CF2H as hydrogen bond donor group for the fine tuning of peptide bond geometry with difluoromethylated pseudoprolines

Autor: Grégory Chaume, Thierry Brigaud, N. Malquin, Emeric Miclet, Nathalie Lensen, K. Rahgoshay

Publikováno v: Chemical Communications
Chemical Communications, 2019, 55 (83), pp.12487-12490. ⟨10.1039/C9CC05771D⟩

International audience; CF2H-Pseudoprolines obtained from difluoroacetaldehyde hemiacetal and serine are stable proline surrogates. The consequence of the incorporation of the CF2H group is an important decrease of the trans to cis amide bond isomeri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1ac2751c099c7cf35e2ab6d1f74ed4
https://hal.science/hal-03549249

Catalytic Difluoromethylation of Alkenes with Difluoroacetic Anhydride: Reactivity of Fluorinated Diacyl Peroxides and Radicals.

Autor: Tagami, Takuma¹ (AUTHOR), Mitani, Yusuke^2,3 (AUTHOR), Kawamura, Shintaro^1,2 (AUTHOR) skawamura@riken.jp, Sodeoka, Mikiko^1,2,3 (AUTHOR) sodeoka@riken.jp

Publikováno v: Advanced Synthesis & Catalysis. 11/7/2023, Vol. 365 Issue 21, p3637-3647. 11p.

Incorporation of CF3-pseudoprolines into polyproline type II foldamers confers promising biophysical features.

Autor: Cayrou, Chloé, Walrant, Astrid, Ravault, Delphine, Guitot, Karine, Noinville, Sylvie, Sagan, Sandrine, Brigaud, Thierry, Gonzalez, Simon, Ongeri, Sandrine, Chaume, Grégory

Publikováno v: Chemical Communications; 8/21/2024, Vol. 60 Issue 65, p8609-8612, 4p

Focus on Physico-Chemical Properties of Sulfoximines: Acidity, Basicity and Lipophilicity.

Autor: Anselmi E; Faculté des Sciences & Techniques, Université de Tours, 37200, Tours, France.; Institut Lavoisier de Versailles, Université Paris-Saclay, UVSQ, CNRS, UMR 8180, 78000, Versailles, France., Montigny B; PCM2E EA 6299, Université de Tours, Parc de Grandmont, 37200, Tours, France., Lõkov M; Institute of Chemistry, University of Tartu, Ravila 14a Str, Tartu, 50411, Estonia., Kesküla C; Institute of Chemistry, University of Tartu, Ravila 14a Str, Tartu, 50411, Estonia., Soosaar JE; Institute of Chemistry, University of Tartu, Ravila 14a Str, Tartu, 50411, Estonia., Tshepelevitsh S; Institute of Chemistry, University of Tartu, Ravila 14a Str, Tartu, 50411, Estonia., Billard T; Institute of Chemistry and Biochemistry (ICBMS-UMR CNRS5246), CNRS, Université Lyon 1, CPE Lyon, 1 rue Victor Grignard, 69622, Lyon, France., Magnier E; Institut Lavoisier de Versailles, Université Paris-Saclay, UVSQ, CNRS, UMR 8180, 78000, Versailles, France., Leito I; Institute of Chemistry, University of Tartu, Ravila 14a Str, Tartu, 50411, Estonia.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Oct 27, pp. e202402329. Date of Electronic Publication: 2024 Oct 27.

The ¹⁸ F-Difluoromethyl Group: Challenges, Impact and Outlook.

Autor: Ford J; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, United Kingdom., Ortalli S; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, United Kingdom., Gouverneur V; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, United Kingdom.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Jun 21; Vol. 63 (26), pp. e202404957. Date of Electronic Publication: 2024 May 15.