Synthesis if new [Y-90]-DOTA based Meleimides for the prelabeling of thiol-bearing L-oligonucleotides and peptides

Autor: Pietzsch, H.-J., Schlesinger, J., Fischer, C., Közle, I., Vonhoff, S., Klussmann, S., Bergmann, R., Steinbach, J.

Publikováno v: 18th International Symposium on Radiopharmaceutical Sciences, 12.-17.07.2009, Edmonton, Canada
Journal of Labelled Compounds and Radiopharmaceuticals 52(2009)Suppl 1, S491

Objectives: A common chelator for radioisotopes of Y and the lanthanides is DOTA. However, the elevated temperatures necessary to achieve sufficient radiochemical yields may be a drawback, especially for the radiolabeling of thermally sensitive molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9556621747aea49eea83613f687ba6bd
https://www.hzdr.de/publications/Publ-13105-1

Small animal PET with hCT-derived cell-penetreting peptides

Autor: Bergmann, R., Közle, I., Neundorf, I.

Publikováno v: 47. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, 22.-25.04.2009, Leipzig, Deutschland
Nuklearmedizin 48(2009)2, A78

Aim: Cell-penetrating peptides (CPP) derived from the native peptide hormone human calcitonin (hCT) represent a high potential drug delivery system for in vivo intracellular targeting of diagnostic and therapeutic compounds. Cell penetration of hCT-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::044c5511a4717638cf2916f529686312
https://www.hzdr.de/publications/Publ-11909-2

Potential of mirror-image oligonucleotides as molecular probes for pretargeting

Autor: Schlesinger, J., Közle, I., Bergmann, R., Klussmann, S., Vonhoff, S., Pietzsch, H.-J.

Publikováno v: XI Turku PET Symposium New Targets in Molecular Imaging, 24.-27.05.2008, Turku, Finland
XI Turku PET Symposium New Targets in Molecular Imaging, 24.-27.05.2008, Turku, FinlandAbstracts of the XI Turku PET Symposium, Kaarina, Finland: Painola, 978-951-29-3563-5, 38

To explore the potential of complementary mirror-image oligonucleotides as recognition systems for pretargeting, the present work deals with radiopharmacological evaluation of an 86Y-labeled 17mer l-DNA and of a hybrid consisting of the radiolabeled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::69bab09171a758e7509f0bdcaa6ec941
https://www.hzdr.de/publications/Publ-12027-1

Pharmacokinetics, biodistribution and toxicology of novel cell-penetrating peptides.

Autor: Reveret, L.^1,2 (AUTHOR), Leclerc, M.^1,2 (AUTHOR), Morin, F.² (AUTHOR), Émond, V.² (AUTHOR), Calon, F.^1,2 (AUTHOR) Frederic.Calon@pha.ulaval.ca

Publikováno v: Scientific Reports. 7/8/2023, Vol. 13 Issue 1, p1-13. 13p.

Magnetic nanoparticles enhance the cellular immune response of dendritic cell tumor vaccines by realizing the cytoplasmic delivery of tumor antigens.

Autor: Huang, Linghong¹ (AUTHOR), Liu, Zonghua¹ (AUTHOR), Wu, Chongjie² (AUTHOR), Lin, Jiansheng³ (AUTHOR) linjiansheng1020@163.com, Liu, Ning² (AUTHOR) liuning@163.com

Publikováno v: Bioengineering & Translational Medicine. Mar2023, Vol. 8 Issue 2, p1-19. 19p.