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P646 Relative association of bowel urgency clinically meaningful improvement and bowel urgency remission versus stool frequency remission and rectal bleeding remission with improvement in Work Productivity and Activity Impairment Scores in patients with moderately-to-severely active Ulcerative Colitis: An analysis from LUCENT-1 and LUCENT-2 Phase 3 clinical trials

Autor: B E Sands, B G Feagan, T H Gibble, A Keohane, W J Eastman, K A Traxler, S Schreiber, V Jairath, A Armuzzi

Publikováno v: Journal of Crohn's and Colitis. 17:i775-i777

Background Bowel urgency is increasingly recognized as a common and impactful symptom in patients with Ulcerative Colitis (UC).1 However, there are limited data exploring the relationship of bowel urgency with work productivity. We examined the relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::253fe4eb375d8391846faa578b629c60
https://doi.org/10.1093/ecco-jcc/jjac190.0776

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A31 MIRIKIZUMAB IMPROVES QUALITY OF LIFE IN MODERATELY-TO-SEVERELY ACTIVE UC: IMPROVEMENT IN IBDQ SCORES IN PARTICIPANTS OF LUCENT-1 AND LUCENT-2 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 3 TRIALS

Autor: B E Sands, B Feagan, T H Gibble, K A Traxler, N Morris, X Li, S Schreiber, V Jairath, A Armuzzi, J Jones

Publikováno v: Journal of the Canadian Association of Gastroenterology. 6:16-17

Background The inflammatory bowel disease questionnaire (IBDQ) is a measure of health-related quality of life (QoL), with higher scores indicating greater QoL. In a prior phase 2 study (NCT02589665), mirikizumab, an anti-IL23p19 antibody, demonstrate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9facfd47f5d8a80c01cd5d30bde93cf0
https://doi.org/10.1093/jcag/gwac036.031

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