Zobrazeno 1 - 10
of 40
pro vyhledávání: '"K A, Chester"'
Autor:
K. G. Chester, B. L. Massoudi
Publikováno v:
Yearbook of Medical Informatics. 26:241-247
Summary Objectives: To survey advances in public and population health and epidemiology informatics over the past 18 months. Methods: We conducted a review of English-language research works conducted in the domain of public and population health inf
Autor:
K S, CHESTER
Publikováno v:
The Scientific monthly. 61
Autor:
K S, CHESTER
Publikováno v:
Control de plagas. 9(1)
Autor:
K. A. Chester, R. H. J. Begent
Publikováno v:
Biochemical Society Transactions. 25:715-717
Autor:
A, Huhalov, K A, Chester
Publikováno v:
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 48(4)
An ideal molecule to deliver radioimmunotherapy (RIT) would be target specific and have prolonged residence time at high concentrations in the tumour with rapid clearance from normal tissues. It would also be non-immunogenic. These features can be ra
Publikováno v:
Cancer research. 61(9)
Vascular endothelial growth factor (VEGF) is produced by cancer cells in response to hypoxia and is the primary stimulant of vascularization in solid tumors. Endothelial cells lining the blood vessels of these tumors have a high concentration of rece
Autor:
A, Mayer, E, Tsiompanou, D, O'Malley, G M, Boxer, J, Bhatia, A A, Flynn, K A, Chester, B R, Davidson, A A, Lewis, M C, Winslet, A P, Dhillon, A J, Hilson, R H, Begent
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(5)
In radioimmunoguided surgery (RIGS), a radiolabeled antibody is given i.v. before surgery and a hand-held gamma-detecting probe is used to locate tumor in the operative field. The rapid blood clearance and good tumor penetration of single-chain Fv an
Autor:
J, Bhatia, S K, Sharma, K A, Chester, R B, Pedley, R W, Boden, D A, Read, G M, Boxer, N P, Michael, R H, Begent
Publikováno v:
International journal of cancer. 85(4)
Antibody-directed enzyme prodrug therapy (ADEPT) targets an enzyme selectively to a tumor where it converts a relatively non-toxic prodrug to a potent cytotoxic drug. Previous clinical work using antibody-enzyme chemical conjugates has been limited b
Publikováno v:
Human gene therapy. 9(2)
Cancer-specific antigens are promising targets for the specific delivery of certain drugs or genes to cancer cells in cancer therapy. Carcinoembryonic antigen (CEA) is one of the cancer-associated antigens predominantly detected in the gastrointestin
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(1)
We describe the engineering of a novel single-chain fragment (scFv) metallothionein (MET) containing anti-carcinoembryonic antigen (CEA) antibody (referred to as MET-scFv) for use as a diagnostic imaging agent in colorectal cancer.Site-directed cloni