Zobrazeno 1 - 10
of 237
pro vyhledávání: '"K, Pickrell"'
Autor:
Justin W. Buchanan, Lex E. Flagel, Michael D. MacNeil, Ashley R. Nilles, Jesse L. Hoff, Joseph K. Pickrell, Randall C. Raymond
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
The increasing incidence of bovine congestive heart failure (BCHF) in feedlot cattle poses a significant challenge to the beef industry from economic loss, reduced performance, and reduced animal welfare attributed to cardiac insufficiency. Changes t
Externí odkaz:
https://doaj.org/article/b2b345f4a20f483bb4a436760ebd3fee
Autor:
Kaja Wasik, Tomaz Berisa, Joseph K. Pickrell, Jeremiah H. Li, Dana J. Fraser, Karen King, Charles Cox
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-7 (2021)
Abstract Background Low pass sequencing has been proposed as a cost-effective alternative to genotyping arrays to identify genetic variants that influence multifactorial traits in humans. For common diseases this typically has required both large sam
Externí odkaz:
https://doaj.org/article/43f26d9f2e1b443fa4b8b71ea76a7c78
Autor:
Sarah Kim-Hellmuth, Matthias Bechheim, Benno Pütz, Pejman Mohammadi, Yohann Nédélec, Nicholas Giangreco, Jessica Becker, Vera Kaiser, Nadine Fricker, Esther Beier, Peter Boor, Stephane E. Castel, Markus M. Nöthen, Luis B. Barreiro, Joseph K. Pickrell, Bertram Müller-Myhsok, Tuuli Lappalainen, Johannes Schumacher, Veit Hornung
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Insight into the genetic influence on the immune response is important for the understanding of interindividual variability in human pathologies. Here, the authors generate transcriptome data from human blood monocytes stimulated with various immune
Externí odkaz:
https://doaj.org/article/f274c977e16349e182f563f89ede2112
Autor:
Jeremiah H. Li, Karrah Findley, Joseph K. Pickrell, Kelly Blease, Junhua Zhao, Semyon Kruglyak
Low-pass sequencing with genotype imputation has been adopted as a cost-effective method for genotyping. The most widely used method of short-read sequencing uses sequencing by synthesis (SBS). Here we perform a study of a novel sequencing technology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9afff9a7723b38d675cfd73263388bc0
https://doi.org/10.1101/2022.12.07.519512
https://doi.org/10.1101/2022.12.07.519512
Autor:
Hakhamanesh Mostafavi, Tomaz Berisa, Felix R Day, John R B Perry, Molly Przeworski, Joseph K Pickrell
Publikováno v:
PLoS Biology, Vol 15, Iss 9, p e2002458 (2017)
A number of open questions in human evolutionary genetics would become tractable if we were able to directly measure evolutionary fitness. As a step towards this goal, we developed a method to examine whether individual genetic variants, or sets of g
Externí odkaz:
https://doaj.org/article/1058f9c026d74d709d5d086803e46b72
Publikováno v:
Genome Res
Low-pass sequencing (sequencing a genome to an average depth less than 1x coverage) combined with genotype imputation has been proposed as an alternative to genotyping arrays for trait mapping and calculation of polygenic scores; however, the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fede88cf9159f43ae7b983b370fd6b
https://doi.org/10.1101/gr.266486.120
https://doi.org/10.1101/gr.266486.120
Autor:
NeuroGAP-Psychosis Study Team, Roxanne James, Carter P. Newman, Rocky E. Stroud, Abebaw Fekadu, Joseph Kyebuzibwa, Sheila Dodge, Elizabeth G. Atkinson, Lerato Majara, Dan J. Stein, Zukiswa Zingela, Wilfred E. Injera, Lori B. Chibnik, Mark J. Daly, Raj Ramesar, Karestan C. Koenen, Anne Stevenson, Tamrat Abebe, Solomon Teferra, Gabriel Kigen, Timothy DeSmet, Symon M. Kariuki, Joseph K. Pickrell, Stella Gichuru, Melkam Alemayehu, Fred K. Ashaba, Welelta Shiferaw, Lukoye Atwoli, Dickens Akena, Edith Kwobah, Charles R. Newton, Tera Bowers, Steven Ferriera, Rehema M. Mwema, Benjamin M. Neale, Bizu Gelaye, Alicia R. Martin, Henry Musinguzi, Celia van der Merwe, Sinéad B. Chapman
Publikováno v:
Am J Hum Genet
BackgroundGenetic studies of biomedical phenotypes in underrepresented populations identify disproportionate numbers of novel associations. However, current genomics infrastructure--including most genotyping arrays and sequenced reference panels--bes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333c6c8cce23eb2d2e8cd884f6b1d7cd
https://pubmed.ncbi.nlm.nih.gov/33770507
https://pubmed.ncbi.nlm.nih.gov/33770507
Autor:
Daphna Weissglas-Volkov, Regev Schweiger, Joseph K. Pickrell, Jeremiah H. Li, Ella Petter, Tal Shor, Lior Almog, Tomaz Berisa, Yoav Naveh, Bar Shahino, Malka Aker, Yaniv Erlich, Shai Carmi, Oron Navon
Finding familial relatives using DNA has multiple applications, in genetic genealogy, population genetics, and forensics. So far, most relative matching algorithms rely on detecting identity-by-descent (IBD) segments with high quality genotype data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e910b15b95823e68bada7c8e641db5
https://doi.org/10.1101/2020.09.09.289322
https://doi.org/10.1101/2020.09.09.289322
Autor:
Luke A. Morris, Peter Andolfatto, Luke Sarre, Mikhail V. Matz, Joseph K. Pickrell, Neal E. Cantin, Yi Liao, Molly Przeworski, Zachary L. Fuller, Julie Peng, Line K. Bay, Jihanne Shepherd, Veronique J. L. Mocellin
Publikováno v:
Science. 369
Conservation help from genomics Corals worldwide are under threat from rising sea temperatures and pollution. One response to heat stress is coral bleaching—the loss of photosynthetic endosymbionts that provide energy for the coral. Fuller et al. p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3750a9b7fc5e7638c36cb1a2dd14b07
https://doi.org/10.1126/science.aba4674
https://doi.org/10.1126/science.aba4674
Autor:
Jean-Baptiste Veyrieras, Daniel J Gaffney, Joseph K Pickrell, Yoav Gilad, Matthew Stephens, Jonathan K Pritchard
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30629 (2012)
Mapping of expression quantitative trait loci (eQTLs) is an important technique for studying how genetic variation affects gene regulation in natural populations. In a previous study using Illumina expression data from human lymphoblastoid cell lines
Externí odkaz:
https://doaj.org/article/d400baa427bf478d840b8ba754701f57