in this reflex is not disputed, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::493c0a244cb2970c294ee1c34006aac8
https://pubmed.ncbi.nlm.nih.gov/10323585
https://pubmed.ncbi.nlm.nih.gov/10323585
Publikováno v:
Canadian journal of physiology and pharmacology. 75(9)
Previous studies have suggested that delayed rectifier K+ (Kdr) channels contribute to the control of membrane potential in vascular smooth muscle. To explore this hypothesis further, we investigated the characteristics of Kdr channels in the negativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f23bea7669cfdd7eb7a241d4f2963371
https://pubmed.ncbi.nlm.nih.gov/9365823
https://pubmed.ncbi.nlm.nih.gov/9365823
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 260(2)
Purinergic relaxation and hyperpolarization was investigated in the isolated guinea pig coronary artery (GPCA) and compared to purinergic relaxation in the rabbit coronary artery (RCA). Vessels were contracted with the histamine H1 receptor agonist 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f480f5916dbf561f776e0cdaedb8341
https://pubmed.ncbi.nlm.nih.gov/1738109
https://pubmed.ncbi.nlm.nih.gov/1738109