Zobrazeno 1 - 10 of 43 pro vyhledávání: '"K, Spekker"'
1
Indoleamine 2,3-Dioxygenase Is Involved in Defense againstNeospora caninumin Human and Bovine Cells
Autor: Walter Däubener, Kathrin Heseler, V. Ince, Markus Czesla, Gereon Schares, Silvia K. Schmidt, K. Spekker
Publikováno v: Infection and Immunity. 77:4496-4501
Neospora caninumis an apicomplexan parasite closely related toToxoplasma gondii. In nature this parasite is found especially in dogs and cattle, but it may also infect other livestock. The growth ofN. caninum, which is an obligate intracellular paras
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643ec136b5b66483afbb68bd61be1481
https://doi.org/10.1128/iai.00310-09
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3
Antimicrobial effects of murine mesenchymal stromal cells directed against Toxoplasma gondii and Neospora caninum: role of immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs)
Autor: Daniel Degrandi, Stuhlsatz S, Jochen Seissler, Andrew Hemphill, Özer Degistirici, Klaus Pfeffer, S. Brunder, V. Ince, Jonathan C. Howard, M. Leineweber, Silvia K. Schmidt, Roland Meisel, K. Spekker, Walter Däubener, Rüdiger V. Sorg, Gereon Schares
Publikováno v: Spekker, K.; Leineweber, M.; Degrandi, D.; Ince, V.; Brunder, S.; Schmidt, S. K.; Stuhlsatz, S.; Howard, J. C.; Schares, G.; Degistirici, O.; Meisel, R.; Sorg, R. V.; Seissler, J.; Hemphill, Andrew; Pfeffer, K.; Däubener, W. (2013). Antimicrobial effects of murine mesenchymal stromal cells directed against Toxoplasma gondii and Neospora caninum: role of immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs). Medical microbiology and immunology, 202(3), pp. 197-206. Springer 10.1007/s00430-012-0281-y
Medical microbiology and immunology
Mesenchymal stromal cells (MSCs) have a multilineage differentiation potential and provide immunosuppressive and antimicrobial functions. Murine as well as human MSCs restrict the proliferation of T cells. However, species-specific differences in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6376dc6c8f3e20596dc7389f58ff4a4
https://boris.unibe.ch/44749/1/art_10.1007_s00430-012-0281-y.pdf
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4
Peptide microarray analysis of in silico-predicted epitopes for serological diagnosis of Toxoplasma gondii infection in humans
Autor: Walter Däubener, Uwe Pleyer, Uwe Groß, Olaf Niederstrasser, Marc Mertens, Sandra Werdermann, Andrea Hotop, Pavlo Maksimov, Eckhardt Petri, Johannes Zerweck, K. Spekker, Gereon Schares, Aline Maksimov, Rainer G. Ulrich, Franz Josef Conraths
Publikováno v: Clinical and vaccine immunology : CVI. 19(6)
Toxoplasma gondii infections occur worldwide in humans and animals. In immunocompromised or prenatally infected humans, T. gondii can cause severe clinical symptoms. The identification of specific epitopes on T. gondii antigens is essential for the i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9eb4b4182efbe244fdfc2734cd1fa27
https://pubmed.ncbi.nlm.nih.gov/22496494
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5
Analysis of clonal type-specific antibody reactions in Toxoplasma gondii seropositive humans from Germany by peptide-microarray
Autor: Pavlo Maksimov, Eckhardt Petri, Sandra Werdermann, Uwe Groß, Aline Maksimov, Olaf Niederstrasser, K. Spekker, Walter Däubener, Andrea Hotop, Johannes Zerweck, Gereon Schares, Franz Josef Conraths, Rainer G. Ulrich, Marc Mertens
Publikováno v: PLoS ONE, Vol 7, Iss 3, p e34212 (2012)
PLoS ONE
BackgroundDifferent clonal types of Toxoplasma gondii are thought to be associated with distinct clinical manifestations of infections. Serotyping is a novel technique which may allow to determine the clonal type of T. gondii humans are infected with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cb5a89e5be584bfe131fb99cb1ddaa
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22470537/?tool=EBI
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6
Prevalence of specific IgG-antibodies against Toxoplasma gondii in domestic turkeys determined by kinetic ELISA based on recombinant GRA7 and GRA8
Autor: Martin Koethe, Birte Zöller, Martina Ludewig, Arwid Daugschies, Amina Bittame, K. Spekker, Karsten Fehlhaber, Reinhard K. Straubinger, S. Pott, Corinne Mercier, Astrid M. Tenter, Berit Bangoura
Publikováno v: Veterinary Parasitology
Veterinary Parasitology, Elsevier, 2011, 180 (3-4), pp.179-90. ⟨10.1016/j.vetpar.2011.03.036⟩
International audience; The protozoan parasite Toxoplasma (T.) gondii is one of the most common zoonotic infectious agents worldwide. Besides its sexual reproduction in cats, T. gondii can also infect a wide spectrum of other warm-blooded animals. Th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ffca791e032331e1bb1141a1a1c02ad
https://hal.archives-ouvertes.fr/hal-00794237
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7
Antimicrobial and immunoregulatory effector mechanisms in human endothelial cells. Indoleamine 2,3-dioxygenase versus inducible nitric oxide synthase
Autor: Kathrin Heseler, Silvia K. Schmidt, K. Spekker, Walter Däubener, Colin R. MacKenzie
Publikováno v: Thrombosis and haemostasis. 102(6)
SummaryIn infectious diseases, interferon-gamma (IFN-γ) is generally accepted as one of the most important inducers of antimicrobial and immunoregulatory effects, and both seemingly contradictory effects, can be mediated by the same effector molecul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957cd2785a745c5ff0c3c9b3fbe63157
https://pubmed.ncbi.nlm.nih.gov/19967141
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9
Antimicrobial and immunoregulatory properties of human tryptophan 2,3-dioxygenase
Autor: Walter Däubener, Claudia Woite, Colin R. MacKenzie, Silvia K. Schmidt, Kathrin Heseler, Anika Müller, K. Spekker
Publikováno v: European journal of immunology. 39(10)
In mammals, the regulation of local tryptophan concentrations by the IFN-gamma-i inducible enzyme IDO is a prominent antimicrobial and immunoregulatory effector mechanism. Here, we show for the first time that another tryptophan-degrading enzyme, the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae6c30f5df989b2b33d02105d143ebf
https://pubmed.ncbi.nlm.nih.gov/19637229
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10
The missing link between indoleamine 2,3-dioxygenase mediated antibacterial and immunoregulatory effects
Autor: Kathrin Heseler, K. Spekker, Walter Däubener, Anika Müller, Silvia K. Schmidt, Colin R. MacKenzie
Publikováno v: Journal of Cellular and Molecular Medicine
The interferon (IFN)-gamma-inducible tryptophan degrading enzyme indoleamine 2,3-dioxygenase (IDO) has not only been recognized as a potent antimicrobial effector molecule for the last 25 years but was recently found also to have potent immunoregulat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcb77f8163aada01701268eb83396cf
https://pubmed.ncbi.nlm.nih.gov/19602041
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