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Autor:
R V, Chari, K A, Jackel, L A, Bourret, S M, Derr, B M, Tadayoni, K M, Mattocks, S A, Shah, C, Liu, W A, Blättler, V S, Goldmacher
Publikováno v:
Cancer research. 55(18)
Bis-indolyl-(seco)-1,2,9a-tetrahydrocyclopropa[c]benz[e]indol-4-on e compounds are synthetic analogues of CC-1065 that are highly cytotoxic toward a broad spectrum of tumor cell lines. One of these compounds, called DC1, was conjugated to antibodies