Zobrazeno 1 - 10
of 178
pro vyhledávání: '"K, Podell"'
Autor:
Taru S. Dutt, John S. Spencer, Burton R. Karger, Amy Fox, Andres Obregon-Henao, Brendan K. Podell, G. Brooke Anderson, Marcela Henao-Tamayo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Enzyme-linked immunosorbent assay (ELISA) is a technique to detect the presence of an antigen or antibody in a sample. ELISA is a simple and cost-effective method that has been used for evaluating vaccine efficacy by detecting the presence of antibod
Externí odkaz:
https://doaj.org/article/e541c6d127904cffbb00ec9adaec42d7
Autor:
Sarah K. Cooper, David Forrest Ackart, Faye Lanni, Marcela Henao-Tamayo, G. Brooke Anderson, Brendan K. Podell
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The control of bacterial growth is key to the prevention and treatment of tuberculosis (TB). Granulomas represent independent foci of the host immune response that present heterogeneous capacity for control of bacterial growth. At the whole tissue le
Externí odkaz:
https://doaj.org/article/d3abf1a56ca54c45854449446b7414b0
Autor:
Brittany D. Williams, Debora Ferede, Hazem F. M. Abdelaal, Bryan J. Berube, Brendan K. Podell, Sasha E. Larsen, Susan L. Baldwin, Rhea N. Coler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
At the beginning of the COVID-19 pandemic those with underlying chronic lung conditions, including tuberculosis (TB), were hypothesized to be at higher risk of severe COVID-19 disease. However, there is inconclusive clinical and preclinical data to c
Externí odkaz:
https://doaj.org/article/aff08b3a575940cbbf9ef16b41cab381
Autor:
Amanda S. Latham, Charlize E. Geer, David F. Ackart, Isla K. Anderson, Kaley M. Vittoria, Brendan K. Podell, Randall J. Basaraba, Julie A. Moreno
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Tuberculosis, caused by Mycobacterium tuberculosis infection, is an ongoing epidemic with an estimated ten million active cases of the disease worldwide. Pulmonary tuberculosis is associated with cognitive and memory deficits, and patients with this
Externí odkaz:
https://doaj.org/article/0dc3cb2aa699433f855868582cd2883e
Autor:
Susan L. Baldwin, Valerie A. Reese, Sasha E. Larsen, Tiffany Pecor, Bryan P. Brown, Brian Granger, Brendan K. Podell, Christopher B. Fox, Steven G. Reed, Rhea N. Coler
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Mycobacterium tuberculosis (M.tb) has led to approximately 1.3 million deaths globally in 2020 according to the World Health Organization (WHO). More effective treatments are therefore required to prevent the transmission of M.tb. Although Bacille Ca
Externí odkaz:
https://doaj.org/article/699e1361e91840d39815fe328c717453
Autor:
Nicholas D. Walter, Sarah E. M. Born, Gregory T. Robertson, Matthew Reichlen, Christian Dide-Agossou, Victoria A. Ektnitphong, Karen Rossmassler, Michelle E. Ramey, Allison A. Bauman, Victor Ozols, Shelby C. Bearrows, Gary Schoolnik, Gregory Dolganov, Benjamin Garcia, Emmanuel Musisi, William Worodria, Laurence Huang, J. Lucian Davis, Nhung V. Nguyen, Hung V. Nguyen, Anh T. V. Nguyen, Ha Phan, Carol Wilusz, Brendan K. Podell, N’ Dira Sanoussi, Bouke C. de Jong, Corinne S. Merle, Dissou Affolabi, Helen McIlleron, Maria Garcia-Cremades, Ekaterina Maidji, Franceen Eshun-Wilson, Brandon Aguilar-Rodriguez, Dhuvarakesh Karthikeyan, Khisimuzi Mdluli, Cathy Bansbach, Anne J. Lenaerts, Radojka M. Savic, Payam Nahid, Joshua J. Vásquez, Martin I. Voskuil
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
It is unclear why different antibiotics vary in their ability to shorten treatment of tuberculosis. Here, the authors show that a measure based on ribosomal RNA synthesis in Mycobacterium tuberculosis correlates with treatment shortening in culture,
Externí odkaz:
https://doaj.org/article/e0c6c2c659ca434dbad834a1759cfbb7
Autor:
Sara E. Maloney, Ian E. Stewart, Brendan K. Podell, Hadley E. Gary, Jeffrey B. Mecham, Bryan J. Berube, Susan L. Baldwin, Rhea N. Coler, Anthony J. Hickey
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 729 (2023)
Mycobacterium tuberculosis (M.tb) has infected one-quarter of the world’s population and led to the deaths of 1.6 million individuals in 2021 according to estimates from the World Health Organization. The rise in prevalence of multidrug-resistant a
Externí odkaz:
https://doaj.org/article/fb1e73021b01468fbe479f08053d7b07
Autor:
Sasha E. Larsen, Valerie A. Reese, Tiffany Pecor, Bryan J. Berube, Sarah K. Cooper, Guy Brewer, Diane Ordway, Marcela Henao-Tamayo, Brendan K. Podell, Susan L. Baldwin, Rhea N. Coler
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The nontuberculous mycobacteria (NTM) Mycobacterium avium is a clinically significant pathogen that can cause a wide range of maladies, including tuberculosis-like pulmonary disease. An immunocompromised host status, either genetically or ac
Externí odkaz:
https://doaj.org/article/927dd0386d3f47ee8d7c92fa46bca032
Autor:
Brendan K. Podell, David F. Ackart, Michael A. Richardson, James E. DiLisio, Bruce Pulford, Randall J. Basaraba
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 2, Pp 151-162 (2017)
Type 2 diabetes is a leading cause of morbidity and mortality among noncommunicable diseases, and additional animal models that more closely replicate the pathogenesis of human type 2 diabetes are needed. The goal of this study was to develop a model
Externí odkaz:
https://doaj.org/article/70216dc32b294770a9becb5408d2cc50
Autor:
Macallister C. Harris, Hadley E. Gary, Sarah K. Cooper, David F. Ackart, James E. Dilisio, Randall J Basaraba, Tan-Yun Cheng, Ildiko van Rhijn, D. Branch Moody, Brendan K. Podell
Publikováno v:
bioRxiv
CD1 is an antigen presenting glycoprotein homologous to MHC I; however, CD1 proteins present lipid rather than peptide antigen. CD1 proteins are well established to present lipid antigens ofMycobacterium tuberculosis(Mtb) to T cells, but understandin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33723b898eecca120ee23cca2f83b3e3
https://doi.org/10.1101/2023.05.23.541963
https://doi.org/10.1101/2023.05.23.541963