Zobrazeno 1 - 10
of 136
pro vyhledávání: '"K, Penttilä"'
Autor:
Sami Qadri, Emilia Vartiainen, Mari Lahelma, Kimmo Porthan, An Tang, Ilkay S. Idilman, Jurgen H. Runge, Anne Juuti, Anne K. Penttilä, Juhani Dabek, Tiina E. Lehtimäki, Wenla Seppänen, Johanna Arola, Perttu Arkkila, Jaap Stoker, Musturay Karcaaltincaba, Michael Pavlides, Rohit Loomba, Claude B. Sirlin, Taru Tukiainen, Hannele Yki-Järvinen
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100928- (2024)
Background & Aims: Pathologists quantify liver steatosis as the fraction of lipid droplet-containing hepatocytes out of all hepatocytes, whereas the magnetic resonance-determined proton density fat fraction (PDFF) reflects the tissue triacylglycerol
Externí odkaz:
https://doaj.org/article/a39650dc9d9c4a118292df1177d010ab
Autor:
Ina Luiken, Stephan Eisenmann, Jakob Garbe, Hanna Sternby, Robert C Verdonk, Alexandra Dimova, Povilas Ignatavicius, Lucas Ilzarbe, Peeter Koiva, Anne K Penttilä, Sara Regnér, Johannes Dober, Walter A Wohlgemuth, Richard Brill, Patrick Michl, Jonas Rosendahl, Marko Damm
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263739 (2022)
BackgroundRespiratory failure worsens the outcome of acute pancreatitis (AP) and underlying factors might be early detectable.AimsTo evaluate the prevalence and prognostic relevance of early pleuropulmonary pathologies and pre-existing chronic lung d
Externí odkaz:
https://doaj.org/article/a959f93345254965a7d635aed1d47a41
Autor:
Panu K. Luukkonen, Ikki Sakuma, Rafael C. Gaspar, Meghan Mooring, Ali Nasiri, Mario Kahn, Xian-Man Zhang, Dongyan Zhang, Henna Sammalkorpi, Anne K. Penttilä, Marju Orho-Melander, Johanna Arola, Anne Juuti, Xuchen Zhang, Dean Yimlamai, Hannele Yki-Järvinen, Kitt Falk Petersen, Gerald I. Shulman
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, in which prognosis is determined by liver fibrosis. A common variant in hydroxysteroid 17-beta dehydrogenase 13 ( HSD17B13 , rs72613567-A) is associated with a reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e00c6a62d24933271105d69ddf57a566
https://doi.org/10.1073/pnas.2217543120
https://doi.org/10.1073/pnas.2217543120
Autor:
Sami Qadri, Noora Ahlholm, Ida Lønsmann, Paola Pellegrini, Anni Poikola, Panu K Luukkonen, Kimmo Porthan, Anne Juuti, Henna Sammalkorpi, Anne K Penttilä, Roberta D’Ambrosio, Giorgio Soardo, Diana J Leeming, Morten Karsdal, Johanna Arola, Stergios Kechagias, Serena Pelusi, Mattias Ekstedt, Luca Valenti, Hannes Hagström, Hannele Yki-Järvinen
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:e2008-e2020
Context Guidelines recommend blood-based fibrosis biomarkers to identify advanced nonalcoholic fatty liver disease (NAFLD), which is particularly prevalent in patients with obesity. Objective To study whether the degree of obesity affects the perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04738b7aebc1de640e4d88e4544005a6
https://doi.org/10.1210/clinem/dgab933
https://doi.org/10.1210/clinem/dgab933
Autor:
Anne K. Penttilä, Outi Lindström, Johanna Hästbacka, Krista Kuuliala, Harri Mustonen, Pauli Puolakkainen, Antti Kuuliala, Marko Salmi, Mari Hämäläinen, Eeva Moilanen, Heikki Repo, Leena Kylänpää
Publikováno v:
Cogent Medicine, Vol 4, Iss 1 (2017)
Objectives: We aimed to study if interleukin (IL) 8 and hepatocyte growth factor (HGF) predict development of severe acute pancreatitis (SAP) among patients without organ dysfunction (OD) at presentation, and if they discriminate transient OD from pe
Externí odkaz:
https://doaj.org/article/5074256e57b446b8be096906dc67d501
Autor:
Kimmo Porthan, Hannele Yki-Järvinen, Marju Orho-Melander, Panu K. Luukkonen, Sami Qadri, Anne K. Penttilä, Amalia Gastaldelli, Jussi Pihlajamäki, Henna Sammalkorpi, Anne Juuti, Ville Männistö, Melania Gaggini, Johanna Arola, A. Hakkarainen, Mika Ala-Korpela, Noora Ahlholm, Leanne Hodson, Tiina Lehtimäki
Funding Information: This study was supported by Academy of Finland Grant 309263 (H.Y.-J.) and Grant 138006 (J.P.), EU H2020 project ?Elucidating Pathways of Steatohepatitis? EPoS Grant 634413 (H.Y.-J.), H2020-JTI-IMI2 EU project 777377-2 Liver Inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b1234c3153825c13c260807f3846a9
https://aaltodoc.aalto.fi/handle/123456789/113033
https://aaltodoc.aalto.fi/handle/123456789/113033
Pleuropulmonary pathologies in the early phase of acute pancreatitis correlate with disease severity
Autor:
Jakob Garbe, P. Koiva, Hanna Sternby, L. Ilzarbe, Richard Brill, A. Dimova, Stephan Eisenmann, Jonas Rosendahl, I Luiken, J Dober, Povilas Ignatavicius, Walter A. Wohlgemuth, Anne K. Penttilä, Marko Damm, Sara Regnér, Patrick Michl, R.C. Verdonk
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 2, p e0263739 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263739 (2022)
BackgroundRespiratory failure worsens the outcome of acute pancreatitis (AP) and underlying factors might be early detectable.AimsTo evaluate the prevalence and prognostic relevance of early pleuropulmonary pathologies and pre-existing chronic lung d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a990bb69dc249c01c9cbc05b3009c194
http://hdl.handle.net/10230/54441
http://hdl.handle.net/10230/54441
Autor:
Anne K. Penttilä, Henna Sammalkorpi, Toni Ihalainen, Kirsi H. Pietiläinen, Antti Loimaala, Anne Juuti, Tuure Saarinen
Publikováno v:
Obesity Surgery
Introduction Data on postoperative bile reflux after one anastomosis gastric bypass (OAGB) is lacking. Bile reflux scintigraphy (BRS) has been shown to be a reliable non-invasive tool to assess bile reflux after OAGB. We set out to study bile reflux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3e1319c3a4bc5bdb78d24b43be631d
http://europepmc.org/articles/PMC7347680
http://europepmc.org/articles/PMC7347680
Autor:
Panu K. Luukkonen, Anne Juuti, Marju Orho-Melander, Anne K. Penttilä, Sami Qadri, Henna Sammalkorpi, Tiina Lehtimäki, Johanna Arola, Hannele Yki-Järvinen, Antti Hakkarainen
Context The I148M (rs738409-G) variant in PNPLA3 increases liver fat content but may be protective against cardiovascular disease. Insulin resistance (IR) amplifies the effect of PNPLA3-I148M on liver fat. Objective To study whether PNPLA3-I148M conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010369d66edab83b3a1ffaa642b0ea5c
http://hdl.handle.net/10138/338159
http://hdl.handle.net/10138/338159
Autor:
Henna Sammalkorpi, Matej Orešič, Vesa M. Olkkonen, Julia Perttilä, Panu K. Luukkonen, Marju Orho-Melander, Leanne Hodson, Sami Qadri, Antti Hakkarainen, Anne K. Penttilä, Hannele Yki-Järvinen, Tuulia Hyötyläinen, Tiina Lehtimäki, Susanna Lallukka-Brück, Amalia Gastaldelli, Anne Juuti, You Zhou
Background & Aims\ud \ud The I148M variant in PNPLA3 is the major genetic risk factor for non‐alcoholic fatty liver disease (NAFLD). The liver is enriched with polyunsaturated triglycerides (PUFA‐TGs) in PNPLA3‐I148M carriers. Gene expression d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006cf53338d91034077f861f90ec8683
http://hdl.handle.net/10138/333732
http://hdl.handle.net/10138/333732