Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Külliki Varvas"'
Autor:
Nigulas Samel, Külliki Varvas, Karin Valmsen, Helike Lõhelaid, Kristella Hansen, Reet Järving, Ivar Järving, Reet Kurg
Publikováno v:
Insect Biochemistry and Molecular Biology. 39:851-860
Prostaglandins, well-known lipid mediators in vertebrate animals, have also shown to play certain regulatory roles in insects and other arthropods acting on reproduction, immune system and ion transport. However, knowledge of their biosynthetic pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993702f2fbeb87a3598e1125402b978d
https://doi.org/10.1016/j.ibmb.2009.10.002
https://doi.org/10.1016/j.ibmb.2009.10.002
Autor:
Helike Lõhelaid, Ivar Järving, Karin Valmsen, Külliki Varvas, Reet Järving, Nigulas Samel, Malle Kreen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1780:315-321
The conversion of fatty acid hydroperoxides to allene epoxides is catalysed by a cytochrome P450 in plants. In contrast, in the coral Plexaura homomalla, a catalase-related hemoprotein fused to the lipoxygenase (LOX) was found to function as an allen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34f88fab23b54d8ed9103e8e648aaa4
https://doi.org/10.1016/j.bbagen.2007.10.010
https://doi.org/10.1016/j.bbagen.2007.10.010
Autor:
Nigulas Samel, Külliki Varvas, Claus Schneider, Alan R. Brash, William E. Boeglin, Ivar Järving, Karin Valmsen
Publikováno v:
European Journal of Biochemistry. 271:3533-3538
It has been known for 30 years that the gorgonian coral Plexaura homomalla contains either 15S- or 15R-configuration prostaglandins (PGs), depending on its location in the Caribbean. Recently we showed that the 15R-PGs in the R-variety of P. homomall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ff197f4be55083aae6b1e0b4c9f412d
https://doi.org/10.1111/j.0014-2956.2004.04289.x
https://doi.org/10.1111/j.0014-2956.2004.04289.x
Publikováno v:
Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology. 174
Prostaglandins (PG) have been shown to play important physiological roles in insects and marine invertebrates, yet the knowledge of their biosynthetic pathways is often lacking. Recently, we described cyclooxygenases in two amphipod crustaceans, Gamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb0fcccf16b7aec3c5b47da4b9d9cee
https://pubmed.ncbi.nlm.nih.gov/24947207
https://pubmed.ncbi.nlm.nih.gov/24947207
Autor:
William E. Boeglin, Alan R. Brash, Nigulas Samel, Karin Valmsen, Tõnis Pehk, Külliki Varvas, Ivar Järving, Reet Koljak
Publikováno v:
Proceedings of the National Academy of Sciences. 98:7700-7705
The highest concentrations of prostaglandins in nature are found in the Caribbean gorgonian Plexaura homomalla . Depending on its geographical location, this coral contains prostaglandins with typical mammalian stereochemistry (15 S -hydroxy) or the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d61cba4adfe21e8ef06adf8da9b7ea1
https://doi.org/10.1073/pnas.131022398
https://doi.org/10.1073/pnas.131022398
Autor:
Nigulas Samel, Alan R. Brash, Külliki Varvas, Reet Koljak, Mart Ustav, Ivar Järving, William E. Boeglin, Reet Kurg, Karin Valmsen
Publikováno v:
Journal of Biological Chemistry. 276:7033-7040
In vertebrates, the synthesis of prostaglandin hormones is catalyzed by cyclooxygenase (COX)-1, a constitutively expressed enzyme with physiological functions, and COX-2, induced in inflammation and cancer. Prostaglandins have been detected in high c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03fc572480b0dea0f9f4e78273c49786
https://doi.org/10.1074/jbc.m009803200
https://doi.org/10.1074/jbc.m009803200
Publikováno v:
Journal of Biological Chemistry. 274:9923-9929
Certain corals are rich natural sources of prostaglandins, the metabolic origin of which has remained undefined. By analogy with the lipoxygenase/allene oxide synthase pathway to jasmonic acid in plants, the presence of (8R)-lipoxygenase and allene o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::851ebe52bbcf59fe737816817b85f456
https://doi.org/10.1074/jbc.274.15.9923
https://doi.org/10.1074/jbc.274.15.9923
Autor:
Külliki Varvas, Aleksander-Mati Müürisepp, Ivar Järving, Tõnis Pehk, Annika Lopp, Nigulas Samel, Reet Koljak
Publikováno v:
Tetrahedron. 54:179-186
Six new polyoxygenated sterols 1–6 were isolated from the soft coral Gersemia fruticosa. The structures of these compounds were determined by MS. 1H- and 13C- 1D and 2D FT NMR spectroscopy. Compounds 1–6 showed a moderate cytotoxic activity again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6070046f0c1166642a5067882e64289
https://doi.org/10.1016/s0040-4020(97)10268-x
https://doi.org/10.1016/s0040-4020(97)10268-x
Publikováno v:
Tetrahedron Letters. 35:8267-8270
An acetone powder preparation of the White Sea soft coral Gersemia fruticosa converts exogenous arachidonic acid to a prostaglandin-endoperoxide, identified as PGG 2 by chemical and spectral studies. The latter serves as a key intermediate from which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d88d5a47cf67c628f8e25604227a46b2
https://doi.org/10.1016/0040-4039(94)88299-1
https://doi.org/10.1016/0040-4039(94)88299-1
Autor:
Aino Vahemets, Külliki Varvas, Ivar Järving, Tõnis Pehk, Aleksander-Mati Müürisepp, Ülo Lille, Nigulas Samel, Reet Koljak
Publikováno v:
Tetrahedron Letters. 34:3643-3646
The White Sea soft coral Gersemia fruticosa has been found to convert exogeneous arachidonic acid to optically active prostaglandins D 2 , E 2 , F 2α and 15-keto-F 2α , all of which were also isolated as endogenous constituents from the same coral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be3ffa1990f51b41e66cb3d22714491b
https://doi.org/10.1016/s0040-4039(00)73658-6
https://doi.org/10.1016/s0040-4039(00)73658-6