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Interactions between lac repressor protein and site-specific bromodeoxyuridine-substituted operator DNA. Ultraviolet footprinting and protein-DNA cross-link formation

Autor: K L Wick, Kathleen S. Matthews

Publikováno v: Journal of Biological Chemistry. 266:6106-6112

Specific contacts between the lac repressor and operator have been explored using 5-bromodeoxyuridine-substituted DNA. Substitution of BrdU for single thymidine positions in a synthetic 40-base pair operator provides substrate for ultraviolet irradia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b6b6a366983299dfb08781c0af95ffb
https://doi.org/10.1016/s0021-9258(18)38090-6

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Decentralized didactic training for physician assistants: academic performances across training sites

Autor: R, Ballweg, K H, Wick

Publikováno v: Journal of allied health. 28(4)

Decentralized training for the didactic portion of allied health programs has been assessed for its ability to increase the likelihood that graduates will practice in underserved areas. The question still remains whether these distant sites provide a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7afe9bac784a7720d902010ae56cc989
https://pubmed.ncbi.nlm.nih.gov/10614554

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Interactions between lac repressor protein and site-specific bromodeoxyuridine-substituted operator DNA. Ultraviolet footprinting and protein-DNA cross-link formation

Autor: K L, Wick, K S, Matthews

Publikováno v: The Journal of biological chemistry. 266(10)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::340ac8758794ea26c24d7b2b47598042
https://pubmed.ncbi.nlm.nih.gov/2007568

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Identification of amino acids in lac repressor protein cross-linked to operator DNA specifically substituted with bromodeoxyuridine

Autor: T D, Allen, K L, Wick, K S, Matthews

Publikováno v: The Journal of biological chemistry. 266(10)

Amino acids in lac repressor protein which form cross-links to lac operator DNA specifically substituted with bromodeoxyuridine (BrdU) have been identified. Five sites of cross-linking in BrdU-substituted operator DNA were found at positions +3, +4,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::feb786fa0b9b62c622c5ff31f01f7531
https://pubmed.ncbi.nlm.nih.gov/2007569

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Adhesion-to-skin performance of a new transdermal nitroglycerin adhesive patch

Autor: K A, Wick, S M, Wick, R W, Hawkinson, J L, Holtzman

Publikováno v: Clinical therapeutics. 11(3)

Six men and six women participated in a study designed to compare adhesion-to-skin measurements of three transdermal nitroglycerin patch formulations (Minitran, Transderm-Nitro 5, and Nitro-Dur II) with an occlusive surgical tape control. After 24 ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c4b5c9c34a05773466e14a57ac1d4d73
https://pubmed.ncbi.nlm.nih.gov/2501033

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Performance of a new transdermal nitroglycerin adhesive patch formulation

Autor: D J, Riedel, K A, Wick, R W, Hawkinson, C A, Kolars, J K, Crowley, K E, Armstrong, S F, Chang, L I, Harrison, S R, de Dennis

Publikováno v: Clinical therapeutics. 11(2)

This two-period crossover study in 24 healthy men compared the transdermal absorption of nitroglycerin from a new 20-cm2 nitroglycerin adhesive transdermal patch applied for a single 24-hour period (q24hr) with that from one inch of 2% nitroglycerin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b6415209c5c961167a8b5ded7e7f0e7d
https://pubmed.ncbi.nlm.nih.gov/2500248

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Drug release rates from four sizes of a new transdermal nitroglycerin adhesive patch

Autor: D J, Riedel, K A, Wick, R W, Hawkinson, C A, Kolars, J K, Crowley, L I, Harrison, S R, de Dennis

Publikováno v: Clinical therapeutics. 11(3)

This study was conducted to determine the amount of nitroglycerin released from transdermal nitroglycerin patches of four different sizes: 3.3 cm2, 6.7 cm2, 13.3 cm2, and 20 cm2. Thirty healthy men received a single 24-hour application of each patch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d023e939c9e6ce1db295b7ff52754cd6
https://pubmed.ncbi.nlm.nih.gov/2501032

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