Naturally-occurring serotype 3 Streptococcus pneumoniae strains that lack functional pneumolysin and autolysin have attenuated virulence but induce localized protective immune responses.

Autor: Ηαnnah E Wong, Panagiotis Tourlomousis, Gavin K Paterson, Steve Webster, Clare E Bryant

Publikováno v: PLoS ONE, Vol 18, Iss 3, p e0282843 (2023)

Streptococcus pneumoniae is an important cause of fatal pneumonia in humans. These bacteria express virulence factors, such as the toxins pneumolysin and autolysin, that drive host inflammatory responses. In this study we confirm loss of pneumolysin

Externí odkaz: https://doaj.org/article/d077cbcb7aed406297989b789ccce70e

Prevalence and characterisation of methicillin-resistant staphylococci from bovine bulk tank milk in England and Wales

Autor: Elizabeth A. Fisher, Gavin K Paterson

Publikováno v: Journal of Global Antimicrobial Resistance, Vol 22, Iss , Pp 139-144 (2020)

Objectives: To investigate the prevalence and characteristics of methicillin-resistant staphylococci on dairy farms in England and Wales including zoonotic MRSA. Methods: Bulk tank milk was sampled from 363 dairy farms in 2015-2016 and methicillin-re

Externí odkaz: https://doaj.org/article/20c4f23e80784004886878eada377581

Erratum to: Measurement of $$\psi (2S)$$ ψ(2S) meson production in pp collisions at $$\sqrt{s}=7\,\hbox {TeV}$$ s=7TeV

Autor: R. Aaij, C. Abellán Beteta, B. Adeva, M. Adinolfi, C. Adrover, A. Affolder, Z. Ajaltouni, J. Albrecht, F. Alessio, M. Alexander, G. Alkhazov, P. Alvarez Cartelle, A. A. Alves Jr, S. Amato, Y. Amhis, J. Anderson, F. Andrianala, R. B. Appleby, F. Archilli, L. Arrabito, A. Artamonov, M. Artuso, E. Aslanides, G. Auriemma, S. Bachmann, J. J. Back, D. S. Bailey, V. Balagura, W. Baldini, R. J. Barlow, C. Barschel, S. Barsuk, W. Barter, A. Bates, Th. Bauer, A. Bay, I. Bediaga, S. Belogurov, K. Belous, I. Belyaev, E. Ben-Haim, M. Benayoun, G. Bencivenni, S. Benson, J. Benton, R. Bernet, M. O. Bettler, M. van Beuzekom, A. Bien, S. Bifani, A. Bizzeti, P. M. Bjørnstad, T. Blake, F. Blanc, C. Blanks, J. Blouw, S. Blusk, A. Bobrov, V. Bocci, A. Bondar, N. Bondar, W. Bonivento, S. Borghi, A. Borgia, T. J. V. Bowcock, C. Bozzi, T. Brambach, J. van den Brand, J. Bressieux, D. Brett, M. Britsch, T. Britton, N. H. Brook, H. Brown, A. Bursche, J. Buytaert, A. Büchler-Germann, S. Cadeddu, O. Callot, M. Calvi, M. Calvo Gomez, A. Camboni, P. Campana, A. Carbone, G. Carboni, R. Cardinale, A. Cardini, L. Carson, K. Carvalho Akiba, G. Casse, M. Cattaneo, Ch. Cauet, M. Charles, Ph. Charpentier, N. Chiapolini, M. Chrzaszcz, P. Ciambrone, K. Ciba, X. Cid Vidal, G. Ciezarek, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, C. Coca, V. Coco, J. Cogan, P. Collins, A. Comerma-Montells, F. Constantin, A. Cook, M. Coombes, G. Corti, B. Couturier, G. A. Cowan, R. Currie, C. D’Ambrosio, P. David, P. N. Y. David, O. De Aguiar Francisco, K. De Bruyn, M. De Cian, F. De Lorenzi, J. M. De Miranda, L. De Paula, P. De Simone, D. Decamp, M. Deckenhoff, H. Degaudenzi, L. Del Buono, C. Deplano, D. Derkach, O. Deschamps, F. Dettori, J. Dickens, H. Dijkstra, P. Diniz Batista, F. Domingo Bonal, S. Donleavy, F. Dordei, A. Dosil Suárez, D. Dossett, A. Dovbnya, F. Dupertuis, R. Dzhelyadin, A. Dziurda, S. Easo, U. Egede, V. Egorychev, S. Eidelman, D. van Eijk, F. Eisele, S. Eisenhardt, R. Ekelhof, L. Eklund, Ch. Elsasser, D. Elsby, D. Esperante Pereira, A. Falabella, E. Fanchini, G. Fardell, C. Farinelli, S. Farry, V. Fave, V. Fernandez Albor, F. Ferreira Rodrigues, M. Ferro-Luzzi, S. Filippov, C. Fitzpatrick, M. Fontana, F. Fontanelli, R. Forty, M. Frank, C. Frei, M. Frosini, S. Furcas, C. Färber, A. Gallas Torreira, D. Galli, M. Gandelman, P. Gandini, Y. Gao, J-C. Garnier, J. Garofoli, J. Garra Tico, L. Garrido, D. Gascon, C. Gaspar, R. Gauld, N. Gauvin, M. Gersabeck, T. Gershon, Ph. Ghez, V. Gibson, V. V. Gligorov, D. Golubkov, A. Golutvin, A. Gomes, H. Gordon, C. Gotti, M. Grabalosa Gándara, R. Graciani Diaz, L. A. Granado Cardoso, E. Graugés, G. Graziani, A. Grecu, E. Greening, S. Gregson, B. Gui, E. Gushchin, Yu. Guz, T. Gys, C. Göbel, C. Hadjivasiliou, G. Haefeli, C. Haen, S. C. Haines, T. Hampson, S. Hansmann-Menzemer, R. Harji, N. Harnew, J. Harrison, P. F. Harrison, T. Hartmann, J. He, V. Heijne, K. Hennessy, P. Henrard, J. A. Hernando Morata, E. van Herwijnen, E. Hicks, K. Holubyev, W. Hulsbergen, P. Hunt, T. Huse, R. S. Huston, D. Hutchcroft, D. Hynds, V. Iakovenko, P. Ilten, J. Imong, A. Inyakin, R. Jacobsson, A. Jaeger, M. Jahjah Hussein, E. Jans, F. Jansen, P. Jaton, B. Jean-Marie, F. Jing, M. John, D. Johnson, C. R. Jones, B. Jost, S. Kandybei, M. Karacson, T. M. Karbach, J. Keaveney, I. R. Kenyon, U. Kerzel, T. Ketel, A. Keune, B. Khanji, Y. M. Kim, M. Knecht, R. F. Koopman, P. Koppenburg, A. Kozlinskiy, L. Kravchuk, K. Kreplin, M. Kreps, G. Krocker, P. Krokovny, F. Kruse, K. Kruzelecki, M. Kucharczyk, T. Kvaratskheliya, V. N. La Thi, D. Lacarrere, G. Lafferty, A. Lai, D. Lambert, R. W. Lambert, E. Lanciotti, G. Lanfranchi, C. Langenbruch, T. Latham, C. Lazzeroni, R. Le Gac, J. van Leerdam, J.-P. Lees, A. Leflat, J. Lefrançois, R. Lefèvre, O. Leroy, T. Lesiak, L. Li, P.-R. Li, L. Li Gioi, M. Lieng, M. Liles, R. Lindner, C. Linn, B. Liu, G. Liu, J. von Loeben, J. H. Lopes, E. Lopez Asamar, N. Lopez-March, H. Lu, J. Luisier, X.-R. Lyu, A. Mac Raighne, F. Machefert, F. Maciuc, O. Maev, S. Malde, R. M. D. Mamunur, G. Manca, G. Mancinelli, N. Mangiafave, J. F. Marchand, U. Marconi, J. Marks, G. Martellotti, A. Martens, L. Martin, D. Martinez Santos, A. Martín Sánchez, A. Massafferri, Z. Mathe, C. Matteuzzi, M. Matveev, E. Maurice, B. Maynard, A. Mazurov, G. McGregor, R. McNulty, M. Meissner, M. Merk, J. Merkel, R. Messi, S. Miglioranzi, D. A. Milanes, M.-N. Minard, J. Molina Rodriguez, S. Monteil, D. Moran, P. Morawski, R. Mountain, I. Mous, F. Muheim, R. Muresan, B. Muster, M. Musy, J. Mylroie-Smith, R. Märki, K. Müller, P. Naik, T. Nakada, R. Nandakumar, I. Nasteva, M. Nedos, M. Needham, N. Neufeld, A. D. Nguyen, C. Nguyen-Mau, M. Nicol, V. Niess, N. Nikitin, T. Nikodem, A. Nomerotski, A. Novoselov, A. Oblakowska-Mucha, V. Obraztsov, S. Oggero, S. Ogilvy, R. Oldeman, J. M. Otalora Goicochea, P. Owen, B. K. Pal, J. Palacios, A. Palano, M. Palutan, J. Panman, A. Papanestis, M. Pappagallo, C. Parkes, C. J. Parkinson, G. Passaleva, G. D. Patel, M. Patel, S. K. Paterson, G. N. Patrick, C. Patrignani, A. Pellegrino, G. Penso, M. Pepe Altarelli, S. Perazzini, D. L. Perego, P. Perret, M. Perrin-Terrin, A. Petrella, A. Petrolini, A. Phan, E. Picatoste Olloqui, B. Pie Valls, B. Pietrzyk, T. Pilař, D. Pinci, R. Plackett, S. Playfer, M. Plo Casasus, G. Polok, A. Poluektov, I. Polyakov, E. Polycarpo, D. Popov, B. Popovici, C. Potterat, A. Powell, J. Prisciandaro, V. Pugatch, A. Puig Navarro, A. Pérez-Calero Yzquierdo, W. Qian, J. H. Rademacker, B. Rakotomiaramanana, M. S. Rangel, I. Raniuk, G. Raven, S. Redford, M. M. Reid, A. C. dos Reis, S. Ricciardi, A. Richards, K. Rinnert, D. A. Roa Romero, P. Robbe, E. Rodrigues, P. Rodriguez Perez, G. J. Rogers, S. Roiser, V. Romanovskiy, J. Rouvinet, T. Ruf, H. Ruiz, G. Sabatino, J. J. Saborido Silva, N. Sagidova, P. Sail, B. Saitta, C. Salzmann, M. Sannino, R. Santacesaria, C. Santamarina Rios, R. Santinelli, E. Santovetti, M. Sapunov, A. Sarti, C. Satriano, A. Satta, M. Saur, D. Savrina, P. Schaack, M. Schiller, S. Schleich, M. Schlupp, M. Schmelling, B. Schmidt, O. Schneider, A. Schopper, M. H. Schune, R. Schwemmer, B. Sciascia, A. Sciubba, A. Semennikov, K. Senderowska, I. Sepp, N. Serra, J. Serrano, P. Seyfert, M. Shapkin, Y. Shcheglov, T. Shears, L. Shekhtman, V. Shevchenko, A. Shires, R. Silva Coutinho, T. Skwarnicki, E. Smith, K. Sobczak, F. J. P. Soler, A. Solomin, F. Soomro, B. Souza De Paula, B. Spaan, A. Sparkes, P. Spradlin, F. Stagni, S. Stahl, O. Steinkamp, O. Stenyakin, S. Stoica, S. Stone, B. Storaci, M. Straticiuc, U. Straumann, V. K. Subbiah, S. Swientek, M. Szczekowski, P. Szczypka, T. Szumlak, S. T’Jampens, E. Teodorescu, F. Teubert, E. Thomas, J. van Tilburg, V. Tisserand, M. Tobin, N. Torr, E. Tournefier, S. Tourneur, M. T. Tran, A. Tsaregorodtsev, N. Tuning, M. Ubeda Garcia, A. Ukleja, P. Urquijo, U. Uwer, V. Vagnoni, G. Valenti, R. Vazquez Gomez, P. Vazquez Regueiro, S. Vecchi, J. J. Velthuis, M. Veltri, B. Viaud, I. Videau, D. Vieira, X. Vilasis-Cardona, J. Visniakov, A. Vollhardt, D. Volyanskyy, D. Voong, A. Vorobyev, S. Wandernoth, J. Wang, D. R. Ward, N. K. Watson, A. D. Webber, D. Websdale, M. Whitehead, D. Wiedner, L. Wiggers, G. Wilkinson, M. P. Williams, M. Williams, F. F. Wilson, J. Wishahi, M. Witek, W. Witzeling, S. A. Wotton, K. Wyllie, Y. Xie, Z. Xing, Z. Yang, R. Young, O. Yushchenko, M. Zangoli, M. Zavertyaev, F. Zhang, L. Zhang, W. C. Zhang, Y. Zhang, A. Zhelezov, A. Zhokhov, L. Zhong, A. Zvyagin, LHCb Collaboration

Publikováno v: European Physical Journal C: Particles and Fields, Vol 80, Iss 1, Pp 1-7 (2020)

This erratum corrects measurements of the prompt and secondary (from-b).

Externí odkaz: https://doaj.org/article/bf0bdf6cc7434610bf2b8d2b65a654f8

Evolutionary and Functional Analysis of Coagulase Positivity among the Staphylococci

Autor: Amy C. Pickering, Gonzalo Yebra, Xiangyu Gong, Mariya I. Goncheva, Bryan A. Wee, Alison C. MacFadyen, Lukas F. Muehlbauer, Joana Alves, Robyn A. Cartwright, Gavin K. Paterson, J. Ross Fitzgerald

Publikováno v: mSphere, Vol 6, Iss 4 (2021)

The ability of some species of staphylococci to promote coagulation of plasma is a key pathogenic and diagnostic trait. Here, we provide a comprehensive analysis of the coagulase positivity of the staphylococci and its evolutionary genetic basis.

Externí odkaz: https://doaj.org/article/75b2f1900dc14e7b891b4aec14c983fc

ASPIRE-3-PREVENT: a cross-sectional survey of preventive care after a coronary event across the UK

Autor: Paul Bassett, Catriona S Jennings, J Shah, A Sutherland, N Singh, M Mohan, D Wood, K Orr, S Clark, C Morgan, A Taylor, C Gale, M Cunningham, A Nicholson, J Wright, C Edwards, J Harrison, K Lyons, C Mills, M Baker, N Hussain, J Porter, A Hunt, David Wood, Kornelia Kotseva, Agnieszka Adamska, A Adamska, S Adamska, C Jennings, K Kotseva, A Hoye, P Atkin, D Fellowes, A Negahban, A Daniels, L Zeidan, S Iyer, M Ocampo, A Sevillano, G Galasko, L Benham, S Preston, D Sebastian, S Lindsay, C Atkinson, C Kranilla, M Vinod, H Abbass, N Rhoualmi, Y Beerachee, C Bennett, M Broome, A Bwalya, Lindsay Caygill, L Dinning, A Gillespie, R Goodfellow, J Guy, T Idress, N Oustance, M Yare, J M Jagoda, H Bowyer, V Christenssen, A Groves, P I Jan, A Riaz, M Gill, T A Sewell, D Gorog, P De Sousa, T Mazenenga, A Banfield, R Encarnado, C Travill, S Gent, F Haines, T Peachey, J Taaffe, K Wells, D P Ripley, H Forward, H McKie, SL Pick, H E Thomas, P D Batin, D Exley, T Rank, A Kardos, S-B Sutherland, L Wren, P Leeson, D Barker, B Moreby, J Sawyer, J Sobolewska, D Adams, C Corbett, K Hallett, S Kaye, L Morby, L Winstanley, J Stirrup, M Brunton, M M Gandhi, L Adams, L Tapp, V Ansell, S Hyndman, A Brodison, J Craig, S Peters, R Kaprielian, A Bucaj, K Mahay, M Oblak, A Sultan, K Duell, M Gaskell, L Heaton, C Moore, V Parkinson, T Taylor, C Tierney, K Vandesnepscheut-Jones, A Broadley, C Buckley, L Matthews, L Pippard, M Pye, Y McGill, H Redfearn, M Fearnley, L Miskelly, S O Mullan, M Spencer, E McCart, P Donnelly, S Kelly, S Regan, D Turnbull, Dana Dawson, B Brikinns, K Oldroyd, F Teyhan, J Kelly, A Tewkesbury, D Newby, K Combe, L Derr, J Donnelly, L Flint, A Gill, M Glenwright, H Nailon, E McDonald, C Mahoney, F Morrow, K Paterson, B Poulose, B Rif, N Spath, H Spence, J Watt, C Barr, S Dekker, D McDonald, L O'Keeffe, I Shread, C C Lang, AM Choy, L Douglas, S Kalra, R Symon, J Halcox, K Baldwin, H Goldring, C Thomas, L Izzat, D Evans, Z Omar, E Perkins

Publikováno v: Open Heart, Vol 7, Iss 1 (2020)

Objective To quantify the implementation of the third Joint British Societies’ Consensus Recommendations for the Prevention of Cardiovascular Disease (JBS3) after coronary event.Methods Using a cross-sectional survey design, patients were consecuti

Externí odkaz: https://doaj.org/article/675df7969897467bbf6ded61409265b7