Zobrazeno 1 - 10
of 14
pro vyhledávání: '"K A, Brune"'
Autor:
H. T. Heidemann, K. H. Brune
Publikováno v:
Mycoses. 34:401-404
Summary. Fluey tosine (5-fluorocytosine), a potent antimycotic drug against various systemic infections such as candidosis, aspergillosis and cryptococcosis, is extensively excreted by the kidneys, yet its possible role in renal function is not known
Autor:
G P Dubé, Mais De, W L Kurtz, Joseph A. Jakubowski, K A Brune, Barbara G. Utterback, F. Mohamadi, M. M. Spees
Publikováno v:
ChemInform. 23
A number of phenylsulfonamido derivatives have been synthesized and tested for their ability to inhibit: a) thromboxane A 2 /prostaglandin H 2 ( TXA 2 PGH 2 ) mimetic (U46619)- induced guinea pig platelet aggregation; b) aortic ring contraction; and
Publikováno v:
Volume 7: Turbomachinery, Parts A and B.
One solution for reducing the nitrogen oxide emissions of diesel engines is the Low-Pressure-Exhaust-Gas-Recirculation method. This solution involves gathering exhaust gas from behind the turbine and mixing it with the aspirated fresh air upstream of
Autor:
G P Dubé, Joseph A. Jakubowski, M. M. Spees, K A Brune, W L Kurtz, Mais De, F. Mohamadi, Barbara G. Utterback
Publikováno v:
European Journal of Medicinal Chemistry. 26:821-827
A number of phenylsulfonamido derivatives have been synthesized and tested for their ability to inhibit: a) thromboxane A 2 /prostaglandin H 2 ( TXA 2 PGH 2 ) mimetic (U46619)- induced guinea pig platelet aggregation; b) aortic ring contraction; and
Publikováno v:
Cancer journal (Sudbury, Mass.). 7(4)
Pancreatic cancer is the fourth leading cause of cancer death in both men and women in the United States and will be responsible for an estimated 28,900 deaths in 2001. Relatively little is known of its etiology, and the only well-established risk fa
Autor:
A C, Tersmette, G M, Petersen, G J, Offerhaus, F C, Falatko, K A, Brune, M, Goggins, E, Rozenblum, R E, Wilentz, C J, Yeo, J L, Cameron, S E, Kern, R H, Hruban
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(3)
It has been estimated that familial aggregation and genetic susceptibility play a role in as many as 10% of patients with pancreatic cancer (PC). The quantified prospective risk of PC among first-degree relatives of PC patients has not been investiga
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(2)
A novel thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor ligand, (+)5(Z)-7-[3-endo-phenylsulfonylamino[2.2.1]-bicyclohept-2-e xo- yl]-heptenoic acid [(+)-S-145], was evaluated in guinea pigs to assess the in vivo pharmacodynamic profile of this c
Autor:
G P, Dubé, D E, Mais, J A, Jakubowski, K A, Brune, B G, Utterback, T A, True, L E, Rinkema, W L, Kurtz
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(2)
The stereoisomers of S-145, a novel thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor ligand, were compared to TXA2/PGH2 receptor antagonists, SQ29548 and BM13505 in guinea pig platelets, aortas and trachea. Equilibrium binding assays in platelets
Autor:
H T, Heidemann, K H, Brune
Publikováno v:
Mycoses. 34(9-10)
Flucytosine (5-fluorocytosine), a potent antimycotic drug against various systemic infections such as candidosis, aspergillosis and cryptococcosis, is extensively excreted by the kidneys, yet its possible role in renal function is not known. In the p
Publikováno v:
Molecular pharmacology. 39(1)
Thromboxane A2 (TXA2) and prostaglandin H2 (PGH2) are potent constrictors of airway smooth muscle and may mediate some of the pulmonary effects of leukotrienes. To date, the TXA2/PGH2 receptor in lung has not been well characterized. In this report,