Zobrazeno 1 - 10
of 202
pro vyhledávání: '"K A, Pearce"'
Autor:
G. Veggiani, R. Villaseñor, G. D. Martyn, J. Q. Tang, W. M. Krone, J. Gu, C. Chen, M. L. Waters, K. H. Pearce, T. Baubec, S. S. Sidhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Engineered chromodomains are promising probes to analyze histone methylation. Here the authors designed high-affinity chromodomains for enhanced genome-wide binding analysis, live-cell imaging and ultra-potent CRISPR-based gene repression.
Externí odkaz:
https://doaj.org/article/c874d75ba0bf4500b8d0f94e68765f16
Autor:
Shannon M. MacKenzie, Alexandra Pontefract, R. Terik Daly, Jacob J. Buffo, Gordon R. Osinski, Christopher J. Cline II, Mark J. Cintala, Kathleen L. Craft, Mallory J. Kinczyk, Joshua Hedgepeth, Sarah M. Hörst, Abel Méndez, Ben K. D. Pearce, Angela M. Stickle, Steven D. Vance
Publikováno v:
The Planetary Science Journal, Vol 5, Iss 8, p 176 (2024)
Evidence for the beneficial role of impacts in the creation of urable or habitable environments on Earth prompts the question of whether meteorite impacts could play a similar role at other potentially urable/habitable worlds like Enceladus, Europa,
Externí odkaz:
https://doaj.org/article/f9fd7c9d4c384a0b92f2970d944677b6
Autor:
Ben K. D. Pearce, Sarah M. Hörst, Christopher J. Cline, Mark J. Cintala, Chao He, Joshua A. Sebree, Shannon M. MacKenzie, R. Terik Daly, Alexandra J. Pontefract, Cara Pesciotta
Publikováno v:
The Planetary Science Journal, Vol 5, Iss 3, p 68 (2024)
Impacts are critical to producing the aqueous environments necessary to stimulate prebiotic chemistry on Titan’s surface. Furthermore, organic hazes resting on the surface are a likely feedstock of biomolecules. In this work, we conduct impact expe
Externí odkaz:
https://doaj.org/article/63ad791098954d2298c6b6a34d5eeab7
Publikováno v:
The Planetary Science Journal, Vol 5, Iss 1, p 23 (2024)
Over 4 billion years ago, Earth is thought to have been a hazy world akin to Saturn’s moon Titan. The organic hazes in the atmosphere at this time could have contained a vast inventory of life’s building blocks and thus may have seeded warm littl
Externí odkaz:
https://doaj.org/article/48a11a660c4d4ce38e0423f140e404ce
Autor:
Klaus Paschek, Dmitry A. Semenov, Ben K. D. Pearce, Kevin Lange, Thomas K. Henning, Ralph E. Pudritz
Publikováno v:
The Astrophysical Journal, Vol 942, Iss 1, p 50 (2023)
Prebiotic molecules, fundamental building blocks for the origin of life, have been found in carbonaceous chondrites. The exogenous delivery of these organic molecules onto the Hadean Earth could have sparked the polymerization of the first RNA molecu
Externí odkaz:
https://doaj.org/article/6af031156ad24f3abddc5c944b995419
Autor:
G. Veggiani, R. Villaseñor, G. D. Martyn, J. Q. Tang, M. W. Krone, J. Gu, C. Chen, M. L. Waters, K. H. Pearce, T. Baubec, S. S. Sidhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/16dbff1044e14403a67465eb69dd73f3
Autor:
Alan King Lun Liu, Tsz Wing Chau, Ernest Junwei Lim, Idil Ahmed, Raymond Chuen-Chung Chang, Michail E. Kalaitzakis, Manuel B. Graeber, Steve M. Gentleman, Ronald K. B. Pearce
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Although the precise neuropathological substrates of cognitive decline in Parkinson’s disease (PD) remain elusive, it has long been regarded that pathology in the CA2 hippocampal subfield is characteristic of Lewy body dementias, including
Externí odkaz:
https://doaj.org/article/4ce6a7e6434942cdb4b4deb6fbdf4987
Autor:
Klaus Paschek, Kai Kohler, Ben K. D. Pearce, Kevin Lange, Thomas K. Henning, Oliver Trapp, Ralph E. Pudritz, Dmitry A. Semenov
Publikováno v:
Life, Vol 12, Iss 3, p 404 (2022)
The origin of life might be sparked by the polymerization of the first RNA molecules in Darwinian ponds during wet-dry cycles. The key life-building block ribose was found in carbonaceous chondrites. Its exogenous delivery onto the Hadean Earth could
Externí odkaz:
https://doaj.org/article/d6d79a8d593548ab92bcbeba51574a1d
A critical early stage for the origin of life on Earth may have involved the production of hydrogen cyanide (HCN) in a reducing, predominantly H$_2$ atmosphere. HCN is crucial for the origin of life as it is a possible precursor to several biomolecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319b627fd25ed10a24c7fd6bc081a5ed
http://arxiv.org/abs/2209.09257
http://arxiv.org/abs/2209.09257
Towards RNA life on Early Earth: From atmospheric HCN to biomolecule production in warm little ponds
Autor:
Ben K. D. Pearce, Karan Molaverdikhani, Ralph E. Pudritz, Thomas Henning, Kaitlin E. Cerrillo
The origin of life on Earth involves the early appearance of an information-containing molecule such as RNA. The basic building blocks of RNA could have been delivered by carbon-rich meteorites, or produced in situ by processes beginning with the syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfff2de0137652df1db231dcf2a4e961
https://doi.org/10.5194/egusphere-egu22-1778
https://doi.org/10.5194/egusphere-egu22-1778