Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kübra Kaygisiz"'
Autor:
Kübra Kaygisiz, Lena Rauch-Wirth, Arghya Dutta, Xiaoqing Yu, Yuki Nagata, Tristan Bereau, Jan Münch, Christopher V. Synatschke, Tanja Weil
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Gene therapy via retroviral vectors holds great promise for treating a variety of serious diseases. It requires the use of additives to boost infectivity. Amyloid-like peptide nanofibers (PNFs) were shown to efficiently enhance retroviral ge
Externí odkaz:
https://doaj.org/article/a0c4158a505641c896321aabc2aea5ad
Autor:
Lena Rauch-Wirth, Alexander Renner, Kübra Kaygisiz, Tatjana Weil, Laura Zimmermann, Armando A. Rodriguez-Alfonso, Desiree Schütz, Sebastian Wiese, Ludger Ständker, Tanja Weil, Dominik Schmiedel, Jan Münch
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chimeric antigen receptor (CAR)-T cell therapy is a groundbreaking immunotherapy for cancer. However, the intricate and costly manufacturing process remains a hurdle. Improving the transduction rate is a potential avenue to cut down costs and boost t
Externí odkaz:
https://doaj.org/article/c58f124f37b74c4d8faf65ee2ec09a7e
Autor:
Kübra Kaygisiz, Arghya Dutta, Lena Rauch-Wirth, Christopher V. Synatschke, Jan Münch, Tristan Bereau, Tanja Weil
Publikováno v:
Biomaterials Science
Amyloid-like nanofibers from self-assembling peptides can promote viral gene transfer for therapeutic applications. Traditionally, new sequences are discovered either from screening large libraries or by creating derivatives of known active peptides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94774d67547e73b3824753ba8080b9a7
https://hdl.handle.net/21.11116/0000-000D-6BD6-A21.11116/0000-000D-5C51-1
https://hdl.handle.net/21.11116/0000-000D-6BD6-A21.11116/0000-000D-5C51-1
Autor:
Lia-Raluca Olari, Richard Bauer, Marta Gil Miró, Verena Vogel, Laura Cortez Rayas, Rüdiger Groß, Andrea Gilg, Raphael Klevesath, Armando A. Rodríguez Alfonso, Kübra Kaygisiz, Ulrich Rupp, Pradeep Pant, Joel Mieres-Pérez, Lena Steppe, Ramona Schäffer, Lena Rauch-Wirth, Carina Conzelmann, Janis A. Müller, Fabian Zech, Fabian Gerbl, Jana Bleher, Nico Preising, Ludger Ständker, Sebastian Wiese, Dietmar R. Thal, Christian Haupt, Hendrik R. A. Jonker, Manfred Wagner, Elsa Sanchez-Garcia, Tanja Weil, Steffen Stenger, Marcus Fändrich, Jens von Einem, Clarissa Read, Paul Walther, Frank Kirchhoff, Barbara Spellerberg, Jan Münch
Publikováno v:
Cellular and Molecular Life Sciences
Antimicrobial peptides (AMPs) are major components of the innate immune defense. Accumulating evidence suggests that the antibacterial activity of many AMPs is dependent on the formation of amyloid-like fibrils. To identify novel fibril forming AMPs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbe8105cd8417e0164731a868a792e3
https://www.ncbi.nlm.nih.gov/pubmed/37198527
https://www.ncbi.nlm.nih.gov/pubmed/37198527
Autor:
Kübra Kaygisiz, Tanja Weil, Franz J. Mayer, Hans Joachim Räder, Christopher V. Synatschke, Adriana Maria Ender
Publikováno v:
ACS Biomaterials Science & Engineering
Gradients of bioactive molecules play a crucial role in various biological processes like vascularization, tissue regeneration, or cell migration. To study these complex biological systems, it is necessary to control the concentration of bioactive mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dada6817485669381bb55d3672dd460
https://doi.org/10.1021/acsbiomaterials.1c00889
https://doi.org/10.1021/acsbiomaterials.1c00889
Autor:
Kübra Kaygisiz, Adriana M. Ender, Jasmina Gačanin, L. Alix Kaczmarek, Dimitrios A. Koutsouras, Abin N. Nalakath, Pia Winterwerber, Franz J. Mayer, Hans‐Joachim Räder, Tomasz Marszalek, Paul W. M. Blom, Christopher V. Synatschke, Tanja Weil
Publikováno v:
Macromolecular Bioscience
Amyloid-like fibrils are a special class of self-assembling peptides that emerge as a promising nanomaterial with rich bioactivity for applications such as cell adhesion and growth. Unlike the extracellular matrix, the intrinsically stable amyloid-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678a3ecaa3cfe1f1454a62ac82a9d79f
https://pubmed.ncbi.nlm.nih.gov/36281903
https://pubmed.ncbi.nlm.nih.gov/36281903
Publikováno v:
Macromolecules. 53:973-981
A series of dynamic helical homo- and copolymers of chiral and/or achiral biphenylylacetylenes (PBPAs) bearing achiral methoxymethoxy or acetyloxy groups at the 2,2′-positions along with a chiral o...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18c610d1a51a5454456cf89f528a7233
https://doi.org/10.1021/acs.macromol.9b02727
https://doi.org/10.1021/acs.macromol.9b02727
Autor:
Kübra Kaygisiz, Tanja Weil, Adriana Maria Ender, Franz J. Mayer, Christopher V. Synatschke, Hans Joachim Räder
Gradients of bioactive molecules play a crucial role in various biological processes like vascularization, tissue regeneration or cell migration. In order to study these complex biological systems, it is necessary to control the concentration of bioa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41c876badc1b572276aae9b5c50a22e
https://doi.org/10.26434/chemrxiv-2021-rw16l
https://doi.org/10.26434/chemrxiv-2021-rw16l
Publikováno v:
Biomaterials Science
Therapeutic viral gene delivery is an emerging technology which aims to correct genetic mutations by introducing new genetic information to cells either to correct a faulty gene or to initiate cell death in oncolytic treatments. In recent years, sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13dd09df9ef9988218fa81418e1d761
https://pubmed.ncbi.nlm.nih.gov/33025967
https://pubmed.ncbi.nlm.nih.gov/33025967
Autor:
Stefanie Sieste, Manuel Hayn, Thomas Mack, Desiree Schütz, Kübra Kaygisiz, Tuomas P. J. Knowles, Annika Röcker, Edina Lump, Christopher V. Synatschke, Francesco Simone Ruggeri, Frank Kirchhoff, Jan Münch, Tanja Weil, Christoph Meier
Publikováno v:
Advanced Functional Materials 31 (2021) 17
Advanced Functional Materials
Advanced Functional Materials, 31(17)
Advanced Functional Materials
Advanced Functional Materials, 31(17)
Funder: German Research Foundation; Id: http://dx.doi.org/10.13039/501100001659
Amyloid‐like peptide nanofibrils (PNFs) are abundant in nature providing rich bioactivities and playing both functional and pathological roles. The structural feat
Amyloid‐like peptide nanofibrils (PNFs) are abundant in nature providing rich bioactivities and playing both functional and pathological roles. The structural feat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97183afe9822247598e895e555db1031
https://doi.org/10.1002/adfm.202009382
https://doi.org/10.1002/adfm.202009382