METformin for the MINimization of Geographic Atrophy Progression (METforMIN): A Randomized Trial

Autor: Liangbo Linus Shen, MD, Jeremy D. Keenan, MD, MPH, Noor Chahal, BS, Abu Tahir Taha, BS, Jasmeet Saroya, BS, Chu Jian Ma, MD, Mengyuan Sun, PhD, Daphne Yang, BS, Catherine Psaras, BA, Jacquelyn Callander, MD, Christina Flaxel, MD, Amani A. Fawzi, MD, Thomas K. Schlesinger, MD, PhD, Robert W. Wong, MD, Loh-Shan Bryan Leung, MD, Alexander M. Eaton, MD, Nathan C. Steinle, MD, David G. Telander, MD, Armin R. Afshar, MD, Melissa D. Neuwelt, MD, Jennifer I. Lim, MD, Glenn C. Yiu, MD, PhD, Jay M. Stewart, MD

Publikováno v: Ophthalmology Science, Vol 4, Iss 3, Pp 100440- (2024)

Purpose: Metformin use has been associated with a decreased risk of age-related macular degeneration (AMD) progression in observational studies. We aimed to evaluate the efficacy of oral metformin for slowing geographic atrophy (GA) progression. Desi

Externí odkaz: https://doaj.org/article/ab2d7f3a75e04061a390b96d563e016e

FIRST-YEAR SPECTROSCOPY FOR THE SLOAN DIGITAL SKY SURVEY-II SUPERNOVA SURVEY

Autor: Steven M. Kahn, Jennifer L. Marshall, Mamoru Doi, Changsu Choi, Roger W. Romani, John R. Lucey, Hubert Lampeitl, S. J. Kleinman, Dan Long, D. Cinabro, Jesper Sollerman, Naoki Yasuda, John Marriner, Bruce A. Bassett, Chris A. Collins, Gajus Miknaitis, John C. Barentine, Shannon Watters, Joshua A. Frieman, K. Schlesinger, F. DeJongh, Chen Zheng, Andrew C. Becker, Giorgos Leloudas, Craig J. Hogan, Ryan J. Foley, Darren L. DePoy, Naohiro Takanashi, Tomoki Morokuma, Stephanie A. Snedden, Viktor Malanushenko, Peter M. Garnavich, Yutaka Ihara, Richard Kessler, Linda C. Watson, Roberto J. Assef, Saurabh Jha, Kaike Pan, Kouichi Tokita, Jurek Krzesinski, Ralf Bender, Mathew Smith, Ed Elson, Stephan Frank, Ben Dilday, Linda Ostman, Ulrich Hopp, Atsuko Nitta, Alastair C. Edge, Donald P. Schneider, Christopher W. Morgan, G. Saurage, Robert C. Nichol, A. Kathy Romer, Wolfram Kollatschny, Jon A. Holtzman, Adam G. Riess, Michael Richmond, Arlin P. S. Crotts, D. McGinnis, Russet McMillan, Jack Dembicky, Howard Brewington, Donald G. York, Roger Blandford, Jason D. Eastman, J. Craig Wheeler, J. L. Prieto, Elena Malanushenko, Malcolm N. Bremer, Masao Sako, Kohki Konishi, William Ketzeback, Alexei V. Filippenko, Kurt van der Heyden, Michael E. Eyler, Michael Harvanek, Myungshin Im, Maximilian Stritzinger, Ariel Goobar

Publikováno v: Zheng, C, Romani, R W, Sako, M, Marriner, J P, Bassett, B A, Becker, A C, Choi, C, Cinabro, D, Dejongh, F, Depoy, D L, Dilday, B, Doi, M, Frieman, J A, Garnavich, P M, Hogan, C J, Holtzman, J A, Im, M, Jha, S W, Kessler, R, Konishi, K, Lampeitl, H, Marshall, J L, McGinnis, D, Miknaitis, G, Nichol, R C, Prieto, J L, Riess, A G, Richmond, M W, Schneider, D P, Smith, M, Takanashi, N, Tokita, K, van der Heyden, K J, Yasuda, N, Assef, R J, Barentine, J C, Bender, R, Blandford, R D, Bremer, M, Brewington, H J, Collins, C A, Crotts, A, Dembicky, J, Eastman, J, Edge, A C, Elson, E, Eyler, M E, Filippenko, A V, Foley, R J, Frank, S, Goobar, A, Harvanek, M, Hopp, U, Ihara, Y, Kahn, S, Ketzeback, W, Kleinman, S J, Kollatschny, W, Krzesinski, J, Leloudas, G, Long, D C, Lucey, J, Malanushenko, E, Malanushenko, V, McMillan, R J, Morgan, C W, Morokuma, T, Nitta, A, Ostman, L, Pan, K, Romer, A K, Saurage, G, Schlesinger, K J, Snedden, S A, Sollerman, J, Stritzinger, M D, Watson, L C, Watters, S, Wheeler, J C & York, D G 2008, ' First-year spectroscopy for the Sloan Digital Sky Survey-II supernova survey ', The Astronomical Journal, vol. 135, no. 5, pp. 1766-1784 . https://doi.org/10.1088/0004-6256/135/5/1766
Astronomical journal, 2008, Vol.135(5), pp.1766-1784 [Peer Reviewed Journal]

This paper presents spectroscopy of supernovae discovered in the first season of the Sloan Digital Sky Survey-II Supernova Survey. This program searches for and measures multi-band light curves of supernovae in the redshift range z = 0.05 - 0.4, comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e09274e99910a5a2ac1715bec8cdc1e
https://doi.org/10.1088/0004-6256/135/5/1766

A rare case of primary lung adenocarcinoma detected by routine liquid-based cervical cytology

Autor: P. Mahadevia, Missak Haigentz, A. R. Berman, Vineet R. Jain, A. M. Khan, K. Schlesinger

Publikováno v: Lung Cancer. 58:282-285

Cervical cytology is mainly used for the screening and detection of early cervical cancers and its precursors. Rarely, detection of malignant cells in cervical cytology specimens is the first manifestation of an extrauterine (EU) malignancy. We repor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35891deb187c447fec51a0c6d6f3fe4f
https://doi.org/10.1016/j.lungcan.2007.04.017

Apoptosis Stimulated by the 91-kDa Caspase Cleavage MEKK1 Fragment Requires Translocation to Soluble Cellular Compartments

Autor: Matthew B. Jarpe, Gary L. Johnson, Thomas K. Schlesinger, Christian Widmann, Gary R. Fanger, Christelle Bonvin, Jean-René Cardinaux

Publikováno v: Journal of Biological Chemistry. 277:10283-10291

MEKK1, a 196-kDa mitogen-activated protein kinase (MAPK) kinase kinase, generates anti-apoptotic signaling as a full-length protein but induces apoptosis when cleaved by caspases. Here, we show that caspase-dependent cleavage of MEKK1 relocalizes the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2411c2c5fb973c6b553ac1edb5362f75
https://doi.org/10.1074/jbc.m106885200

Topics in the History of Psychology

Autor: G. A. Kimble, K. Schlesinger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76b7acd7da829f3036df3aeac020a4f1
https://doi.org/10.4324/9781315802633