Zobrazeno 1 - 10
of 10 695
pro vyhledávání: '"K, Martin"'
Autor:
Florence M. Chardon, Troy A. McDiarmid, Nicholas F. Page, Riza M. Daza, Beth K. Martin, Silvia Domcke, Samuel G. Regalado, Jean-Benoît Lalanne, Diego Calderon, Xiaoyi Li, Lea M. Starita, Stephan J. Sanders, Nadav Ahituv, Jay Shendure
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract CRISPR-based gene activation (CRISPRa) is a strategy for upregulating gene expression by targeting promoters or enhancers in a tissue/cell-type specific manner. Here, we describe an experimental framework that combines highly multiplexed per
Externí odkaz:
https://doaj.org/article/9bd7fc937a4c4d249a6334bbcbf59eb9
Autor:
David F. Read, Gregory T. Booth, Riza M. Daza, Dana L. Jackson, Rula Green Gladden, Sanjay R. Srivatsan, Brent Ewing, Jennifer M. Franks, Cailyn H. Spurrell, Anne Roshella Gomes, Diana O’Day, Aishwarya A. Gogate, Beth K. Martin, Haleigh Larson, Christian Pfleger, Lea Starita, Yiing Lin, Jay Shendure, Shin Lin, Cole Trapnell
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Sex differences and age-related changes in the human heart at the tissue, cell, and molecular level have been well-documented and many may be relevant for cardiovascular disease. However, how molecular programs within individual cell types v
Externí odkaz:
https://doaj.org/article/c78d59de759c46328c8bc8b520ab680e
Autor:
Nicholas R. Kurtansky, Brian M. D’Alessandro, Maura C. Gillis, Brigid Betz-Stablein, Sara E. Cerminara, Rafael Garcia, Marcela Alves Girundi, Elisabeth Victoria Goessinger, Philippe Gottfrois, Pascale Guitera, Allan C. Halpern, Valerie Jakrot, Harald Kittler, Kivanc Kose, Konstantinos Liopyris, Josep Malvehy, Victoria J. Mar, Linda K. Martin, Thomas Mathew, Lara Valeska Maul, Adam Mothershaw, Alina M. Mueller, Christoph Mueller, Alexander A. Navarini, Tarlia Rajeswaran, Vin Rajeswaran, Anup Saha, Maithili Sashindranath, Laura Serra-García, H. Peter Soyer, Georgios Theocharis, Ayesha Vos, Jochen Weber, Veronica Rotemberg
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-11 (2024)
Abstract AI image classification algorithms have shown promising results when applied to skin cancer detection. Most public skin cancer image datasets are comprised of dermoscopic photos and are limited by selection bias, lack of standardization, and
Externí odkaz:
https://doaj.org/article/5622b491e13d4ffc9f4616a4f3f518b9
Autor:
Wang, Mingyuan, Tan, Mingsheng, Shi, Yuejiang, Wang, Ziqi, Dong, Jiaqi, Liu, Adi, Zhuang, Ge, Li, Songjian, Song, Shaodong, Yuan, Baoshan, Peng, Y-K Martin
In this study, the first observation of high-frequency instabilities driven by runaway electrons has been reported in the EXL-50 spherical torus using a high-frequency magnetic pickup coil. The central frequency of these instabilities is found to be
Externí odkaz:
http://arxiv.org/abs/2307.06498
Autor:
Wang, Mingyuan, Shi, Yuejiang, Dong, Jiaqi, Gao, Xinliang, Lu, Quanming, Wang, Ziqi, Chen, Wei, Liu, Adi, Zhang, Ge, Wang, Yumin, Cheng, Shikui, Tan, Mingsheng, Li, Songjian, Song, Shaodong, Sun, Tiantian, Liu, Bing, Huang, Xianli, Li, Yingying, Song, Xianming, Yuan, Baoshan, Peng, Y-K Martin, team, ENN
Electromagnetic modes in the frequency range of 30-120MHz were observed in electron cyclotron wave (ECW) steady state plasmas on the ENN XuanLong-50 (EXL-50) spherical torus. These modes were found to have multiple bands of frequencies proportional t
Externí odkaz:
http://arxiv.org/abs/2307.06497
Autor:
Qiao, G. J., Luo, D., Song, S. D., Dong, J. Q., Shi, Y. J., Li, J. C., Du, D., Peng, Y. K. Martin, Liu, M. S., team, EXL-50
Analysis of helicon wave heating and current drive capability in EXL-50 spherical torus plasmas has been conducted. It is found that the driven current increases with the launched parallel refractive index $n_{||}$ and peaks around $n_{||} = 4.0$ whe
Externí odkaz:
http://arxiv.org/abs/2212.08894
Autor:
Tamaki Suematsu, Zane K. Martin, Elizabeth A. Barnes, Charlotte A. DeMott, Samson Hagos, Yoo-Geun Ham, Daehyun Kim, Hyemi Kim, Tieh-Yong Koh, Eric D. Maloney
Publikováno v:
npj Climate and Atmospheric Science, Vol 7, Iss 1, Pp 1-3 (2024)
The Madden–Julian oscillation (MJO) is a major tropical weather system and one of the largest sources of predictability for subseasonal-to-seasonal weather forecasts. Skillful prediction of the MJO has been a highly active area of research due to i
Externí odkaz:
https://doaj.org/article/cb5b4e9575cb48a9979dc55a029a4cda
Autor:
Luigi Marino, Bin Ni, Jared S. Farrar, Joseph C. Lownik, Janina V. Pearce, Rebecca K. Martin, Francesco S. Celi
Publikováno v:
Adipocyte, Vol 13, Iss 1 (2024)
ABSTRACTA Disintegrin And Metalloproteinase domain-containing protein 10 (ADAM10), is involved in several metabolic and inflammatory pathways. We speculated that ADAM10 plays a modulatory role in adipose tissue inflammation and metabolism. To this en
Externí odkaz:
https://doaj.org/article/ca0aa1675b914de79d66fe6633e60097
Autor:
Larissa Haertle, Umair Munawar, Hipólito N. C. Hernández, Andres Arroyo‐Barea, Tobias Heckel, Isabel Cuenca, Lucia Martin, Carlotta Höschle, Nicole Müller, Cornelia Vogt, Thorsten Bischler, Paula L. delCampo, Seungbin Han, Natalia Buenache, Xiang Zhou, Florian Bassermann, Johannes Waldschmidt, Torsten Steinbrunn, Leo Rasche, Thorsten Stühmer, Joaquin Martinez‐Lopez, K. Martin Kortüm, Santiago Barrio
Publikováno v:
HemaSphere, Vol 8, Iss 7, Pp n/a-n/a (2024)
Abstract Multiple myeloma (MM) is a genetically heterogeneous disease and the management of relapses is one of the biggest clinical challenges. TP53 alterations are established high‐risk markers and are included in the current disease staging crite
Externí odkaz:
https://doaj.org/article/315cbd46c5644a63a5886179cfc26c50