Zobrazeno 1 - 10
of 22
pro vyhledávání: '"K A Koshechkin"'
Publikováno v:
RUDN Journal of Medicine, Vol 0, Iss 3, Pp 10-13 (2008)
Methotrexate is one of the most effective and widely used cytostatic drugs. However as all antineoplastic drugs it has very low therapeutic index and high toxicity. Kinetic parameters (rate constants, half-times of restoration and extreme values of c
Externí odkaz:
https://doaj.org/article/2d8fcebc621f47ccbc59d5ef20b07af7
Publikováno v:
Безопасность и риск фармакотерапии, Vol 11, Iss 4, Pp 409-422 (2023)
Scientific relevance. Medication adherence is an important condition for effective and safe treatment. The adherence of patients to prescriptions is tracked by assessing their condition, counting the pills taken, and using other indirect methods. Dig
Externí odkaz:
https://doaj.org/article/5159efa53bb247e2b7d3386add551b0c
Autor:
K. A. Koshechkin, Yu. V. Olefir
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 9, Iss 3, Pp 191-196 (2019)
Improvement of drug supply is one of the key factors contributing to the quality of medical services, but it cannot be achieved without introduction of digital technologies. This is a complex task that requires a systematic approach which includes pl
Externí odkaz:
https://doaj.org/article/d81e6c63b87a419ba7eae94f76107347
Publikováno v:
Clinical and experimental thyroidology. 18:17-26
The article describes a method for assessing the malignancy potential of thyroid nodules and their stratification according to the European Thyroid Imaging And Reporting Data System (Eu-TIRADS) scale based on ultrasound diagnostic images using an art
Publikováno v:
REMEDIUM. 26:255-261
The article describes current approaches to the digital transformation of pharmaceutical companies, taking into account the specifics of the requirements of import substitution of software for domestic production systems. Based on publications and op
Autor:
K. А. Koshechkin
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 8, Iss 2, Pp 103-108 (2018)
This article describes the results of Laboratory Information Management System implementation in an expert institution dealing with medicines evaluation. The purpose of the study was to evaluate the feasibility of providing digital support to the lab
Externí odkaz:
https://doaj.org/article/e31c3e8cd8f24c2aad6a4f51f52c3c2d
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 0, Iss 1, Pp 49-52 (2018)
Nternational practices comprise integrated common approaches to validation of information systems, used in pharmaceutical industry by various organizations and that affect the results of their work. The purpose ofvalidation is to assure that the resu
Externí odkaz:
https://doaj.org/article/4be77973a1de423d9d2ef8e33ed999e5
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 0, Iss 3, Pp 23-27 (2018)
The article describes the basic principles of validation of the databases and laboratory information management systems used by pharmaceutical organizations. The principles are arranged on the basis of international OMCL network requirements and ISO
Externí odkaz:
https://doaj.org/article/e6a9239aed2b48f99804636b2da18d94
Autor:
K. A. Koshechkin
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 7, Iss 1, Pp 64-68 (2018)
Medicinal products evaluation is quite impossible without automation systems. In order to develop and update a large number of information systems, it is necessary either to have considerable resources, or to apply the methodology of adaptive managem
Externí odkaz:
https://doaj.org/article/6205f8d1f66f478fb5a86f000ef78eee
Autor:
K. A. Koshechkin, E. M. Rychikhina
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 7, Iss 2, Pp 122-125 (2018)
The article analyses international experience of information technology use in pharmaceutical data management. It investigates the possibility of using CALS/PLM-technologies for IT-based management of pharmacy-related activities as exemplified by the
Externí odkaz:
https://doaj.org/article/754b9da098194693872d016b0f3f645c