Zobrazeno 1 - 10
of 162
pro vyhledávání: '"K, Linnainmaa"'
Autor:
K. Linnainmaa, Karin Mattson, K Husgafvel-Pursiainen, H Vainio, Sirkku T. Saarikoski, K Koskinen, Ari Hirvonen
Publikováno v:
JNCI Journal of the National Cancer Institute. 88:1853-1856
Background Humans vary in their ability to metabolize endogenous and exogenous compounds. Glutathione S-transferases (GSTs) and N-acetyltransferases (NATs) are enzymes involved in the detoxification of hazardous agents. The GSTM1 and GSTT1 genes exhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec635cf8550fa1741236496d58c856d
https://doi.org/10.1093/jnci/88.24.1853
https://doi.org/10.1093/jnci/88.24.1853
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(11)
We investigated apoptosis and the expression of bcl-2, mcl-1, bcl-X, and bax in histological sections from 35 malignant mesotheliomas and 21 metastatic adenocarcinomas. Moreover, the expression of bcl-2, mcl-1, bcl-X, and bax were assessed by Western
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fde91a2f62eabbbd4a14877a45375c29
https://pubmed.ncbi.nlm.nih.gov/10589765
https://pubmed.ncbi.nlm.nih.gov/10589765
Autor:
J R, Testa, M, Carbone, A, Hirvonen, K, Khalili, B, Krynska, K, Linnainmaa, F D, Pooley, P, Rizzo, V, Rusch, G H, Xiao
Publikováno v:
Cancer research. 58(20)
Exposure to the carcinogen asbestos is a major factor in the development of malignant mesothelioma. However, not all mesotheliomas are associated with asbestos exposure, and only a small minority of people exposed to asbestos develop mesothelioma. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb6f1885fc3e73c246a9ef786d56e5d7
https://pubmed.ncbi.nlm.nih.gov/9788590
https://pubmed.ncbi.nlm.nih.gov/9788590
Publikováno v:
Acta oncologica (Stockholm, Sweden). 35(4)
The present study was carried out in order to examine the radiosensitivity of malignant pleural mesothelioma cell lines. Cell kinetics, radiation-induced delay of the cell cycle and DNA ploidy of the cell lines were also determined. For comparison an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95226307d6eec2b449d27d4a74b7182b
https://pubmed.ncbi.nlm.nih.gov/8695160
https://pubmed.ncbi.nlm.nih.gov/8695160
Publikováno v:
Cancer research. 55(14)
Besides asbestos exposure, the factors that determine susceptibility to malignant mesothelioma are unknown. We evaluated the risk of GSTM1 null genotype and slow acetylation-associated NAT2 genotype for malignant mesothelioma in relation to asbestos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3669b6e1175043ef3b8fc9b7a736bc5
https://pubmed.ncbi.nlm.nih.gov/7606714
https://pubmed.ncbi.nlm.nih.gov/7606714
Autor:
L, Hagmar, A, Brøgger, I L, Hansteen, S, Heim, B, Högstedt, L, Knudsen, B, Lambert, K, Linnainmaa, F, Mitelman, I, Nordenson
Publikováno v:
Cancer research. 54(11)
Cytogenetic assays in peripheral blood lymphocytes (PBL) have been used extensively to survey the exposure of humans to genotoxic agents. The conceptual basis for this has been the hypothesis that the extent of genetic damage in PBL reflects critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdba6cf21e329cbfbad3c331219d2a15
https://pubmed.ncbi.nlm.nih.gov/8187078
https://pubmed.ncbi.nlm.nih.gov/8187078
Autor:
A, Hand, K, Pelin, M, Halme, A, Ekman, M, Mattson, M, Vallas, K, Mattson, K, Linnainmaa, K, Husgafvel-Pursiainen
Publikováno v:
Anti-cancer drugs. 4(3)
Non-small cell lung cancers (NSCLC) are often resistant to chemotherapy. Cisplatin has shown the most activity against all the histological subtypes and is now used in most combined treatment programmes. Interferon (IFN)-alpha has been shown to poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d088239c33f84335c4e30a9e118b4b29
https://pubmed.ncbi.nlm.nih.gov/8395259
https://pubmed.ncbi.nlm.nih.gov/8395259
Autor:
R A, Metcalf, J A, Welsh, W P, Bennett, M B, Seddon, T A, Lehman, K, Pelin, K, Linnainmaa, L, Tammilehto, K, Mattson, B I, Gerwin
Publikováno v:
Cancer research. 52(9)
Twenty cell lines from 17 individuals with malignant mesothelioma have been examined for p53 alterations by direct sequencing of genomic DNA, by evaluation of mRNA expression levels, and by immunocytochemical analysis of p53 protein expression in com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a21c38145a8024dd44ecdcb3a482cb81
https://pubmed.ncbi.nlm.nih.gov/1568228
https://pubmed.ncbi.nlm.nih.gov/1568228
Autor:
A, Brøgger, L, Hagmar, I L, Hansteen, S, Heim, B, Högstedt, L, Knudsen, B, Lambert, K, Linnainmaa, F, Mitelman, I, Nordenson
Publikováno v:
Cancer genetics and cytogenetics. 45(1)
To investigate whether high rates of chromosomal aberrations (CAs), sister chromatid exchange (SCE), or micronuclei(MN) in peripheral lymphocytes indicate an increased risk for subsequent cancer, a prospective cohort study of 2,969 subjects cytogenet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::739c71f8a9e29b1183cf28a914ced7e5
https://pubmed.ncbi.nlm.nih.gov/2302690
https://pubmed.ncbi.nlm.nih.gov/2302690
Autor:
Curtis C. Harris, T.K. Smith, Brenda I. Gerwin, P. Hussain, E Spillare, A. Okamoto, Edward Gabrielson, Harvey I. Pass, S. Ungar, Koichi Hagiwara, K. Linnainmaa, Karin Mattson
Publikováno v:
Lung Cancer. 15:260-261
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e223092201c3ada0f4f05b9a352804aa
https://doi.org/10.1016/0169-5002(96)81583-2
https://doi.org/10.1016/0169-5002(96)81583-2