Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kåre Gotschalck, Sunesen"'
Autor:
Amanda Frydendahl Boll Johansen, Christine Gaasdal Kassentoft, Michael Knudsen, Maria Bach Laursen, Anders Husted Madsen, Lene Hjerrild Iversen, Kåre Gotschalck Sunesen, Mads Heilskov Rasmussen, Claus Lindbjerg Andersen
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Microsatellite instability (MSI), resulting from a defective mismatch repair system, occurs in approximately 15% of sporadic colorectal cancers (CRC). Since MSI is associated with a poor response to 5-fluorouracile based chemother
Externí odkaz:
https://doaj.org/article/90060eda57db48bc8f45e239d40eccb9
Autor:
Simon Ladefoged Rasmussen, Henrik Bygum Krarup, Kåre Gotschalck Sunesen, Martin Berg Johansen, Mogens Tornby Stender, Inge Søkilde Pedersen, Poul Henning Madsen, Ole Thorlacius-Ussing
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180809 (2017)
Colorectal cancer (CRC) is one of the most common cancers in the western world. Screening is an efficient method of reducing cancer-related mortality. Molecular biomarkers for cancer in general and CRC in particular have been proposed, and hypermethy
Externí odkaz:
https://doaj.org/article/6e0889350fe246a4933a2a2a43639581
Autor:
Jakob W Hendel, Ib Jarle Christensen, Thore Hillig, Søren Brandsborg, Kåre Gotschalck Sunesen, Mathias Mertz-Petersen, Berit Andersen, Mogens Madsen, Michael Klærke, Morten Rasmussen, Ali Kahlid, Hans Jørgen Nielsen, Jakob Kleif, Erland J Erlandsen, Jesper Vilandt, Anders Husted Madsen, Claus L. Andersen, Karina Willemoes, Lars N. Jorgensen, Thomas B. Piper, Linnea Ferm, Nete Hornung
Publikováno v:
Mertz-Petersen, M, Piper, T B, Kleif, J, Ferm, L, Christensen, I J, Nielsen, H J & Danish Collaborative Group on Early Detection of Colorectal Neoplasia 2018, ' Triage for selection to colonoscopy? ', European Journal of Surgical Oncology, vol. 44, no. 10, pp. 1539-1541 . https://doi.org/10.1016/j.ejso.2018.06.013
Implementation of population screening for colorectal cancer by direct colonoscopy or follow-up colonoscopy after a positive fecal blood test has challenged the overall capacity of bowel examinations. Certain countries are facing serious colonoscopy
Autor:
Anders Husted Madsen, Maria Bach Laursen, Claus L. Andersen, Michael Knudsen, Kåre Gotschalck Sunesen, Amanda Frydendahl Boll Johansen, Mads Rasmussen, Lene Hjerrild Iversen, Christine Gaasdal Kassentoft
Publikováno v:
BMC Cancer
Johansen, A F B, Kassentoft, C G, Knudsen, M, Laursen, M B, Madsen, A H, Iversen, L H, Sunesen, K G, Rasmussen, M H & Andersen, C L 2019, ' Validation of computational determination of microsatellite status using whole exome sequencing data from colorectal cancer patients ', BMC Cancer, vol. 19, no. 1, 971 . https://doi.org/10.1186/s12885-019-6227-7
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Johansen, A F B, Kassentoft, C G, Knudsen, M, Laursen, M B, Madsen, A H, Iversen, L H, Sunesen, K G, Rasmussen, M H & Andersen, C L 2019, ' Validation of computational determination of microsatellite status using whole exome sequencing data from colorectal cancer patients ', BMC Cancer, vol. 19, no. 1, 971 . https://doi.org/10.1186/s12885-019-6227-7
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Background Microsatellite instability (MSI), resulting from a defective mismatch repair system, occurs in approximately 15% of sporadic colorectal cancers (CRC). Since MSI is associated with a poor response to 5-fluorouracile based chemotherapy and i
Autor:
Thomas Reinert, Katrine Stribolt, Zoe June Assaf, Lene Hjerrild Iversen, Matthew Rabinowitz, Ryan Swenerton, Ramya Srinivasan, Samantha Navarro, Lars Dyrskjøt, Claus L. Andersen, Tenna V Henriksen, Anne-Sofie Kannerup, Søren Vang, Alexander Olson, Shruti Goel, Alexey Aleshin, Michael Knudsen, Scott Dashner, Styrmir Sigurjonsson, Mustafa Balcioglu, Emil Christensen, Anders Husted Madsen, Cheng-Ho Jimmy Lin, Raheleh Salari, Paul Billings, Himanshu Sethi, Søren Krag, Mads Rasmussen, Søren Laurberg, Shruti Sharma, Bernhard Zimmermann, Svetlana Shchegrova, Amanda Frydendahl Boll Johansen, Antony Tin, Dina Hafez, Hsin-Ta Wu, Iver Nordentoft, Kåre Gotschalck Sunesen
Publikováno v:
Reinert, T, Henriksen, T V, Christensen, E, Sharma, S, Salari, R, Sethi, H, Knudsen, M, Nordentoft, I, Wu, H-T, Tin, A S, Heilskov Rasmussen, M, Vang, S, Shchegrova, S, Frydendahl Boll Johansen, A, Srinivasan, R, Assaf, Z, Balcioglu, M, Olson, A, Dashner, S, Hafez, D, Navarro, S, Goel, S, Rabinowitz, M, Billings, P, Sigurjonsson, S, Dyrskjøt, L, Swenerton, R, Aleshin, A, Laurberg, S, Husted Madsen, A, Kannerup, A-S, Stribolt, K, Palmelund Krag, S, Iversen, L H, Gotschalck Sunesen, K, Lin, C-H J, Zimmermann, B G & Lindbjerg Andersen, C 2019, ' Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer ', JAMA Oncology, vol. 5, no. 8, pp. 1124-1131 . https://doi.org/10.1001/jamaoncol.2019.0528
Importance: Novel sensitive methods for detection and monitoring of residual disease can improve postoperative risk stratification with implications for patient selection for adjuvant chemotherapy (ACT), ACT duration, intensity of radiologic surveill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59acf069d0b5229abc11521aab11d94
https://pure.au.dk/ws/files/197692926/jamaoncology_reinert_2019_oi_190019.pdf
https://pure.au.dk/ws/files/197692926/jamaoncology_reinert_2019_oi_190019.pdf
Autor:
Sarah Østrup Jensen, Mogens Madsen, Ib Jarle Christensen, Mai-Britt Worm Ørntoft, Nadia Øgaard, Anders Husted Madsen, Mads Rasmussen, Kåre Gotschalck Sunesen, Peter Mouritzen, Lene Hjerrild Iversen, Helle Kristensen, Jesper B. Bramsen, Søren Laurberg, Claus L. Andersen, Hans Jørgen Nielsen
Publikováno v:
Jensen, S Ø, Øgaard, N, Ørntoft, M-B W, Rasmussen, M H, Bramsen, J B, Kristensen, H, Mouritzen, P, Madsen, M R, Madsen, A H, Sunesen, K G, Iversen, L H, Laurberg, S, Christensen, I J, Nielsen, H J & Andersen, C L 2019, ' Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer : a clinical biomarker discovery and validation study ', Clinical Epigenetics, vol. 11, 158 . https://doi.org/10.1186/s13148-019-0757-3
Jensen, S Ø, Øgaard, N, Ørntoft, M B W, Rasmussen, M H, Bramsen, J B, Kristensen, H, Mouritzen, P, Madsen, M R, Madsen, A H, Sunesen, K G, Iversen, L H, Laurberg, S, Christensen, I J, Nielsen, H J & Andersen, C L 2019, ' Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer-A clinical biomarker discovery and validation study ', Clinical Epigenetics, vol. 11, no. 1, 158 . https://doi.org/10.1186/s13148-019-0757-3
Clinical Epigenetics
Jensen, S Ø, Øgaard, N, Ørntoft, M B W, Rasmussen, M H, Bramsen, J B, Kristensen, H, Mouritzen, P, Madsen, M R, Madsen, A H, Sunesen, K G, Iversen, L H, Laurberg, S, Christensen, I J, Nielsen, H J & Andersen, C L 2019, ' Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer-A clinical biomarker discovery and validation study ', Clinical Epigenetics, vol. 11, no. 1, 158 . https://doi.org/10.1186/s13148-019-0757-3
Clinical Epigenetics
Background Early detection plays an essential role to reduce colorectal cancer (CRC) mortality. While current screening methods suffer from poor compliance, liquid biopsy-based strategies for cancer detection is rapidly gaining promise. Here, we desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a364e74cdcdd7c9eaee3aa124a5d31
https://curis.ku.dk/ws/files/236269018/document_12_.pdf
https://curis.ku.dk/ws/files/236269018/document_12_.pdf
Autor:
Kåre Gotschalck Sunesen, Poul Henning Madsen, Inge Søkilde Pedersen, Mogens Tornby Stender, Ole Thorlacius-Ussing, Henrik Krarup, Martin Berg Johansen, Simon Ladefoged Rasmussen
Publikováno v:
Colorectal Disease. 18:44-125
Publikováno v:
Colorectal Disease. 18:15-26
Autor:
Henrik Krarup, Martin Berg Johansen, Ole Thorlacius-Ussing, Kåre Gotschalck Sunesen, Inge Søkilde Pedersen, Poul Henning Madsen, Simon Ladefoged Rasmussen, Mogens Tornby Stender
Publikováno v:
Oncotarget
Rasmussen, S L, Krarup, H B, Sunesen, K G, Johansen, M B, Stender, M T, Pedersen, I S, Madsen, P H & Thorlacius-Ussing, O 2018, ' The prognostic efficacy of cell-free DNA hypermethylation in colorectal cancer ', OncoTarget, vol. 9, no. 6, pp. 7010-7022 . https://doi.org/10.18632/oncotarget.24097
Rasmussen, S L, Krarup, H B, Sunesen, K G, Johansen, M B, Stender, M T, Pedersen, I S, Madsen, P H & Thorlacius-Ussing, O 2018, ' The prognostic efficacy of cell-free DNA hypermethylation in colorectal cancer ', OncoTarget, vol. 9, no. 6, pp. 7010-7022 . https://doi.org/10.18632/oncotarget.24097
// Simon Ladefoged Rasmussen 1, 2, 3 , Henrik Bygum Krarup 2, 4 , Kare Gotschalck Sunesen 1 , Martin Berg Johansen 5 , Mogens Tornby Stender 1 , Inge Sokilde Pedersen 2, 4 , Poul Henning Madsen 2, 4 and Ole Thorlacius-Ussing 1, 2, 3 1 Department of G
Publikováno v:
Motavaf, E, Sunesen, K G, Stender, M T & Thorlacius-Ussing, O 2014, ' Prognostic value of preoperative D-dimer and carcinoembryonic antigen levels in patients undergoing intended curative resection for colorectal cancer : a prospective cohort study ', International Journal of Colorectal Disease, vol. 29, no. 11, pp. 1427-1432 . https://doi.org/10.1007/s00384-014-2000-1
PURPOSE: Carcinoembryonic antigen (CEA) has limited value as an isolated predictor for survival among colorectal cancer (CRC) patients. D-dimer (DD) is a strong predictor of survival among metastatic CRC patients, but the prognostic value in non-meta