Proteometabolomics of initial and recurrent glioblastoma highlights an increased immune cell signature with altered lipid metabolism.

Autor: Cosenza-Contreras M; Institute of Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Schäfer A; Department of Neurosurgery, Philipps University Marburg, Marburg, Germany., Sing J; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada., Cook L; Department of Neurosurgery, Philipps University Marburg, Marburg, Germany., Stillger MN; Institute of Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Chen CY; Institute of Molecular Medicine and Cell Research, University of Freiburg, Freiburg, Germany., Villacorta Hidalgo J; Institute of Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany., Pinter N; Institute of Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany., Meyer L; Institute of Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany., Werner T; Institute of Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany., Bug D; Department of Neurosurgery, Philipps University Marburg, Marburg, Germany., Haberl Z; Department of Neurosurgery, Philipps University Marburg, Marburg, Germany., Kübeck O; Department of Neurosurgery, Philipps University Marburg, Marburg, Germany., Zhao K; Department of Neurosurgery, Philipps University Marburg, Marburg, Germany., Stei S; Department of Neurosurgery, Philipps University Marburg, Marburg, Germany., Gafencu AV; Institute of Cellular Biology and Pathology ' Nicolae Simionescu,' Bucharest, Romania., Ionita R; Institute of Cellular Biology and Pathology ' Nicolae Simionescu,' Bucharest, Romania., Brehar FM; Department of Neurosurgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.; Bagdasar-Arseni' Emergency Clinical Hospital, Bucharest, Romania., Ferrer-Lozano J; Department of Pathology Hospital Universitari i Politècnic La Fe, València, Spain., Ribas G; Biomedical Imaging Research Group (GIBI230) Instituto de Investigación Sanitaria La Fe, Valencia, Spain., Cerdá-Alberich L; Biomedical Imaging Research Group (GIBI230) Instituto de Investigación Sanitaria La Fe, Valencia, Spain., Martí-Bonmatí L; Department of Pathology Hospital Universitari i Politècnic La Fe, València, Spain.; Department of Radiology Hospital Universitari i Politècnic La Fe, València, Spain., Nimsky C; Department of Neurosurgery, Philipps University Marburg, Marburg, Germany., Van Straaten A; Department of medical informatics and evaluation of practices, Assistance Publique-Hôpitaux de Paris Centre, Paris University & European Hospital Georges Pompidou, Paris, France., Biniossek ML; Institute of Molecular Medicine and Cell Research, University of Freiburg, Freiburg, Germany., Föll M; Institute of Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Khoury College of Computer Sciences, Northeastern University, Boston, USA., Cabezas-Wallscheid N; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Büscher J; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Röst H; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada., Arnoux A; Clinical Epidemiology INSERM & Clinical Research Unit, Assistance Publique-Hôpitaux de Paris Centre, Paris University & European Hospital Georges Pompidou, Paris, France., Bartsch JW; Department of Neurosurgery, Philipps University Marburg, Marburg, Germany., Schilling O; Institute of Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany.

Publikováno v: Neuro-oncology [Neuro Oncol] 2024 Mar 04; Vol. 26 (3), pp. 488-502.