Zobrazeno 1 - 10
of 268
pro vyhledávání: '"K, Venuprasad"'
Autor:
Amir Kumar Singh, Ritesh Kumar, Jianyi Yin, John F. Brooks II, Mahesh Kathania, Sandip Mukherjee, Jitendra Kumar, Kevin P. Conlon, Venkatesha Basrur, Zhe Chen, Xianlin Han, Lora V. Hooper, Ezra Burstein, K. Venuprasad
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Th17 cells that produce Interleukin IL-17 are pathogenic in many human diseases, including inflammatory bowel disease, but are, paradoxically, essential for maintaining the integrity of the intestinal barrier in a non-inflammatory state. How
Externí odkaz:
https://doaj.org/article/befedf1f83644092980fd717763deaa0
Inner mitochondrial membrane protein Prohibitin 1 mediates Nix-induced, Parkin-independent mitophagy
Autor:
Kibrom M. Alula, Yaritza Delgado-Deida, Rosemary Callahan, Andreas Till, Lucia Underwood, Winston E. Thompson, Rhonda F. Souza, Themistocles Dassopoulos, Joseph Onyiah, K. Venuprasad, Arianne L. Theiss
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Autophagy of damaged mitochondria, called mitophagy, is an important organelle quality control process involved in the pathogenesis of inflammation, cancer, aging, and age-associated diseases. Many of these disorders are associated with alte
Externí odkaz:
https://doaj.org/article/409c2db6f86d4000bd758ce74a53ab92
Autor:
Amir Kumar Singh, Prashant Khare, Abeer Obaid, Kevin P. Conlon, Venkatesha Basrur, Ronald A. DePinho, K. Venuprasad
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Interleukin-17 (IL-17)-secreting CD4 T cells (Th17) are induced by the master transcription factor RORγt, and are important for anti-fungal immunity and inflammatory responses. Here the authors show that Ubc9-mediated SUMOylation of RORγt induces H
Externí odkaz:
https://doaj.org/article/1df8e582f787431da6877b852dc40340
Autor:
Kibrom M. Alula, Dakota N. Jackson, Andrew D. Smith, Daniel S. Kim, Kevin Turner, Elizabeth Odstrcil, Benny A. Kaipparettu, Themistocles Dassopoulos, K. Venuprasad, Linda A. Feagins, Arianne L. Theiss
Publikováno v:
Cells, Vol 10, Iss 6, p 1349 (2021)
Paneth cell defects in Crohn’s disease (CD) patients (called the Type I phenotype) are associated with worse clinical outcomes. Recent studies have implicated mitochondrial dysfunction in Paneth cells as a mediator of ileitis in mice. We hypothesiz
Externí odkaz:
https://doaj.org/article/9a244ebc2520425894a647d83e021d73
Autor:
Luis F Sifuentes-Dominguez, Haiying Li, Ernesto Llano, Zhe Liu, Amika Singla, Ashish S Patel, Mahesh Kathania, Areen Khoury, Nicholas Norris, Jonathan J Rios, Petro Starokadomskyy, Jason Y Park, Purva Gopal, Qi Liu, Shuai Tan, Lillienne Chan, Theodora Ross, Steven Harrison, K Venuprasad, Linda A Baker, Da Jia, Ezra Burstein
Publikováno v:
eLife, Vol 8 (2019)
Inflammatory bowel disease (IBD) affects 1.5–3.0 million people in the United States. IBD is genetically determined and many common risk alleles have been identified. Yet, a large proportion of genetic predisposition remains unexplained. In this st
Externí odkaz:
https://doaj.org/article/dd63f37bb27b42538ad9d4b24982c8fb
Autor:
Arianne L. Theiss, Laurent Désaubry, Rhonda F. Souza, K. Venuprasad, Xuan Wang, Kevin Turner, Redouane Tabti, Yaritza Delgado-Deida, Kibrom M. Alula, Dakota N. Jackson
Colorectal cancer exhibits aberrant activation of Wnt/β-catenin signaling. Many inhibitors of the Wnt/β-catenin pathway have been tested for Wnt-dependent cancers including colorectal cancer, but are unsuccessful due to severe adverse reactions. FL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55906f2feca0c3031efb7c66596c8cb8
https://doi.org/10.1158/0008-5472.c.6512415
https://doi.org/10.1158/0008-5472.c.6512415
Autor:
Arianne L. Theiss, Laurent Désaubry, Rhonda F. Souza, K. Venuprasad, Xuan Wang, Kevin Turner, Redouane Tabti, Yaritza Delgado-Deida, Kibrom M. Alula, Dakota N. Jackson
FL3 does not decrease viability in IEC6 cells compared to standard CRC chemotherapeutic drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045a5323bfa94977f4fe0a459c1a85ca
https://doi.org/10.1158/0008-5472.22426635.v1
https://doi.org/10.1158/0008-5472.22426635.v1
Akademický článek
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Publikováno v:
Inflammasome Biology ISBN: 9780323918022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fb785a3ef7becb59087b9cca984405d
https://doi.org/10.1016/b978-0-323-91802-2.00023-2
https://doi.org/10.1016/b978-0-323-91802-2.00023-2
Autor:
Antonio Abbate, Ivona Aksentijevich, Marcelo Pires Amaral, Magaiver Andrade-Silva, Diego Angosto-Bazarra, Luca Antonioli, Kübra Aral, Juan I. Aróstegui, Jillian Barlow, Laura Benvenuti, Nunzia Bernardini, Massimo Bertinaria, Monika Biasizzo, Karina Ramalho Bortoluci, Dave Boucher, Laura Migliari Branco, David Brough, Petr Broz, Clare E. Bryant, Mark Cahill, Matthew Campbell, Soo Jung Cho, Shelbi Christgen, Rebecca C. Coll, Isabelle Couillin, Brianna Cyr, Sarah Dalmon, Juan Pablo de Rivero Vaccari, Francesco Di Virgilio, Andrea Dorfleutner, Sarah L. Doyle, Vanessa D'Antongiovanni, Ariel E. Feldstein, Matteo Fornai, Carlos García-Palenciano, Simone Gastaldi, Matthias Geyer, François Ghiringhelli, Anna Lisa Giuliani, José Manuel González-Navajas, Iva Hafner-Bratkovič, Shaima'a Hamarsheh, Michael T. Heneka, Thomas Henry, Jun-ichi Hikima, Inga V. Hochheiser, Alexander Hogg, Alexander Hooftman, Christopher Hoyle, Yin Huang, Sarah Huot-Marchand, Laura Hurtado-Navarro, Sushmita Jha, Thirumala-Devi Kanneganti, Benedikt Kaufmann, Andrea D. Kim, Nataša Kopitar-Jerala, Jordana Kron, Silvia Lucena Lage, Beatriz Lozano-Ruiz, Elisabetta Marini, Billie Matchett, Adolfo G. Mauro, Eleonora Mezzaroma, Michael R. Milward, Ingrid Kazue Mizuno Watanabe, Natsuki Morimoto, Sandip Mukherjee, Mar Orzáez, Luke A.J. O'Neill, Pablo Pelegrín, Carolina Pellegrini, Anaïs Perrichet, Joanna Picó, Nicola Potere, Alexander Pronko, Kishore Aravind Ravichandran, Nicolas Riteau, Kim S. Robinson, Cédric Rébé, Fadi N. Salloum, Mónica Sancho, Andrew Sandstrom, Niels Olsen Saraiva Câmara, Florian I. Schmidt, Liang Shan, Eoin Silke, Paula M. Soriano-Teruel, Christian Stehlik, Heather Stout-Delgado, Arianne L. Theiss, Jenny P.-Y. Ting, Stefano Toldo, Elviche L. Tsakem, Rebecca E. Tweedell, Amalia Tzoumpa, K. Venuprasad, Rose Wellens, Robert Zeiser, Franklin L. Zhong, Alessia Zotta
Publikováno v:
Inflammasome Biology ISBN: 9780323918022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1df40277879d3530be000cf63f0ec15f
https://doi.org/10.1016/b978-0-323-91802-2.01002-1
https://doi.org/10.1016/b978-0-323-91802-2.01002-1