Zobrazeno 1 - 10
of 75
pro vyhledávání: '"K Charrier"'
Autor:
M B Glaccum, K L Stocking, K Charrier, J L Smith, C R Willis, C Maliszewski, D J Livingston, J J Peschon, P J Morrissey
Publikováno v:
The Journal of Immunology. 159:3364-3371
IL-1 alpha and IL-1 beta bind to receptors termed the type I and type II IL-1 receptors. The type I IL-1 receptor is responsible for specific signaling, while the type II IL-1 receptor functions as a nonsignaling decoy receptor. To determine the effe
Publikováno v:
The Journal of Immunology. 154:2678-2686
Severe combined immunodeficient (SCID) mice injected with co-isogenic CD4+/CD45RBhigh lymph node T cells from normal donors develop a wasting disease that is caused by hyperplasia of the intestinal epithelium. SCID mice injected with purified lymph n
Autor:
P J Morrissey, K Charrier
Publikováno v:
The Journal of Immunology. 153:212-219
Administration of a single dose of IL-1 alpha to various strains of mice approximately 16 h before a lethal infection with Salmonella typhimurium resulted in a significant augmentation of survival in most Ityr, but in no Itys strains of mice. Lower n
Publikováno v:
The Journal of Immunology. 147:561-568
Normal mice were injected with IL-7 (500 ng, twice daily) for various periods of time up to 6 days and the cellularity and phenotypic composition of the thymus, spleen, lymph node, and bone marrow was assessed. After 6 days of treatment, significant
Autor:
P J Morrissey, K Charrier
Publikováno v:
The Journal of Immunology. 144:557-561
Ity resistant A/J mice were challenged with a lethal dose (2 x 10(3) organisms) of Salmonella typhimurium. Infected mice treated with 1 microgram of GM-CSF twice daily showed increased median survival time and had a higher survival fraction than untr
Publikováno v:
Infection and Immunity. 63:3196-3198
Interleukin-1 alpha (IL-1 alpha) or tumor necrosis factor alpha (TNF-alpha) administered prior to infection with Salmonella typhimurium increases survival in mice that are Ityr, not in susceptible Lpsd or Itys mice. Combined IL-1 alpha and TNF-alpha
Autor:
P J Morrissey, K Charrier
Publikováno v:
Infection and Immunity. 59:4729-4731
Interleukin-1 (IL-1) treatment of C3H/HeN and C3H/HeJ mice prior to infection with Salmonella typhimurium increased the survival fraction only in C3H/HeN mice. IL-1 administration after infection resulted in a significant increase in mean survival ti
TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation
Autor:
J J, Peschon, D S, Torrance, K L, Stocking, M B, Glaccum, C, Otten, C R, Willis, K, Charrier, P J, Morrissey, C B, Ware, K M, Mohler
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(2)
The pleiotropic activities of the potent proinflammatory cytokine TNF are mediated by two structurally related, but functionally distinct, receptors, p55 and p75, that are coexpressed on most cell types. The majority of biologic responses classically
Autor:
K, Brasel, H J, McKenna, P J, Morrissey, K, Charrier, A E, Morris, C C, Lee, D E, Williams, S D, Lyman
Publikováno v:
Blood. 88(6)
We have investigated the effects of in vivo treatment with flt3 ligand (FL) on murine hematopoiesis, including mobilization of progenitors into the peripheral blood (PB). Mice were injected once daily with 10 micrograms recombinant human FL for 15 da
Autor:
K. Charrier, P.J. Morrissey
Publikováno v:
Research in immunology. 145(5)
Summary SCID mice injected with coisogenic CD4+/ CD45RBhi lymph node T cells from normal donors develop a wasting disease that is due to hyperplasia of the intestinal epithelium. SCID mice injected with purified lymph node CD4+ T cells or CD4+/CD45RB