In-depth analysis of the long-term processability of materials during continuous feeding

Autor: B, Bekaert, B, Van Snick, K, Pandelaere, J, Dhondt, G, Di Pretoro, T, De Beer, C, Vervaet, V, Vanhoorne

Publikováno v: INTERNATIONAL JOURNAL OF PHARMACEUTICS

This study determined the feasibility of long-term continuous powder feeding and its effect on the overall process performance. Additionally, quantitative relationships were established between material properties, process settings and screw feeding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ec01ba8b7c477350e87497693a5f5a
https://doi.org/10.1016/j.ijpharm.2022.121454

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Continuous direct compression: Development of an empirical predictive model and challenges regarding PAT implementation.

Autor: Bekaert B; Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium., Van Snick B; Oral Solid Dosage, Drug Product Development, Discovery Product Development and Supplies, Pharmaceutical Research and Development, Division of Janssen Pharmaceutica, Johnson & Johnson, Turnhoutseweg 30, B-2340 Beerse, Belgium., Pandelaere K; Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium., Dhondt J; Oral Solid Dosage, Drug Product Development, Discovery Product Development and Supplies, Pharmaceutical Research and Development, Division of Janssen Pharmaceutica, Johnson & Johnson, Turnhoutseweg 30, B-2340 Beerse, Belgium., Di Pretoro G; Oral Solid Dosage, Drug Product Development, Discovery Product Development and Supplies, Pharmaceutical Research and Development, Division of Janssen Pharmaceutica, Johnson & Johnson, Turnhoutseweg 30, B-2340 Beerse, Belgium., De Beer T; Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutical Analysis, Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium., Vervaet C; Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium., Vanhoorne V; Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium.

Publikováno v: International journal of pharmaceutics: X [Int J Pharm X] 2021 Dec 25; Vol. 4, pp. 100110. Date of Electronic Publication: 2021 Dec 25 (Print Publication: 2022).