Zobrazeno 1 - 10
of 147
pro vyhledávání: '"K, Venkova"'
Publikováno v:
Journal of Pharmacy and Pharmacology. 55:67-75
Human keratinocyte growth factor-2 (KGF-2) is a member of the fibroblast growth factor family that promotes healing of experimental small intestinal ulceration and colitis. The aim of this study was to determine whether repifermin, a truncated form o
Publikováno v:
Pharmacology & Toxicology. 75:129-135
Male Wistar rats were exposed to Pb2+ or Zn2+ and to Pb2+ + Zn2+, receiving Pb(CH3COO)2 or/and ZnSO4 with drinking water for 30 days. Cumulative concentration-effect curves for carbachol were obtained in ileum and trachea isolated from control and he
Autor:
K. Venkova, Jacob Krier
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 266:G40-G47
The actions of NO synthase inhibitors and indomethacin, a cyclooxygenase inhibitor, on the nonadrenergic noncholinergic (NANC) mechanical responses of cat distal colon were studied in vitro using muscle strips orientated in the axis of the longitudin
Publikováno v:
Archives of Toxicology. 67:330-337
Male Wistar rats were exposed to subtoxic doses of Co2+ or Ni2+, receiving Co(NO3)2 or NiSO4 with drinking water for 30 days. No significant differences in the body weight and no visible changes in the behaviour of the controls and experimental anima
Publikováno v:
General Pharmacology: The Vascular System. 22:159-163
1. 1. GABA and GABAergic agonists—muscimol and (±)baclofen changed the spontaneous mechanical activity in isolated cat terminal ileum. 2. 2. GABA at doses ranging from 5 μM to 2 mM produced concentration-dependent biphasic responses consisting of
Publikováno v:
General Pharmacology: The Vascular System. 21:123-126
1. The effects of (D-Ala2, D-Leu5) enkephalin amide (DADLE) on the responses of the cat terminal ileum to field electrical stimulation (pulse duration of 0.5 msec, train duration of 10 sec, 30 V) were evaluated by the changes in the contractile or th
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 18(1)
Tegaserod is a 5-HT(4) receptor partial agonist approved for the treatment of irritable bowel syndrome in women with constipation and in both men and women with chronic constipation. The efficacy of tegaserod is based on the importance of 5-HT(4) rec
Publikováno v:
Digestive diseases and sciences. 47(12)
Our goal was to determine whether Seirogan, an herbal medicine used as an antidiarrheal agent, modifies colonic function, including motility. Experiments were performed on four female Yucatan mini-pigs with established permanent cecal fistulas provid
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(1)
Recombinant human interleukin (rhIL)-11 has anti-inflammatory and protective effects in models of intestinal mucosal injury. Our aim was to investigate whether oral treatment with rhIL-11 reverses functional abnormalities in intestinal muscle contrac
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(1)
HLA-B27 transgenic rats are a model of spontaneous gastrointestinal inflammation associated with expression of human leukocyte antigen (HLA) B27 and beta(2)-microglobulin. Our goal was to investigate in vitro enteric nerve regulation and contractile