Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kévin Carvalho"'
Autor:
Thibaut Gauvrit, Hamza Benderradji, Alexandre Pelletier, Soulaimane Aboulouard, Emilie Faivre, Kévin Carvalho, Aude Deleau, Emmanuelle Vallez, Agathe Launay, Anna Bogdanova, Mélanie Besegher, Stéphanie Le Gras, Anne Tailleux, Michel Salzet, Luc Buée, Fabien Delahaye, David Blum, Didier Vieau
Publikováno v:
Nutrients, Vol 15, Iss 21, p 4691 (2023)
Early-life exposure to high-fat diets (HF) can program metabolic and cognitive alterations in adult offspring. Although the hippocampus plays a crucial role in memory and metabolic homeostasis, few studies have reported the impact of maternal HF on t
Externí odkaz:
https://doaj.org/article/cdf71de6faea41f1bf108b58721ec789
Autor:
Edmone Dewaeles, Kévin Carvalho, Sandy Fellah, Jaewon Sim, Nihad Boukrout, Raphaelle Caillierez, Hariharan Ramakrishnan, Cynthia Van der Hauwaert, Jhenkruthi Vijaya Shankara, Nathalie Martin, Noura Massri, Agathe Launay, Joseph K. Folger, Clémentine de Schutter, Romain Larrue, Ingrid Loison, Marine Goujon, Matthieu Jung, Stéphanie Le Gras, Victoria Gomez-Murcia, Emilie Faivre, Julie Lemaire, Anne Garat, Nicolas Beauval, Patrice Maboudou, Viviane Gnemmi, Jean-Baptiste Gibier, Luc Buée, Corinne Abbadie, Francois Glowacki, Nicolas Pottier, Michael Perrais, Rodrigo A. Cunha, Jean-Sébastien Annicotte, Geoffroy Laumet, David Blum, Christelle Cauffiez
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Cisplatin is a potent chemotherapeutic drug that is widely used in the treatment of various solid cancers. However, its clinical effectiveness is strongly limited by frequent severe adverse effects, in particular nephrotoxicity and chemotherapy-induc
Externí odkaz:
https://doaj.org/article/f322febb20a9426fac11bb1c684e29af
Autor:
Hamza Benderradji, Sarra Kraiem, Emilie Courty, Sabiha Eddarkaoui, Cyril Bourouh, Emilie Faivre, Laure Rolland, Emilie Caron, Mélanie Besegher, Frederik Oger, Theo Boschetti, Kévin Carvalho, Bryan Thiroux, Thibaut Gauvrit, Emilie Nicolas, Victoria Gomez-Murcia, Anna Bogdanova, Antonino Bongiovanni, Anne Muhr-Tailleux, Steve Lancel, Kadiombo Bantubungi, Nicolas Sergeant, Jean-Sebastien Annicotte, Luc Buée, Didier Vieau, David Blum, Valérie Buée-Scherrer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Alzheimer’s disease (AD) is the leading cause of dementia. While impaired glucose homeostasis has been shown to increase AD risk and pathological loss of tau function, the latter has been suggested to contribute to the emergence of the glucose home
Externí odkaz:
https://doaj.org/article/67b740be6a384290b9ac72a4124826f9
Autor:
Claire-Marie Dhaenens, Mégane Homa, Kévin Carvalho, Bernard Sablonnière, Vincent Huin, Luc Buée
Publikováno v:
Journal of Caffeine and Adenosine Research
Journal of Caffeine and Adenosine Research, New Rochelle, N.Y. : Mary Ann Liebert, Inc., [2018]-, 2019, 9 (3), pp.73-88. ⟨10.1089/caff.2019.0011⟩
Journal of Caffeine and Adenosine Research, New Rochelle, N.Y. : Mary Ann Liebert, Inc., [2018]-, 2019, 9 (3), pp.73-88. ⟨10.1089/caff.2019.0011⟩
International audience; Adenosine receptors are G-protein-coupled receptors involved in a wide range of physiological and pathological phenomena in most mammalian systems. All four receptors are widely expressed in the central nervous system, where t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88474cd3f06035c058c7b342be8ff34a
Autor:
Isabel, Paiva, Kévin, Carvalho, Patrícia, Santos, Lucrezia, Cellai, Maria Angeliki S, Pavlou, Gaurav, Jain, Thorsten, Gnad, Alexander, Pfeifer, Didier, Vieau, André, Fischer, Luc, Buée, Tiago F, Outeiro, David, Blum
Publikováno v:
GliaREFERENCES. 67(12)
Adenosine A
Autor:
Florian W. Adraoui, Kenza Hettak, Geoffrey Viardot, Magali Alix, Sabrina Guiffard, Benoît Meot, Philippe L’Hostis, Anne Maurin, Eric Delpy, Christophe Drieu La Rochelle, Kevin Carvalho
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1035 (2024)
The available antipsychotics for schizophrenia (SZ) only reduce positive symptoms and do not significantly modify SZ neurobiology. This has raised the question of the robustness and translational value of methods employed during drug development. Ele
Externí odkaz:
https://doaj.org/article/81cb97ec69d3494c9987bca128c30733
Autor:
Ching-Pang Chang, Ya-Gin Chang, Pei-Yun Chuang, Thi Ngoc Anh Nguyen, Kuo-Chen Wu, Fang-Yi Chou, Sin-Jhong Cheng, Hui-Mei Chen, Lee-Way Jin, Kevin Carvalho, Vincent Huin, Luc Buée, Yung-Feng Liao, Chun-Jung Lin, David Blum, Yijuang Chern
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Tau pathology is instrumental in the gradual loss of neuronal functions and cognitive decline in tauopathies, including Alzheimer’s disease (AD). Earlier reports showed that adenosine metabolism is abnormal in the brain of AD patients whil
Externí odkaz:
https://doaj.org/article/8e4c10b7573a4385835d8307e2cb35af
Autor:
Isabel Paiva, Lucrezia Cellai, Céline Meriaux, Lauranne Poncelet, Ouada Nebie, Jean-Michel Saliou, Anne-Sophie Lacoste, Anthony Papegaey, Hervé Drobecq, Stéphanie Le Gras, Marion Schneider, Enas M. Malik, Christa E. Müller, Emilie Faivre, Kevin Carvalho, Victoria Gomez-Murcia, Didier Vieau, Bryan Thiroux, Sabiha Eddarkaoui, Thibaud Lebouvier, Estelle Schueller, Laura Tzeplaeff, Iris Grgurina, Jonathan Seguin, Jonathan Stauber, Luisa V. Lopes, Luc Buée, Valérie Buée-Scherrer, Rodrigo A. Cunha, Rima Ait-Belkacem, Nicolas Sergeant, Jean-Sébastien Annicotte, Anne-Laurence Boutillier, David Blum
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
Caffeine is the most widely consumed psychoactive substance in the world. Strikingly, the molecular pathways engaged by its regular consumption remain unclear. We herein addressed the mechanisms associated with habitual (chronic) caffeine consumption
Externí odkaz:
https://doaj.org/article/180844816fc24e34ba8881f1763587a8
Autor:
Marie J. Pietrowski, Amr Ahmed Gabr, Stanislav Kozlov, David Blum, Annett Halle, Kevin Carvalho
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Purinergic signaling regulates neuronal and glial cell functions in the healthy CNS. In neurodegenerative diseases, purinergic signaling becomes dysregulated and can affect disease-associated phenotypes of glial cells. In this review, we discuss how
Externí odkaz:
https://doaj.org/article/405d6289b2b54d1ab595ab06798209a6
Autor:
Antoine Leboucher, Tariq Ahmed, Emilie Caron, Anne Tailleux, Sylvie Raison, Aurélie Joly-Amado, Elodie Marciniak, Kevin Carvalho, Malika Hamdane, Kadiombo Bantubungi, Steve Lancel, Sabiha Eddarkaoui, Raphaelle Caillierez, Emmanuelle Vallez, Bart Staels, Didier Vieau, Detlef Balschun, Luc Buee, David Blum
Publikováno v:
Neurobiology of Disease, Vol 125, Iss , Pp 14-22 (2019)
Accumulation of hyper-phosphorylated and aggregated Tau proteins is a neuropathological hallmark of Alzheimer's Disease (AD) and Tauopathies. AD patient brains also exhibit insulin resistance. Whereas, under normal physiological conditions insulin si
Externí odkaz:
https://doaj.org/article/1e5dc71246064ca998b489ffffebbd64