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miR-200a-mediated suppression of non-muscle heavy chain IIb inhibits meningioma cell migration and tumor growth in vivo

Autor: Bakhos A. Tannous, Saskia M. Peerdeman, Ozlem Senol, Engelbert Knosp, Erdogan Pekcan Erkan, Grant K. Lewandrowski, Sander R. Piersma, Thang V. Pham, Irene Slavc, Nurten Saydam, Thomas Ströbel, Christian Dorfer, Tieneke B M Schaaij-Visser, Connie R. Jimenez, Okay Saydam

Publikováno v: Senol, O, Schaaij-Visser, T B M, Erkan, E P, Dorfer, C, Lewandrowski, G, Pham, T V, Piersma, S R, Peerdeman, S M, Strobel, T, Tannous, B, Saydam, N, Slavc, I, Knosp, E, Jimenez, C R & Saydam, O 2015, ' miR-200a-mediated suppression of non-muscle heavy chain IIb inhibits meningioma cell migration and tumor growth in vivo ', Oncogene, vol. 34, no. 14, pp. 1790-1798 . https://doi.org/10.1038/onc.2014.120
Oncogene, 34(14), 1790-1798. Nature Publishing Group

miR-200a has been implicated in the pathogenesis of meningiomas, one of the most common central nervous system tumors in humans. To identify how miR-200a contributes to meningioma pathogenesis at the molecular level, we used a comparative protein pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596836ea0b63d8ab314e4554f01fa90e
https://doi.org/10.1038/onc.2014.120

Directed Molecular Evolution Reveals Gaussia Luciferase Variants with Enhanced Light Output Stability

Autor: M. Hannah Degeling, Casey A. Maguire, Marie Tannous, Bakhos A. Tannous, Mark C. de Gooijer, Grant K. Lewandrowski, M. Sarah S. Bovenberg, Carmen L.A.M. Vleggeert-Lankamp

Publikováno v: Degeling, M H, Bovenberg, M S S, Lewandrowski, G K, de Gooijer, M C, Vleggeert-Lankamp, C L A, Tannous, M, Maguire, C A & Tannous, B A 2013, ' Directed Molecular Evolution Reveals Gaussia Luciferase Variants with Enhanced Light Output Stability ', Analytical Chemistry, vol. 85, no. 5, pp. 3006-3012 . https://doi.org/10.1021/ac4003134
Analytical Chemistry, 85(5), 3006-3012. American Chemical Society
Analytical Chemistry, 85(5), 3006-3012

Gaussia Luciferase (Gluc) has proven to be a powerful mammalian cell reporter for monitoring numerous biological processes in immunology, virology, oncology and neuroscience. Current limitations of Gluc as a reporter include its emission of blue ligh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c508e331beb3b863a783ec6751d416
https://doi.org/10.1021/ac4003134

Single Reporter for Targeted Multimodal in Vivo Imaging

Autor: Edmund J. Keliher, Peter Waterman, John W. Chen, Johanna M. Niers, Gregory R. Wojtkiewicz, Elisabeth Garanger, Bakhos A. Tannous, Grant K. Lewandrowski, Ralph Weissleder, Mariam Kerami

Publikováno v: Niers, J M, Chen, J W, Lewandrowski, G, Kerami, M, Garanger, E, Wojtkiewicz, G, Waterman, P, Keliher, E, Weissleder, R & Tannous, B A 2012, ' Single Reporter for Targeted Multimodal in Vivo Imaging ', Journal of the American Chemical Society, vol. 134, no. 11, pp. 5149-5156 . https://doi.org/10.1021/ja209868g
Journal of the American Chemical Society, 134(11), 5149-5156. American Chemical Society

We have developed a multifaceted, highly specific reporter for multimodal in vivo imaging and applied it for detection of brain tumors. A metabolically biotinylated, membrane-bound form of Gaussia luciferase was synthesized, termed mbGluc-biotin. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7114408ff8fbab6ee3cfc0fb9aa13784
https://hdl.handle.net/1871/42823

Simultaneous in vivo monitoring of regulatory and effector T lymphocytes using secreted Gaussia luciferase, Firefly luciferase, and secreted alkaline phosphatase

Autor: Grant K, Lewandrowski, Ciara N, Magee, Marwan, Mounayar, Bakhos A, Tannous, Jamil, Azzi

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1098

Regulatory T cells (Tregs) are amongst the most widely studied cells in a variety of immune-mediated conditions, including transplantation and Graft Versus Host Disease (GVHD), cancer and autoimmunity; indeed, there is great interest in the tolerogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4d95808f3504fdd3983d2156eb84a631
https://pubmed.ncbi.nlm.nih.gov/24166380