Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Käthe Bersiner"'
Autor:
Daniel Jacko, Kirill Schaaf, Thorben Aussieker, Lukas Masur, Jonas Zacher, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Desmin intermediate filaments play a crucial role in stress transmission and mechano-protection. The loss of its integrity triggers myofibril breakdown and muscle atrophy for which desmin phosphorylation (pDes) is a priming factor. We invest
Externí odkaz:
https://doaj.org/article/a0f26e8a77b749ea947bbed1382c151c
Autor:
Rebekka J.S. Salzmann, Christina Krötz, Tudor Mocan, Lavinia P. Mocan, Cristiana Grapa, Sophia Rottmann, Ramona Reichelt, Cindy M. Keller, Bettina Langhans, Frederik Schünemann, Alexander Pohl, Thomas Böhler, Käthe Bersiner, Marcin Krawczyk, Piotr Milkiewicz, Zeno Sparchez, Frank Lammert, Sebastian Gehlert, Maria A. Gonzalez-Carmona, Arnulf Willms, Christian P. Strassburg, Miroslaw T. Kornek, Leona Dold, Veronika Lukacs-Kornek
Publikováno v:
Hepatology Communications, Vol 8, Iss 3 (2024)
Background:. The level of type-I interferons (IFNs) in primary sclerosing cholangitis (PSC) was investigated to evaluate its association with disease activity and progression. Methods:. Bioactive type-I IFNs were evaluated in a murine model of PSC an
Externí odkaz:
https://doaj.org/article/b4f21a0acd85432c94d22087ad068ef3
Autor:
Daniel Jacko, Lukas Masur, Kirill Schaaf, Jonas Zacher, Käthe Bersiner, Markus deMarées, Wilhelm Bloch, Sebastian Gehlert
Publikováno v:
Physiological Reports, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Lipofuscin (LF) is an intracellular aggregate associated with proteostatic impairments, especially prevalent in nondividing skeletal muscle fibers. Reactive oxygen species (ROS) drive LF‐formation. Resistance training (RT) improves muscle
Externí odkaz:
https://doaj.org/article/9de2453f360d4e1a83e0ee1c69311207
Autor:
Daniel Jacko, Käthe Bersiner, Gerrit Friederichs, Patrick Ritter, Linnea Nirenberg, Jan Eisenbraun, Markus de Marées, Wilhelm Bloch, Sebastian Gehlert
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199307 (2018)
Skeletal muscle fatigue has been shown to be associated with hyperphosphorylation of the ryanodine receptor 1 at serine 2843 (pRyR1Ser2843), due to chronic overloading exercise. We investigated whether pRyR1Ser2843, is a mechanism relevant for muscle
Externí odkaz:
https://doaj.org/article/be4bb5cef66a42fda75ec4ef1170fc45
Autor:
Sebastian Gehlert, Oliver Schulz, Willhelm Bloch, Fabian Spahiu, Jörg Höhfeld, Daniel Jacko, Käthe Bersiner, Axel Przyklenk
Publikováno v:
American Journal of Physiology-Cell Physiology. 319:C300-C312
Skeletal muscle is a target of contraction-induced loading (CiL), leading to protein unfolding or cellular perturbations, respectively. While cytoskeletal desmin is responsible for ongoing structural stabilization, in the immediate response to CiL, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629aca3d8a086f947b9547021dcf492d
https://doi.org/10.1152/ajpcell.00087.2020
https://doi.org/10.1152/ajpcell.00087.2020
Autor:
Jonas Hebchen, Wilhelm Bloch, Markus de Marées, Daniel Jacko, Käthe Bersiner, Sebastian Gehlert
Publikováno v:
Journal of Applied Physiology. 126:1607-1618
αB-crystallin (CRYAB) is an important actor in the immediate cell stabilizing response following mechanical stress in skeletal muscle. Yet, only little is known regarding myofiber type-specific stress responses of CRYAB. We investigated whether the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2dbbab54ec3af027206cf240416700
https://doi.org/10.1152/japplphysiol.01038.2018
https://doi.org/10.1152/japplphysiol.01038.2018
Publikováno v:
Nutrients
Nutrients, Vol 13, Iss 3884, p 3884 (2021)
Nutrients, Vol 13, Iss 3884, p 3884 (2021)
Muscular adaptations can be triggered by exercise and diet. As vegan and vegetarian diets differ in nutrient composition compared to an omnivorous diet, a change in dietary regimen might alter physiological responses to physical exercise and influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d214e57fc7676261c81849c8d77492d9
https://doi.org/10.3390/nu13113884
https://doi.org/10.3390/nu13113884
Autor:
Markus de Marées, Linnea Nirenberg, Sebastian Gehlert, Patrick Ritter, Gerrit Friederichs, Jan Eisenbraun, Daniel Jacko, Käthe Bersiner, Wilhelm Bloch
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 6, p e0199307 (2018)
PLoS ONE, Vol 13, Iss 6, p e0199307 (2018)
Skeletal muscle fatigue has been shown to be associated with hyperphosphorylation of the ryanodine receptor 1 at serine 2843 (pRyR1Ser2843), due to chronic overloading exercise. We investigated whether pRyR1Ser2843, is a mechanism relevant for muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef5d9c51757af7cacf8462737b1866d
https://pubmed.ncbi.nlm.nih.gov/29953482
https://pubmed.ncbi.nlm.nih.gov/29953482