Zobrazeno 1 - 10
of 31
pro vyhledávání: '"K A McDonough"'
Publikováno v:
Infection and Immunity. 61:2763-2773
Central to understanding the pathogenesis of tuberculosis is the interaction between the pathogen and mononuclear phagocytes. A key question about that interaction is whether Mycobacterium tuberculosis exerts an effect on phagolysosome fusion. We hav
Autor:
K B, McDONOUGH
Publikováno v:
Wisconsin medical journal. 46(7)
Autor:
J A, Ismail, K H, McDonough
Publikováno v:
Canadian journal of physiology and pharmacology. 79(3)
Myocardial function is impaired 24 h after the induction of sepsis, however, recovery of left ventricular (LV) function after 35 min of global ischemia is complete. The mechanisms by which this protection occurs are unknown. Ischemic preconditioning,
Publikováno v:
Alcoholism, clinical and experimental research. 22(4)
Insulin-like growth factor (IGF)-I is a potent anabolic agent that plays an important role in regulating muscle protein balance. Alterations in one or more of the various components of the IGF system may be in part responsible for the muscle wasting
Autor:
J L, Roglieri, R, Futterman, K L, McDonough, G, Malya, K R, Karwath, D, Bowman, J, Skelly, S W, Warburton
Publikováno v:
The American journal of managed care. 3(12)
This study is part of a planned 24-month, multicenter, longitudinal comparison of a comprehensive congestive heart failure (CHF) disease management program and was designed to determine effectiveness after 12 months of implementation. The impact of i
Autor:
K H, McDonough
Publikováno v:
Alcoholism, clinical and experimental research. 21(5)
We have previously demonstrated that chronic alcohol consumption (8 to 10 weeks with ethanol as 36% of the caloric intake) does not exacerbate the effects of ischemia reperfusion injury on the heart. In those same studies, however, Gram-negative seps
Autor:
Y Kress, K A McDonough
Publikováno v:
Infection and immunity. 63(12)
Dissemination of viable tubercle bacilli from the lung is a critical event in the establishment of Mycobacterium tuberculosis infection. We examined the possibility that M. tuberculosis bacteria could infect and damage lung epithelial cells to determ
Publikováno v:
American journal of veterinary research. 53(5)
A model of bovine pneumonic pasteurellosis, using an indwelling bronchial catheter for inoculation and subsequent lavage of a single main stem bronchus of the lung, was evaluated in a preliminary efficacy trial of an experimental therapeutic compound
Publikováno v:
Journal of developmental physiology. 14(5)
We investigated mechanical and metabolic responses in isolated, isovolumically-beating, pig hearts (n = 7), 12 h to 2 days of age; subjected to hypoxia followed by reoxygenation. Hearts were perfused with an erythrocyte-enriched (hematocrit approxima
Mechanical function and fatty acid oxidation in the neonatal pig heart with ischemia and reperfusion
Publikováno v:
Journal of developmental physiology. 14(5)
We investigated mechanical function and exogenous fatty acid oxidation in neonatal pig hearts subjected to ischemia, followed by reperfusion. Isolated, isovolumically-beating hearts, from pigs 12 h to 2 days of age, were perfused with an erythrocyte-