Výsledky vyhledávání - "K A, Steinmetz"

Salmeterol/fluticasone propionate (50500 μg) in combination in a Diskus® inhaler (Seretide®) is effective and safe in the treatment of steroid-dependent asthma

Autor: W. R. Pieters, K.-O. Steinmetz, N. J. J. Schlösser, M. Aubier

Publikováno v: Respiratory Medicine. 93(12):876-884

This multicentre double-blind, double-dummy study compared the safety and efficacy of a new combination Diskus inhaler containing both salmeterol 50 microg and fluticasone propionate 500 microg (Seretide, GlaxoWellcome, France) with the same doses of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fe18f1d93b720b340a71512b6877c0

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Hypomethylation of the rat glutathione S-transferase pi (GSTP) promoter region isolated from methyl-deficient livers and GSTP-positive liver neoplasms

Autor: I P Pogribny, K L Steinmetz, Henry C. Pitot, S J James

Publikováno v: Carcinogenesis. 19:1487-1494

DNA methylation at the 5-position on the cytosine ring in CpG dinucleotides (CpG sites) appears to play an important role in regulating gene expression. In general, there is an inverse relationship between promoter CpG site methylation and the potent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117f8309161007101c9ce14471a520ac
https://doi.org/10.1093/carcin/19.8.1487

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Evaluation of unscheduled DNA synthesis (UDS) and replicative DNA synthesis (RDS) following treatment of rats and mice with p-dichlorobenzene

Autor: J H, Sherman, R S, Nair, K L, Steinmetz, J C, Mirsalis, E R, Nestmann, J A, Barter

Publikováno v: Teratogenesis, carcinogenesis, and mutagenesis. 18(6)

p-Dichlorobenzene (PDCB) has been reported to produce tumors in the male and female mouse liver and in the male rat kidney in 2-year gavage studies (NPT, 1987). To elucidate the possible mechanisms of carcinogenicity more fully, UDS and RDS were eval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e59371c35bfa01c6ac657a3a0223d22
https://pubmed.ncbi.nlm.nih.gov/10052566

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Vegetables, fruit, and cancer prevention: a review

Autor: K A, Steinmetz, J D, Potter

Publikováno v: Journal of the American Dietetic Association. 96(10)

In this review of the scientific literature on the relationship between vegetable and fruit consumption and risk of cancer, results from 206 human epidemiologic studies and 22 animal studies are summarized. The evidence for a protective effect of gre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d74b781f6f87cd2cfc555e9da62ac629
https://pubmed.ncbi.nlm.nih.gov/8841165

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Reduced risk of colon cancer with high intake of vitamin E: the Iowa Women's Health Study

Autor: R M, Bostick, J D, Potter, D R, McKenzie, T A, Sellers, L H, Kushi, K A, Steinmetz, A R, Folsom

Publikováno v: Cancer research. 53(18)

Antioxidant micronutrients, including vitamin E, vitamin C, the carotenoids, and selenium, defend the body against free radicals and reactive oxygen molecules, suggesting a potential for these dietary components in cancer prevention. To investigate w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ffeab95de68300f8adad715330791907
https://pubmed.ncbi.nlm.nih.gov/8364919

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Vegetables, fruit, and lung cancer in the Iowa Women's Health Study

Autor: K A, Steinmetz, J D, Potter, A R, Folsom

Publikováno v: Cancer research. 53(3)

Previous epidemiological studies have shown an inverse association between vegetable and fruit consumption and lung cancer risk; few of these studies have been prospective or have focused upon women. In 1986, we assessed food intake in 41,837 Iowa wo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76f9b650c4a14755585f0285c8f32828
https://pubmed.ncbi.nlm.nih.gov/8425185

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