Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Külli Jaako"'
Autor:
Maj N. Enevoldsen, Artur Kochoyan, Monika Jurgenson, Külli Jaako, Oksana Dmytriyeva, Peter S. Walmod, Jesper D. Nielsen, Janne Nielsen, Shizhong Li, Irina Korshunova, Boris Klementiev, Tatiana Novikova, Alexander Zharkovsky, Vladimir Berezin, Elisabeth Bock
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 3, Pp 533-545 (2012)
The fibroblast growth factor receptor (FGFR) plays a vital role in the development of the nervous system regulating a multitude of cellular processes. One of the interaction partners of the FGFR is the neural cell adhesion molecule (NCAM), which is k
Externí odkaz:
https://doaj.org/article/9fcbe29b8a84470280cc234b1ecce148
Autor:
Kaili Anier, Kelli Somelar, Külli Jaako, Margret Alttoa, Kerli Sikk, Raul Kokassaar, Kai Kisand, Anti Kalda
Publikováno v:
Clinical Epigenetics. 14
Background Several reports have provided crucial evidence in animal models that epigenetic modifications, such as DNA methylation, may be involved in psychostimulant-induced stable changes at the cellular level in the brain. Epigenetic editors DNA me
Publikováno v:
Research in Social and Administrative Pharmacy. 18:e2
Autor:
Kaili Anier, Liga Zvejniece, Monika Jürgenson, Alexander Zharkovsky, Anu Aonurm-Helm, Külli Jaako, Kelli Somelar
Publikováno v:
Brain research. 1758
Chronic-pain patients often suffer from depression. In rodent models of neuropathic pain, animals develop depression-like and anxiety behaviors, indicating a relationship between chronic pain and affective disorders. However, the underlying neurobiol
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 124:40-49
Prolyl oligopeptidase (PREP) is an abundant peptidase in the brain and periphery, but its physiological functions are still largely unknown. Recent findings point to a role for PREP in inflammatory processes. This study assessed the cellular and extr
Autor:
Mait Metelitsa, Jaanus Harro, Külli Jaako, Marten Vares, Kai Tiitsaar, Cristina Kroon, Kadri Kõiv, Karita Laugus
Publikováno v:
Journal of psychopharmacology (Oxford, England). 33(12)
Background:Individual vulnerability to stress manifests in the interaction of innate properties and environment. There is a growing interest in the individual variability in vulnerability to stress and how it contributes to the development of psychia
Autor:
Markus Morawski, Corinna Höfling, Alexander Zharkovsky, Antti Nurmi, Iida Peltonen, Natalia Kulesskaya, Nina Vartiainen, Vootele Voikar, Steffen Roßner, Külli Jaako, J. Arturo García-Horsman, Pekka T. Männistö
Publikováno v:
European Neuropsychopharmacology. 26:1048-1061
Prolyl oligopeptidase (PREP) has been implicated in neurodegeneration and neuroinflammation and has been considered a drug target to enhance memory in dementia. However, the true physiological role of PREP is not yet understood. In this paper, we rep
Autor:
Alexander Zharkovsky, Boris Klementiev, Maj N. Enevoldsen, Shizhong Li, Monika Jürgenson, Tatiana Novikova, Peter S. Walmod, Oksana Dmytriyeva, Artur Kochoyan, Irina Korshunova, Külli Jaako, Vladimir Berezin, Elisabeth Bock, Jesper D. Nielsen, Janne Nielsen
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 3, Pp 533-545 (2012)
Neurobiology of Disease; Vol 48
Neurobiology of Disease; Vol 48
The fibroblast growth factor receptor (FGFR) plays a vital role in the development of the nervous system regulating a multitude of cellular processes. One of the interaction partners of the FGFR is the neural cell adhesion molecule (NCAM), which is k
Autor:
Alexander Zharkovsky, Linda Klimaviciusa, Steffen Roßner, Aveli Noortoots, Keiti Parik, Markus Morawski, Kaili Anier, Anne-Marie Lambeir, Roos Van Elzen, Külli Jaako, Anu Aonurm-Helm, Alexander Waniek, Melanie Gérard
Publikováno v:
Journal of cell science
Neural cell adhesion molecule (NCAM), a membrane-associated glycoprotein and its polysialylated form (PSA-NCAM) play an important role in brain plasticity via regulating cell-cell interactions. Here, we demonstrate that the cytosolic serine protease
Publikováno v:
Pharmacological research. 113
Brain plasticity refers to the ability of the brain to undergo functionally relevant adaptations in response to external and internal stimuli. Alterations in brain plasticity have been associated with several neuropsychiatric disorders, and current t