Zobrazeno 1 - 10
of 66
pro vyhledávání: '"K A Duggan"'
Publikováno v:
European journal of pharmacology. 873
Dialysis requiring renal failure is a silent epidemic. Despite an annual mortality of 24% the dialysis population has increased by 1-4% per annum. Regardless of the initial injury, tubulointerstitial fibrosis is a feature of the renal pathology and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefaefbb7783acd47988f85cba5ecd96
https://pubmed.ncbi.nlm.nih.gov/32014488
https://pubmed.ncbi.nlm.nih.gov/32014488
Publikováno v:
European journal of pharmacology. 862
Congestive cardiac failure has become one of the major health challenges of the 21st century and new therapies are needed to address this problem. The concentration of vasoactive intestinal peptide (VIP) in the heart has been shown to decrease as fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421a177abe81f762368490d0d0562308
https://pubmed.ncbi.nlm.nih.gov/31449808
https://pubmed.ncbi.nlm.nih.gov/31449808
Autor:
K. A. Duggan, Stephen D. Schibeci, Ornella Tolhurst, George Hodge, Ulla Simanainen, Francia Garces Suarez, Tegan Hunter, Edward Hendriks, Nicky Boulter, David J. Handelsman, Trevor Sunderland
Publikováno v:
BMC Biotechnology
Background Research into gene expression enables scientists to decipher the complex regulatory networks that control fundamental biological processes. Quantitative real-time PCR (qPCR) is a powerful and ubiquitous method for interrogation of gene exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e0988823fd584417eeac0cc25cac15
https://doi.org/10.1186/s12896-016-0256-y
https://doi.org/10.1186/s12896-016-0256-y
Autor:
M. Lowy, Leslie Schrieber, K. A. Duggan, A. Dilley, Alex Wodak, Adrian Mindel, Robin J. Willcourt, Brian J. Morris, David A. Cooper
Publikováno v:
Internal Medicine Journal. 42:822-828
Infantmalecircumcision(MC)isanimportantissueguidedbyRoyalAustralasianCollege of Physicians (RACP) policy. Here we analytically review the RACP’s 2010 policy statement ‘Circumcision of infant males’. Comprehensive evaluation in the context of pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3cde32d9576da1027246332349e0a4d
https://doi.org/10.1111/j.1445-5994.2012.02823.x
https://doi.org/10.1111/j.1445-5994.2012.02823.x
Autor:
V. Z. C. Ye, K. A. Duggan
Publikováno v:
Annals of the New York Academy of Sciences. 805:713-716
In patients with congestive cardiac failure, treatment with ACE inhibitors results in peripheral vasodilatation and an increase in cardiac output without an increase in heart rate, which suggests a positive inotropic effect. This cannot be explained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dc4d724bfd616a6b63f22c33e2a5db
https://doi.org/10.1111/j.1749-6632.1996.tb17546.x
https://doi.org/10.1111/j.1749-6632.1996.tb17546.x
Publikováno v:
Acta Physiologica Scandinavica. 179:353-360
Aims: In both normotensive and hypertensive rats, the degree of myocardial fibrosis is inversely correlated with the concentration of vasoactive intestinal peptide (VIP) in the myocardium. Treatment with nitric oxide (NO) synthase inhibitors also cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::984f2aaf22fe586ce908bf9a2b8e11f3
https://doi.org/10.1046/j.0001-6772.2003.01200.x
https://doi.org/10.1046/j.0001-6772.2003.01200.x
Early Myocardial Fibrosis is Associated with Depletion of Vasoactive Intestinal Peptide in Rat Heart
Publikováno v:
Experimental Physiology. 87:539-546
In this study we sought to determine whether early myocardial fibrosis is associated with depletion of vasoactive intestinal peptide (VIP) in the heart, thereby suggesting a possible pathogenetic role for depletion of myocardial VIP levels in the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e4130a7649e1abc1f99c8f07637e91
https://doi.org/10.1113/eph8702335
https://doi.org/10.1113/eph8702335
Publikováno v:
Acta Physiologica Scandinavica. 174:209-215
(1) Salt sensitive hypertension, which occurs as a result of treatment with nitric oxide synthase inhibitors, is associated with a loss of the usual down-regulatory effect of dietary sodium on angiotensin II (Ang II) synthesis. In the spontaneous hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08fff8c257bb87825d45b6c4b5689211
https://doi.org/10.1046/j.1365-201x.2002.00937.x
https://doi.org/10.1046/j.1365-201x.2002.00937.x
Publikováno v:
Experimental Physiology. 87:1-8
In the Dahl salt-sensitive hypertensive rat, a diet containing L-arginine, the natural substrate for nitric oxide synthase, abrogates the hypertension. We postulated that nitric oxide synthase inhibition might induce a salt-sensitive form of hyperten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ad69fdf8d2309e33e30f61595855a6
https://doi.org/10.1113/eph8702322
https://doi.org/10.1113/eph8702322
Autor:
V. Z. C. Ye, K. A. Duggan
Publikováno v:
Acta Physiologica Scandinavica. 169:21-27
Changes in angiotensin-converting enzyme (ACE) activity appear to be important in mediating the natriuresis which ensues after administration of an oral or gastric sodium load. In this study, we sought to determine the time course of the changes in A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f639d385f089fe919fc6cbcf8c03066c
https://doi.org/10.1046/j.1365-201x.2000.00720.x
https://doi.org/10.1046/j.1365-201x.2000.00720.x