Zobrazeno 1 - 10
of 776
pro vyhledávání: '"K Clare"'
Autor:
Maud Dumoux, Thomas Glen, Jake LR Smith, Elaine ML Ho, Luis MA Perdigão, Avery Pennington, Sven Klumpe, Neville BY Yee, David Andrew Farmer, Pui YA Lai, William Bowles, Ron Kelley, Jürgen M Plitzko, Liang Wu, Mark Basham, Daniel K Clare, C Alistair Siebert, Michele C Darrow, James H Naismith, Michael Grange
Publikováno v:
eLife, Vol 12 (2023)
Serial focussed ion beam scanning electron microscopy (FIB/SEM) enables imaging and assessment of subcellular structures on the mesoscale (10 nm to 10 µm). When applied to vitrified samples, serial FIB/SEM is also a means to target specific structur
Externí odkaz:
https://doaj.org/article/fbc6e73bd5344bb9801714368bad32dd
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Dynamin mediates the fission of vesicles during endocytosis. Here, the authors report the cryoEM structure of a super-constricted two-start dynamin 1 filament- one of the two known helical forms of dynamin, with insights into the molecular mechanisms
Externí odkaz:
https://doaj.org/article/24778749667c43f38f4e3d2293cb02c0
Autor:
Jiandong Huo, Halina Mikolajek, Audrey Le Bas, Jordan J. Clark, Parul Sharma, Anja Kipar, Joshua Dormon, Chelsea Norman, Miriam Weckener, Daniel K. Clare, Peter J. Harrison, Julia A. Tree, Karen R. Buttigieg, Francisco J. Salguero, Robert Watson, Daniel Knott, Oliver Carnell, Didier Ngabo, Michael J. Elmore, Susan Fotheringham, Adam Harding, Lucile Moynié, Philip N. Ward, Maud Dumoux, Tessa Prince, Yper Hall, Julian A. Hiscox, Andrew Owen, William James, Miles W. Carroll, James P. Stewart, James H. Naismith, Raymond J. Owens
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Neutralizing nanobodies (Nb) are of considerable interest as therapeutic agents for COVID-19 treatment. Here, the authors functionally and structurally characterize Nbs that bind with high affinity to the receptor binding domain of the SARS-CoV-2 spi
Externí odkaz:
https://doaj.org/article/d505e344aed84336a3d7f7d369c5238a
Autor:
Talya S. Levitz, Miriam Weckener, Ivan Fong, James H. Naismith, Catherine L. Drennan, Edward J. Brignole, Daniel K. Clare, Michele C. Darrow
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The specimen preparation process is a key determinant in the success of any cryo electron microscopy (cryoEM) structural study and until recently had remained largely unchanged from the initial designs of Jacques Dubochet and others in the 1980s. The
Externí odkaz:
https://doaj.org/article/b2580e688193450db37856df424dbc9b
Autor:
Geoff Sutton, Dapeng Sun, Xiaofeng Fu, Abhay Kotecha, Corey W. Hecksel, Daniel K. Clare, Peijun Zhang, David I. Stuart, Mark Boyce
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Reoviridae undergo a complex assembly pathway in the host cell. Here the authors use cryo-electron tomography to visualize the assembly stages of mammalian orthoreovirus revealing a single shelled intermediate with gross similarity to an early assemb
Externí odkaz:
https://doaj.org/article/08db4ba63126425986073b664fcf412b
Publikováno v:
In Journal of Plastic, Reconstructive & Aesthetic Surgery June 2019 72(6):941-945
Autor:
Kamel El Omari, Sai Li, Abhay Kotecha, Thomas S. Walter, Eduardo A. Bignon, Karl Harlos, Pentti Somerharju, Felix De Haas, Daniel K. Clare, Mika Molin, Felipe Hurtado, Mengqiu Li, Jonathan M. Grimes, Dennis H. Bamford, Nicole D. Tischler, Juha T. Huiskonen, David I. Stuart, Elina Roine
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Lipid membrane fusion is an essential function in many biological processes but little is known about membrane fusion in prokaryotes. The authors here study how haloarchaeal pleomorphic viruses (HRPVs) infect archaeal hosts. The structure-function an
Externí odkaz:
https://doaj.org/article/31855e58b674426b946b1b8cc027fb2e
Autor:
Andrew R Pugh, Cecilia M Romo, Graeme K Clare, Nicolas Meurisse, Martin K F Bader, Stephen M Pawson
Publikováno v:
Environmental Entomology. 52:56-66
Hylurgus ligniperda (F.) and Hylastes ater (Paykull) are secondary bark beetles that have successfully spread beyond their native range, particularly into Pinus spp. plantations in the Southern Hemisphere. They feed on the phloem and cambial regions
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