Anxiolytic-like effects of the corticotropin-releasing factor1 (CRF1) antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] administered acutely or chronically at doses occupying central CRF1 receptors in rats.

Autor: Snjezana, Lelas, Harvey, Wong, Yu-Wen, Li, L, Heman Karen, A, Ward Kathryn, L, Zeller Kim, K, Sieracki Kristine, L, Polino Joseph, E, Godonis Helen, X, Ren Shelly, Xiao-Xin, Yan, P, Arneric Stephen, W, Robertson David, R, Hartig Paul, Scott, Grossman, L, Trainor George, A, Taub Rebecca, Robert, Zaczek, J, Gilligan Paul, F, McElroy John

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; April 2004, Vol. 309 Issue: 1 p293-302, 10p