Zobrazeno 1 - 10
of 21
pro vyhledávání: '"K A, Eidne"'
Publikováno v:
Pharmaceutical News. 9:317-325
Publikováno v:
Endocrinology. 136:172-179
Rat GnRH pituitary receptor complementary DNA was used to isolate a truncated clone from a rat corpus luteum complementary DNA library that proved to be identical in sequence to the rat anterior pituitary GnRH receptor. The distribution of the GnRH r
Publikováno v:
Journal of Biological Chemistry. 269:19933-19940
A cDNA encoding the long isoform of the rat thyrotropin releasing hormone (TRH) receptor was expressed stably in HEK-293 cells. Polymerase chain reaction analysis confirmed expression of mRNA encoding only the long and not the short isoform. Activati
Publikováno v:
The Journal of biological chemistry. 276(16)
The ability of G-protein-coupled receptors (GPCRs) to interact to form new functional structures, either forming oligomers with themselves or forming associations with other intracellular proteins, has important implications for the regulation of cel
Autor:
J V, Cook, K A, Eidne
Publikováno v:
Endocrinology. 138(7)
In this study, site-directed mutagenesis and biochemical strategies have been used to establish whether disulfide bonding between extracellular Cys residues contributes to the structural integrity of the GnRH receptor (GnRH-R) and, if so, to delineat
Autor:
R, Collu, J, Tang, J, Castagné, G, Lagacé, N, Masson, C, Huot, C, Deal, E, Delvin, E, Faccenda, K A, Eidne, G, Van Vliet
Publikováno v:
The Journal of clinical endocrinology and metabolism. 82(5)
Isolated central hypothyroidism, characterized by insufficient TSH secretion resulting in low levels of thyroid hormones, is a rare disorder. We report a boy in whom isolated central hypothyroidism was diagnosed at 9 yr of age. Complete absence of TS
Publikováno v:
The Journal of endocrinology. 149(3)
In rat ovarian granulosa cells the effects of GnRH are determined by the state of granulosa cell development with mainly inhibitory actions in immature cells and stimulatory actions in differentiated mature cells. These developmentally related effect
Publikováno v:
Cancer research. 56(9)
The presence of a direct extra-pituitary action of gonadotropin-releasing hormone (GnRH) via specific receptors in endometrial cancer (EC) has been suggested as an explanation for the therapeutic effect of GnRH analogue (GnRHa) in recurrent disease.
Publikováno v:
Molecular pharmacology. 49(4)
Human embryonic kidney 293 cells that had been transfected to express the long isoform of the rat thyrotropin-releasing hormone (TRH) receptor (clone E2) were further transfected with a cDNA encoding the murine version of G11alpha. A clone was isolat
Publikováno v:
The Journal of biological chemistry. 269(31)
A cDNA encoding the long isoform of the rat thyrotropin releasing hormone (TRH) receptor was expressed stably in HEK-293 cells. Polymerase chain reaction analysis confirmed expression of mRNA encoding only the long and not the short isoform. Activati