Zobrazeno 1 - 10
of 356
pro vyhledávání: '"K A, Grant"'
Autor:
K. E. Grant, M. N. Repasch, K. M. Finstad, J. D. Kerr, M. Marple, C. J. Larson, T. A. B. Broek, J. Pett-Ridge, K. J. McFarlane
Publikováno v:
Biogeosciences, Vol 21, Pp 4395-4411 (2024)
Soil organic carbon (SOC) is a large, dynamic reservoir composed of a complex mixture of plant- and microbe-derived compounds with a wide distribution of cycling timescales and mechanisms. The distinct residence times of individual carbon components
Externí odkaz:
https://doaj.org/article/25941bb7219247d0bb352678536e853c
Autor:
R. Hennekam, K. M. Grant, E. J. Rohling, R. Tjallingii, D. Heslop, A. P. Roberts, L. J. Lourens, G.-J. Reichart
Publikováno v:
Climate of the Past, Vol 18, Pp 2509-2521 (2022)
In eastern Mediterranean sediments, the titanium-to-aluminum ratio (Ti/Al) captures relative variability in eolian to river-derived material and predominantly integrates climate signals over the Saharan and Sahel regions. Long Ti/Al time series can,
Externí odkaz:
https://doaj.org/article/da01983608f9401aaa61a662aed232fc
Autor:
Ibrahim Y. Abdelgawad, Kevin Agostinucci, Bushra Sadaf, Marianne K. O. Grant, Beshay N. Zordoky
Publikováno v:
Frontiers in Aging, Vol 4 (2023)
Introduction: Doxorubicin (DOX), a chemotherapeutic drug, induces senescence and increases the secretion of senescence-associated secretory phenotype (SASP) in endothelial cells (ECs), which contributes to DOX-induced inflammaging. Metformin, an anti
Externí odkaz:
https://doaj.org/article/3e9bb987275342a98f7502970525dca0
Autor:
Marianne K. O. Grant, Maria Razzoli, Ibrahim Y. Abdelgawad, Rachel Mansk, Davis Seelig, Alessandro Bartolomucci, Beshay N. Zordoky
Publikováno v:
Stress, Vol 25, Iss 1, Pp 291-304 (2022)
Childhood cancer survivors have a high risk for premature cardiovascular diseases, mainly due to cardiotoxic cancer treatments such as doxorubicin (DOX). Psychosocial stress is a significant cardiovascular risk factor and an enormous burden in childh
Externí odkaz:
https://doaj.org/article/937f9516f6584ce1aeb6dbce0b53c2c6
Autor:
Joyce Nankumbi, Frederick K. E. Grant, Lindiwe Sibeko, Evelyn Mercado, Norman Kwikiriza, Simon Heck, Lorraine S. Cordeiro
Publikováno v:
Frontiers in Public Health, Vol 10 (2023)
ObjectiveVitamin A deficiency (VAD) has serious public health consequences including morbidity and mortality for populations in low and middle-income countries (LMICs), especially for children under 5 years and pregnant women. LMICs are at greater ri
Externí odkaz:
https://doaj.org/article/49922fc5609e466b8d2f111fd89c47de
Autor:
L. Rodríguez-Sanz, S. M. Bernasconi, G. Marino, D. Heslop, I. A. Müller, A. Fernandez, K. M. Grant, E. J. Rohling
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/74852605501c480ab4766f6600f4b81a
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 391 (2023)
Sex is a salient risk factor in the development of doxorubicin-induced cardiotoxicity. Sex differences in the heart’s ability to respond to hypertrophic stimuli in doxorubicin-exposed animals have not been reported. We identified the sexual dimorph
Externí odkaz:
https://doaj.org/article/4832b962dfa9451ebb9c6a1abf8d36cd
Autor:
Kevin Agostinucci, Marianne K. O. Grant, Davis Seelig, Doğacan Yücel, Jop van Berlo, Alessandro Bartolomucci, Jason R. B. Dyck, Beshay N. Zordoky
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Hypertension is the most significant risk factor for heart failure in doxorubicin (DOX)-treated childhood cancer survivors. We previously developed a two-hit mouse model of juvenile DOX-induced latent cardiotoxicity that is exacerbated by adult-onset
Externí odkaz:
https://doaj.org/article/0898dfc3d92b49c9936772f98678f466
Autor:
M. R. Lee, T. A. Shnitko, S. W. Blue, A. V. Kaucher, A. J. Winchell, D. W. Erikson, K. A. Grant, L. Leggio
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The location and extent of intranasal oxytocin brain penetrance has not been shown. Here the authors show that oxytocin, administered intranasally, enters brain regions along the trajectories of the olfactory and trigeminal nerves and there, reaches
Externí odkaz:
https://doaj.org/article/d3867b18524849f3b187518df818521b
Autor:
Ibrahim Y. Abdelgawad, Kevin Agostinucci, Somia G. Ismail, Marianne K. O. Grant, Beshay N. Zordoky
Publikováno v:
Cells, Vol 11, Iss 13, p 1992 (2022)
Doxorubicin (DOX) induces endothelial cell (EC) senescence, which contributes to endothelial dysfunction and cardiovascular complications. Senolytic drugs selectively eliminate senescent cells to ameliorate senescence-mediated pathologies. Previous s
Externí odkaz:
https://doaj.org/article/8c9b283b40fb4b2a85518d987dde1ea5