Zobrazeno 1 - 10
of 23
pro vyhledávání: '"K B, Delclos"'
Publikováno v:
Biomaterials. 21:1947-1957
The implantation of biomaterials elicits a host response that influences the long-term behavior of implanted medical devices. This foreign body response is governed by cells of the immune system. Because sexual dimorphism in the immune system is well
Publikováno v:
Environmental and Molecular Mutagenesis. 35:336-342
In this study, the rodent air pouch model was used to examine the production and processing of oxidative DNA damage in two strains of rats commonly used in toxicity testing. An inflammatory response was induced by injecting zymosan A (50 mg) into an
Autor:
K B, Delclos, Retha, Newbold
Publikováno v:
Toxicity report series. (79)
Genistein is a naturally occurring isoflavone that interacts with estrogen receptors and multiple other molecular targets. Human exposure to genistein is predominantly through consumption of soy products, including soy-based infant formula and dietar
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 82(2)
The adult rat brain develops through an interplay of neuronal proliferation and programmed cell death. Steroid hormones and growth factors may alter the balance between these competing processes. "Endocrine disrupters" (EDs) may also alter brain deve
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 62(1)
para-Nonylphenol (NP; CAS #84852‐15‐3), an alkylphenol with a 9-carbon olefin side chain, is widely used in the manufacture of nonionic surfactants, lubricant additives, polymer stabilizers, and antioxidants. Due to its wide commercial use and pu
Publikováno v:
Neurotoxicology. 21(6)
The phytoestrogen and principal isoflavone in soy, genistein, has adverse effects on reproductive physiology in rodents. Since physiology and behavior are both sensitive to perturbations by estrogens, genistein may produce behavioral alterations as w
Publikováno v:
Environmental and molecular mutagenesis. 35(4)
In this study, the rodent air pouch model was used to examine the production and processing of oxidative DNA damage in two strains of rats commonly used in toxicity testing. An inflammatory response was induced by injecting zymosan A (50 mg) into an
Publikováno v:
Rapid communications in mass spectrometry : RCM. 14(8)
Soy isoflavones are the subject of many investigations in experimental animals and humans regarding possible modulation of endocrine activity and chemoprevention of carcinogenesis. Genistein and daidzein, the principal biologically active isoflavones
Publikováno v:
Cancer research. 56(9)
The environmental contaminant 6-nitrochrysene (6-NC) has been shown to induce adenomas and adenocarcinomas in the colons of rats. The present study aimed at providing a better understanding of mechanisms that are responsible for this effect. Three fe
Publikováno v:
IARC scientific publications. (124)
Carcinogenic arylamines and nitroaromatic hydrocarbons are chemicals that present occupational health hazards and share pathways of metabolic activation. The 32P-postlabelled DNA adducts formed in Chinese hamster ovary (CHO) cells treated with metabo