Zobrazeno 1 - 10
of 33
pro vyhledávání: '"K Adam, Bohnert"'
Publikováno v:
Fly, Vol 17, Iss 1 (2023)
Valosin-containing protein (VCP) is a versatile and ubiquitously expressed AAA+ ATPase that regulates multiple stages of Drosophila spermatogenesis. While VCP has documented roles in mitotic spermatogonia and meiotic spermatocytes, it is also highly
Externí odkaz:
https://doaj.org/article/50f9272c03964b54956385b1d57f5899
Publikováno v:
Biology Open, Vol 12, Iss 5 (2023)
Externí odkaz:
https://doaj.org/article/7849e957faf0467fbac18a3d692520f3
Autor:
K. Adam Bohnert, Alyssa E. Johnson
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Lysosomes are acidic, membrane-bound organelles that play essential roles in cellular quality control, metabolism, and signaling. The lysosomes of a cell are commonly depicted as vesicular organelles. Yet, lysosomes in fact show a high degree of ultr
Externí odkaz:
https://doaj.org/article/c67a877348ef40d2a0f3fbddaa2cfae2
Autor:
Madhuja Samaddar, Jérôme Goudeau, Melissa Sanchez, David H Hall, K Adam Bohnert, Maria Ingaramo, Cynthia Kenyon
Publikováno v:
eLife, Vol 10 (2021)
Somatic cells age and die, but the germ-cell lineage is immortal. In Caenorhabditis elegans, germline immortality involves proteostasis renewal at the beginning of each new generation, when oocyte maturation signals from sperm trigger the clearance o
Externí odkaz:
https://doaj.org/article/fc5f2a8480a34f0d98baf157cabd6769
Autor:
K. Adam Bohnert, Tyler J. Butsch, Dominique A Dolese, Alyssa E. Johnson, Bhaswati Ghosh, Matthew P Junot
Publikováno v:
Autophagy. 18:1522-1533
Organelle-specific autophagy directs degradation of eukaryotic organelles under certain conditions. Like other organelles, peroxisomes are subject to autophagic turnover at lysosomes. However, peroxisome autophagy (pexophagy) has yet to be analyzed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1724e1c93b277ed41c50197170586d
https://doi.org/10.1080/15548627.2021.1990647
https://doi.org/10.1080/15548627.2021.1990647
Valosin-containing protein (VCP) binds and extracts ubiquitinated cargo to regulate protein homeostasis. While VCP has been studied primarily in aging and disease contexts, it also affects germline development. However, the precise molecular function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6338bce3f07cf531a80c1fe43f63a753
https://doi.org/10.1101/2022.12.21.521492
https://doi.org/10.1101/2022.12.21.521492
Publikováno v:
J Exp Biol
Sex-specific differences in animal behavior commonly reflect unique reproductive interests. In the nematode Caenorhabditis elegans, hermaphrodites can reproduce without a mate and thus prioritize feeding to satisfy the high energetic costs of reprodu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e57f5b1f7b04b016077cd8af15a4c49
https://doi.org/10.1242/jeb.244282
https://doi.org/10.1242/jeb.244282
Autor:
Tyler J. Butsch, Suman Das, Eric D. Eymard, Brennan M. Mercola, Cara D. Ramos, Alyssa E. Johnson, K. Adam Bohnert, Tatiana V. Villalobos, Sanaa Alam, Bhaswati Ghosh
Dietary restriction promotes longevity via autophagy activation. However, changes to lysosomes underlying this effect remain unclear. Using the nematode Caenorhabditis elegans, we show that induction of autophagic tubular lysosomes, which occurs upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e28edbf06483dd692c95d840eeb5d79
https://doi.org/10.1101/2021.10.28.466256
https://doi.org/10.1101/2021.10.28.466256
Autor:
Dominique A, Dolese, Matthew P, Junot, Bhaswati, Ghosh, Tyler J, Butsch, Alyssa E, Johnson, K Adam, Bohnert
Publikováno v:
Autophagy. 18(7)
Organelle-specific autophagy directs degradation of eukaryotic organelles under certain conditions. Like other organelles, peroxisomes are subject to autophagic turnover at lysosomes. However, peroxisome autophagy (pexophagy) has yet to be analyzed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4be7a6ae90983e98c6a8bb45a962a53d
https://pubmed.ncbi.nlm.nih.gov/34689720
https://pubmed.ncbi.nlm.nih.gov/34689720
Publikováno v:
J Gerontol A Biol Sci Med Sci
Like other biological processes, aging is not random but subject to molecular control. Natural products that modify core metabolic parameters, including fat content, may provide entry points to extend animal life span and promote healthy aging. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d5a248d5f424c3c339a0ef251d1c62
https://pubmed.ncbi.nlm.nih.gov/35167659
https://pubmed.ncbi.nlm.nih.gov/35167659