Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kärt Varendi"'
Autor:
Anmol Kumar, Jaakko Kopra, Kärt Varendi, Lauriina L Porokuokka, Anne Panhelainen, Satu Kuure, Pepin Marshall, Nina Karalija, Mari-Anne Härma, Carolina Vilenius, Kersti Lilleväli, Triin Tekko, Jelena Mijatovic, Nita Pulkkinen, Madis Jakobson, Maili Jakobson, Roxana Ola, Erik Palm, Maria Lindahl, Ingrid Strömberg, Vootele Võikar, T Petteri Piepponen, Mart Saarma, Jaan-Olle Andressoo
Publikováno v:
PLoS Genetics, Vol 12, Iss 1, p e1005808 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1005710.].
Externí odkaz:
https://doaj.org/article/758f22d521a842cdbb2b4a44423a1884
Autor:
Anmol Kumar, Jaakko Kopra, Kärt Varendi, Lauriina L Porokuokka, Anne Panhelainen, Satu Kuure, Pepin Marshall, Nina Karalija, Mari-Anne Härma, Carolina Vilenius, Kersti Lilleväli, Triin Tekko, Jelena Mijatovic, Nita Pulkkinen, Madis Jakobson, Maili Jakobson, Roxana Ola, Erik Palm, Maria Lindahl, Ingrid Strömberg, Vootele Võikar, T Petteri Piepponen, Mart Saarma, Jaan-Olle Andressoo
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005710 (2015)
Degeneration of nigrostriatal dopaminergic system is the principal lesion in Parkinson's disease. Because glial cell line-derived neurotrophic factor (GDNF) promotes survival of dopamine neurons in vitro and in vivo, intracranial delivery of GDNF has
Externí odkaz:
https://doaj.org/article/97fe460db77842808cd04bfe6e27a58c
Autor:
Kärt Varendi, Mikko Airavaara, Jenni Anttila, Sarah Vose, Anu Planken, Mart Saarma, James R Mitchell, Jaan-Olle Andressoo
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93911 (2014)
Stroke is a major complication of cardiovascular surgery, resulting in over 100,000 deaths and over a million postoperative encephalopathies annually in the US and Europe. While mitigating damage from stroke after it occurs has proven elusive, opport
Externí odkaz:
https://doaj.org/article/5293dc4e96bf4ba48ff3ec90c436dce7
Publikováno v:
Radiotherapy and Oncology, 124(3), 448-454. ELSEVIER IRELAND LTD
Background and purpose: Recently, stem cell therapy has been proposed to allow regeneration of radiation damaged salivary glands. It has been suggested that glial-cell-derived neurotrophic factor (GDNF) promotes survival of mice salivary gland stem c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea08a2dcb09130bd5a1baf02dcb101e6
https://doi.org/10.1016/j.radonc.2017.07.008
https://doi.org/10.1016/j.radonc.2017.07.008
Autor:
Jaan-Olle Andressoo, Soophie Olfat, Sara af Bjerkén, Heidi Montonen, Jaakko Kopra, Mart Saarma, Lauriina L. Porokuokka, Kärt Varendi, Anne Panhelainen, T. Petteri Piepponen
Publikováno v:
The Journal of Neuroscience. 37:1581-1590
Midbrain dopamine neuron dysfunction contributes to various psychiatric and neurological diseases, including drug addiction and Parkinson's disease. Because of its well established dopaminotrophic effects, the therapeutic potential of glial cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0963f93ecff3c047bce66a2b63f4b59b
https://doi.org/10.1523/jneurosci.1673-16.2016
https://doi.org/10.1523/jneurosci.1673-16.2016
Publikováno v:
Cellular and Molecular Life Sciences
Brain-derived neurotrophic factor (BDNF) is a secreted protein of the neurotrophin family that regulates brain development, synaptogenesis, memory and learning, as well as development of peripheral organs, such as angiogenesis in the heart and postna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e00833d829d3ad110942ba77743cea
https://doi.org/10.1007/s00018-014-1628-x
https://doi.org/10.1007/s00018-014-1628-x
Publikováno v:
Radiotherapy and Oncology. 127:S304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a35a1e628c5e78d125d703efe1f32df0
https://doi.org/10.1016/s0167-8140(18)30892-2
https://doi.org/10.1016/s0167-8140(18)30892-2
Autor:
Carolina Vilenius, Jaan-Olle Andressoo, Kärt Varendi, Jaakko Kopra, Mart Saarma, Anders Björklund, Jesse Lindholm, Eero Castrén, T. Petteri Piepponen, Mari-Anne Härma, Vootele Voikar, Shane Grealish
Glial cell line-derived neurotrophic factor (GDNF) has been tested in clinical trials to treat Parkinson’s disease with promising but variable results. Improvement of therapeutic effectiveness requires solid understanding of the physiological role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3cfce84c11773379f2b32209311041
https://europepmc.org/articles/PMC4878654/
https://europepmc.org/articles/PMC4878654/
Autor:
Triin Tekko, Lauriina L. Porokuokka, Kersti Lilleväli, Nina Karalija, Mart Saarma, Roxana Ola, Kärt Varendi, Anne Panhelainen, Jaan-Olle Andressoo, Carolina Vilenius, Jelena Mijatovic, Pepin Marshall, Maria Lindahl, Anmol Kumar, Mari-Anne Härma, Satu Kuure, Ingrid Strömberg, Vootele Voikar, Maili Jakobson, T. Petteri Piepponen, Madis Jakobson, Erik Palm, Nita Pulkkinen, Jaakko Kopra
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005710 (2015)
PLoS Genetics
PLoS Genetics
Degeneration of nigrostriatal dopaminergic system is the principal lesion in Parkinson’s disease. Because glial cell line-derived neurotrophic factor (GDNF) promotes survival of dopamine neurons in vitro and in vivo, intracranial delivery of GDNF h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcaa3e8378177ef2c66722913d862d8
http://hdl.handle.net/10138/162489
http://hdl.handle.net/10138/162489
Publikováno v:
SpringerPlus
Brain-derived neurotrophic factor (BDNF) regulates multiple biological processes ranging from central nervous system development and function to neuroinflammation and myogenic differentiation and repair. While coordination of BDNF levels is central i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c6264c4aadfd446f2d186d3238a476
http://europepmc.org/articles/PMC4164675
http://europepmc.org/articles/PMC4164675