Zobrazeno 1 - 10
of 34
pro vyhledávání: '"K D, Philipson"'
Autor:
K D, Philipson
Publikováno v:
Trends in cardiovascular medicine. 2(1)
The sarcolemmal Na(+)-Ca(2+) exchanger is the dominant myocardial Ca(2+) efflux mechanism and has a central role in the regulation of contractility. Physiologic and molecular advances in Na(+)-Ca(2+) exchange research have led a resurgence of interes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8964a316d3143ace74e384195595207f
https://pubmed.ncbi.nlm.nih.gov/21239282
https://pubmed.ncbi.nlm.nih.gov/21239282
Publikováno v:
American Journal of Physiology-Cell Physiology. 265:C748-C756
We used a panel of monoclonal antibodies raised against the canine cardiac Na(+)-Ca2+ exchanger expressed in Sf9 insect cells to analyze the immunoreactive domains and the topological organization of this membrane protein. Antibodies, which reacted s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbea98e09662ecd8b8745c2b87725cbb
https://doi.org/10.1152/ajpcell.1993.265.3.c748
https://doi.org/10.1152/ajpcell.1993.265.3.c748
Publikováno v:
The Journal of biological chemistry. 276(22)
The Na(+)-Ca(2+) exchanger has nine transmembrane segments, with a large cytoplasmic loop between the fifth and sixth transmembrane segments. The protein was split within the cytoplasmic loop into two domains consisting of the first five transmembran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2276094af19a6b31885ffa04e81f26d
https://pubmed.ncbi.nlm.nih.gov/11274218
https://pubmed.ncbi.nlm.nih.gov/11274218
Autor:
B, Linck, P, Bokník, S, Huke, U, Kirchhefer, J, Knapp, H, Lüss, F U, Müller, J, Neumann, Z, Tanriseven, U, Vahlensieck, H A, Baba, L R, Jones, K D, Philipson, W, Schmitz
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(2)
Overexpression of calsequestrin (CSQ) induces severe cardiac hypertrophy, whereas overexpression of Na(+)-Ca(2+) exchanger (NCX) does not affect cardiac weight. To investigate a possible beneficial effect of NCX in hypertrophy, we produced transgenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0255804083245a94e131886f4aa06ca3
https://pubmed.ncbi.nlm.nih.gov/10900244
https://pubmed.ncbi.nlm.nih.gov/10900244
Autor:
H, Porzig, K D, Philipson
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8af35d20f54f577629546b7f4e972737
https://pubmed.ncbi.nlm.nih.gov/8959721
https://pubmed.ncbi.nlm.nih.gov/8959721
Publikováno v:
The Journal of biological chemistry. 269(36)
The cardiac sarcolemmal Na(+)-Ca2+ exchanger transports Na+ and Ca2+ but is also regulated by Ca2+ at a high affinity binding site. A large intracellular, hydrophilic loop of the exchanger has been suggested to contain the Ca(2+)-binding regulatory d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66211e60dfecd572041f4faf448388c7
https://pubmed.ncbi.nlm.nih.gov/8077237
https://pubmed.ncbi.nlm.nih.gov/8077237
Autor:
Z, Li, S, Matsuoka, L V, Hryshko, D A, Nicoll, M M, Bersohn, E P, Burke, R P, Lifton, K D, Philipson
Publikováno v:
The Journal of biological chemistry. 269(26)
The Na(+)-Ca2+ exchanger is an important regulator of cellular Ca2+ levels, and one isoform of this transporter, NCX1, has been cloned previously (Nicoll, D.A., Longoni, S., and Philipson, K.D. (1990) Science 250, 562-565). We now report the cloning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec4c7c7201327f8ec24c38d0cdec2425
https://pubmed.ncbi.nlm.nih.gov/8021246
https://pubmed.ncbi.nlm.nih.gov/8021246
Publikováno v:
The Journal of biological chemistry. 268(16)
Na+-Ca2+ exchange is the major pathway of Ca2+ efflux during excitation-contraction coupling in cardiac muscle. The Na+-Ca2+ exchanger is present in cardiac transverse tubules with an apparent high density (Frank, J.S., Mottino, G., Reid, D., Molday,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab7c081af44fdef23eab84f4ab093f4d
https://pubmed.ncbi.nlm.nih.gov/8505285
https://pubmed.ncbi.nlm.nih.gov/8505285
Autor:
K D, Philipson, D A, Nicoll
Publikováno v:
International review of cytology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::690e17d6b77ab3c77e465b61206829ad
https://pubmed.ncbi.nlm.nih.gov/8486471
https://pubmed.ncbi.nlm.nih.gov/8486471
Publikováno v:
Society of General Physiologists series. 48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa7983b0f71c8223ed9b0cf901c03a7e
https://pubmed.ncbi.nlm.nih.gov/8503043
https://pubmed.ncbi.nlm.nih.gov/8503043