Zobrazeno 1 - 10
of 254
pro vyhledávání: '"K Bosslet"'
Autor:
Helmut Friess, Hans G. Beger, R. Kübel, G. Schulz, K. Bosslet, Markus W. Büchler, Peter Malfertheiner
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 113:374-380
In the course of a phase I study monoclonal antibody BW 494 was injected i.v. at a dose of 180-340 mg to 18 patients with advanced ductal pancreatic carcinoma. The murine IgG1-antibody is directed against a pancreatic carcinoma-associated glycoprotei
Publikováno v:
Experimental and Toxicologic Pathology. 52:277-285
Antibodies against two major gangliosides detected in human brain and brain tumors--Glac2 (GD3) and Gtri2 (GD2)--were tested by immunohistochemistry in an unselected sample of intracranial tumors during the years 1986 through 1991. Two groups emerged
Autor:
H-E Gabbert, K. Bosslet, Hartmut M. Rabes, M. F. Rajewsky, H. Grunicke, G. Eisenbrand, Werner K. Lutz, Martin R. Schneider, G. Bornkamm, P von Hoegen, G. Brandner
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 121:683-690
Biochemical properties of recombinant human β-glucuronidase synthesized in baby hamster kidney cells
Publikováno v:
Biochemical Journal. 301:821-828
The cDNA sequence encoding human beta-glucuronidase [Oshima, Kyle, Miller, Hoffmann, Powell, Grubb, Sly, Troplak, Guise and Gravel (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 685-689] was expressed in baby hamster kidney (BHK) cells. After purification
Autor:
Norbert Madry, K. Bosslet, Kai Hammer, Markus W. Büchler, Alexander Weber, Bernhard Dr Auerbach, Peter Malfertheiner, Helmut Friess, Sabine Greiner, Hans G. Beger
Publikováno v:
International Journal of Cancer. 53:759-763
In 59 patients with ductal pancreatic cancer the monoclonal antibody (MAb) BW 494, which detects the CA 494 glycoprotein antigen, was analyzed in comparison with the reference tumor markers CA 19-9 and CEA. Eighty-one patients with non-pancreatic mal
Publikováno v:
Experimental and Toxicologic Pathology. 44:317-324
Summary Two monoclonal antibodies (mabs) were raised against ganglioside GD2 (Gtri2) and tested on human intracranial tumors and normal brain by immunohistochemical methods both in frozen and paraffin embedded sections. In normal brain structures, as
Publikováno v:
British Journal of Cancer
A fusion protein consisting of the humanised Fab fragment of the anti CEA MAb BW 431 and the human beta-glucuronidase was expressed in BHK cells. Functional testing revealed that the specificity and avidity of the humanised V region was similar to th
Autor:
P. Hermentin, G. Seemann, H.H. Sedlacek, A. Bruynck, M. Magerstaedt, L. Kuhlmann, K. Bosslet, A. Steinstraesser, A. Schwarz
Publikováno v:
British Journal of Cancer
A two phase radioimmunotherapy based on bispecific MAbs in which one arm recognises a tumour antigen and the other a radiolabelled chelate, may prove more effective in the treatment of carcinomas than currently available immunotherapies. To establish
Publikováno v:
Consulting ISBN: 9783642626562
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d028e301978fa57d2b535218b81c6be6
https://doi.org/10.1007/978-3-642-56459-8_7
https://doi.org/10.1007/978-3-642-56459-8_7
Publikováno v:
Consulting ISBN: 9783642980800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e6858722eb9c86e86acfd35e07ec32c
https://doi.org/10.1007/978-3-642-98079-4_8
https://doi.org/10.1007/978-3-642-98079-4_8